StemgentSupplier Diversity Partner ALKALINE PHOSPHATE STAINING KI DFS Item

NC0088922 Specifications: 50 assays. Kit ComponentsFix Solution: 25 ml. AP Staining Solution A: 10 ml.AP Staining Solution B: 10 ml.AP Staining Solution C: 10 ml Specifications: 50 assays. Kit ComponentsFix Solution: 25 ml. AP Staining Solution A: 10 ml.AP Staining Solution B: 10 ml.AP Staining Solution C: 10 ml

StemgentSupplier Diversity Partner NUTRISTEM XF/FF CULTURE MEDIUM DFS Item

NC0345861 NutriStem XF/FF Culture Medium for Human iPS and ES Cells, 500ml. NutriStem XF/FF Culture Medium is a fully defined xeno-free, low growth factor human embryonic stem (ES) and induced pluripotent stem (iPS) cell feeder-free culture medium that enables maintenance and expansion of pluripotent stem cells. NutriStem Medium can be used to culture pluripotent stem cells for at least 20 passages while retaining pluripotency marker expression, robust proliferation with a normal karyotype, and the ability to differentiate into cells of all three germ layers in vitro and in vivo. NutriStem Medium offers the ability to culture cells in a completely xeno-free medium without the need for high levels of basic FGF and other stimulatory growth factors and cytokines. In addition, the superior cell attachment and proliferation observed with NutriStem Medium aid high-throughput screening applications. NutriStem XF/FF Culture Medium for Human iPS and ES Cells, 500ml. NutriStem XF/FF Culture Medium is a fully defined xeno-free, low growth factor human embryonic stem (ES) and induced pluripotent stem (iPS) cell feeder-free culture medium that enables maintenance and expansion of pluripotent stem cells. NutriStem Medium can be used to culture pluripotent stem cells for at least 20 passages while retaining pluripotency marker expression, robust proliferation with a normal karyotype, and the ability to differentiate into cells of all three germ layers in vitro and in vivo. NutriStem Medium offers the ability to culture cells in a completely xeno-free medium without the need for high levels of basic FGF and other stimulatory growth factors and cytokines. In addition, the superior cell attachment and proliferation observed with NutriStem Medium aid high-throughput screening applications.

StemgentSupplier Diversity Partner STEMOLECULE WNT INHB IWP-2 2MG DFS Item

NC9086357 Stemolecule™ Wnt Inhibitor IWP-2. Stemolecule Wnt Inhibitor IWP-2 was identified in a high throughput screen for antagonists of the Wnt/β-catenin pathway. Wnt Inhibitor IWP-2 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity. It also blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin1. Stemolecule™ Wnt Inhibitor IWP-2. Stemolecule Wnt Inhibitor IWP-2 was identified in a high throughput screen for antagonists of the Wnt/β-catenin pathway. Wnt Inhibitor IWP-2 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity. It also blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin1.

StemgentSupplier Diversity Partner Y27632 2MG IN SOLUTION DFS Item

NC0454602 Y27632 is a cell-permeable small molecule Rho-associated kinase (ROCK) inhibitor1. Y27632 has been found to prevent apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency2. This molecule has also been shown to enhance survival during the transplantation of ES cell-derived neural precursors3. Y27632 in combination with Pifithrin-a� significantly improves cell recovery after cryopreservation4. Y27632 is a cell-permeable small molecule Rho-associated kinase (ROCK) inhibitor1. Y27632 has been found to prevent apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency2. This molecule has also been shown to enhance survival during the transplantation of ES cell-derived neural precursors3. Y27632 in combination with Pifithrin-a� significantly improves cell recovery after cryopreservation4.

StemgentSupplier Diversity Partner SB431542 IN SOLUTION 5MG DFS Item

NC0548146 Stemolecule SB431542 in Solution, 5 mg (10 mM). SB431542 is an inhibitor of the transforming growth factor-beta 1 (TGF-b1) activin receptor-like kinases (ALKs). It is a selective and potent inhibitor of ALK-4, -5 and -7. SB431542 inhibits endogenous activin and TGF-b signaling without affecting more divergent BMP signaling utilizing ALK-1, -2, -3, and -61,2. SB431542 stimulates proliferation, differentiation, and sheet formation of endothelial cells derived from embryonic stem cells. Chemical name: 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide. 301836-41-9. Stemolecule SB431542 in Solution, 5 mg (10 mM). SB431542 is an inhibitor of the transforming growth factor-beta 1 (TGF-b1) activin receptor-like kinases (ALKs). It is a selective and potent inhibitor of ALK-4, -5 and -7. SB431542 inhibits endogenous activin and TGF-b signaling without affecting more divergent BMP signaling utilizing ALK-1, -2, -3, and -61,2. SB431542 stimulates proliferation, differentiation, and sheet formation of endothelial cells derived from embryonic stem cells. Chemical name: 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide. 301836-41-9.

StemgentSupplier Diversity Partner MESOFATE DIFFERENTIATION MEDIU DFS Item

NC0921696 MESOFATE DIFFERENTIATION MEDIU MESOFATE DIFFERENTIATION MEDIU

StemgentSupplier Diversity Partner STEMOLECULE WNT INHB IWP-4 2MG DFS Item

NC9086360 Stemolecule Wnt Inhibitor IWP-4, 2mg. Wnt Inhibitor IWP-4 was identified in a high throughput screen for antagonists of the Wnt / b-catenin pathway. Wnt Inhibitor IWP-4 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, there by blocking Wnt secretion and activity. It also blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and b-catenin1. Chemical name: 2-(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-ylthio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide 686772-17-8. Stemolecule Wnt Inhibitor IWP-4, 2mg. Wnt Inhibitor IWP-4 was identified in a high throughput screen for antagonists of the Wnt / b-catenin pathway. Wnt Inhibitor IWP-4 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, there by blocking Wnt secretion and activity. It also blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and b-catenin1. Chemical name: 2-(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-ylthio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide 686772-17-8.

StemgentSupplier Diversity Partner CRYOSTEM FREEZING MEDIUM 50ML DFS Item

NC0507468 CryoStem Freezing Medium (50ml) is a ready-to-use solution for the xeno-free cryopreservation of human embryonic stem (ES), induced pluripotent stem (iPS) and mesenchymal stem cells. Pluripotent stem cells preserved with CryoStem Freezing Medium result in high cell viability and recovery and express typical pluripotent markers after thawing. CryoStem Freezing Medium was developed to maintain xeno-free conditions during cryopreservation when culturing cells in a xeno-free environment. CryoStem Freezing Medium has been tested on human ES cells (H1, H9 and HuES9) and mesenchymal stem cells. Superior results were obtained in comparison with both serum-containing freezing media as well as competing serum-free products, making this an ideal product for cryopreservation of valuable human stem cell cultures. CryoStem Freezing Medium (50ml) is a ready-to-use solution for the xeno-free cryopreservation of human embryonic stem (ES), induced pluripotent stem (iPS) and mesenchymal stem cells. Pluripotent stem cells preserved with CryoStem Freezing Medium result in high cell viability and recovery and express typical pluripotent markers after thawing. CryoStem Freezing Medium was developed to maintain xeno-free conditions during cryopreservation when culturing cells in a xeno-free environment. CryoStem Freezing Medium has been tested on human ES cells (H1, H9 and HuES9) and mesenchymal stem cells. Superior results were obtained in comparison with both serum-containing freezing media as well as competing serum-free products, making this an ideal product for cryopreservation of valuable human stem cell cultures.

StemgentSupplier Diversity Partner Y27632 WEIGHT 2NG DFS Item

NC9818743 Y27632 is a cell-permeable small molecule Rho-associated kinase (ROCK) inhibitor. Size 2 mg. Y27632 has been found to prevent apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency. This molecule has also been shown to enhance survival during the transplantation of ES cell-derived neural precursors. Y27632 in combination with Pifithrin-? significantly improves cell recovery after cryopreservation. Y27632 is a cell-permeable small molecule Rho-associated kinase (ROCK) inhibitor. Size 2 mg. Y27632 has been found to prevent apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency. This molecule has also been shown to enhance survival during the transplantation of ES cell-derived neural precursors. Y27632 in combination with Pifithrin-? significantly improves cell recovery after cryopreservation.

StemgentSupplier Diversity Partner SSEA-1 ANTIBODY (PURIFIED) DFS Item

NC0958834 SSEA-1 Antibody (Purified), Mouse anti-Mouse/Human SSEA-1 Antibody (Purified), Mouse anti-Mouse/Human

StemgentSupplier Diversity Partner LDN-193189 IN SOLUTION DFS Item

NC0689818 Stemolecule LDN-193189 in Solution. LDN-193189 is a cell permeable small molecule inhibitor of bone morphogenetic protein (BMP) type I receptors ALK2 and ALK3 (IC50 = 5 nM and 30 nM respectively)1. LDN-193189 was derived from structure-activity relationship studies of Dorsomorphin and functions primarily through prevention of Smad1, Smad5, and Smad8 phosphorylation1-3. LDN-193189 only weakly inhibits ALK4, ALK5, and ALK71. BMP signaling coordinates developmental patterning and has essential physiological roles in mature organisms4,5. LDN-193189 has been used to reduce ectopic ossification in a mouse model of fibrodysplasia ossificans progressiva1. Stemolecule LDN-193189 in Solution. LDN-193189 is a cell permeable small molecule inhibitor of bone morphogenetic protein (BMP) type I receptors ALK2 and ALK3 (IC50 = 5 nM and 30 nM respectively)1. LDN-193189 was derived from structure-activity relationship studies of Dorsomorphin and functions primarily through prevention of Smad1, Smad5, and Smad8 phosphorylation1-3. LDN-193189 only weakly inhibits ALK4, ALK5, and ALK71. BMP signaling coordinates developmental patterning and has essential physiological roles in mature organisms4,5. LDN-193189 has been used to reduce ectopic ossification in a mouse model of fibrodysplasia ossificans progressiva1.

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