[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P is a synthetic modified decapeptide derived from Substance P and supplied as a lyophilized powder for laboratory research. It is used to probe neuropeptide and chemokine receptor signaling, acting as a biased agonist that modulates G12 and JNK pathways and influences neutrophil migration and Ca2+ mobilization.
- Modified decapeptide sequence: {d-Arg}-Pro-Lys-Pro-{d-Phe}-Gln-{d-Trp}-Phe-{d-Trp}-Leu-Leu-NH2
- High purity (98.48%)
- Molecular weight 1516.83 Da
- Chemical formula C79H109N19O12
- Supplied as lyophilized powder for research use only
- Recommended storage: powder at -80°C for long-term stability