Bachem TRAP-6 Trifluoroacetate
TRAP-6 Trifluoroacetate, H-Ser-Phe-Leu-Leu-Arg-Asn-OH, 141136-83-6, C34H56N10O9, Mr 748.88, 5mg. PAR-1 (1-6) (human), Thrombin Receptor Activator Peptide 6, Proteinase Activated Receptor 1 (1-6) (human), Thrombin Receptor (1-6) (human), Coagulation Factor II Receptor (1-6) (human), SFLLRN. SFLLRN corresponds to residues 42-47 of the thrombin receptor. The hexapeptide acts as a thrombin receptor activator. It caused half-maximal platelet aggregation at approx. 0.8 uM and was 5 times more potent than the parent peptide H-8105. In addition, SFLLRN is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca2+.