Lipids and Lipid Derivatives
eMolecules O-(2-Acetamido-2-deoxy-D-glucopyranosyl)-L-serine | | | 50mg
Toronto Research Chemicals | O-(2-Acetamido-2-deoxy-D-glucopyranosyl)-L-serine | 50mg | 483375068 | A157310 | | | | 308.287 | C11H20N2O8
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Cayman Chemical 4-NItrophenyl PalmItate 1g
A triterpene glycoside inhibits glucose-induced phosphorylation of serine 70 on S6K1 and serine 2448 on mTOR caspase-3 activity and apoptosis as well as increases authophagy in MIN-6 pancreatic B cells at 5 Ug/ml has been used as a reference compound to compare the potency of plant-derived sweet taste inhibitors
Cayman Chemical PalmItoleIc AcId-d13 25mg
An inhibitor of ABHD11 (IC50s 15 and 0 68 nM respectively in vitro and in situ) 100-fold selective for ABHD11 over approximately 20 serine hydrolases can be used as an anti-probe for ML-211
Cayman Chemical PalmItoleIc AcId-d13 10mg
ABlactamase inhibitor inhibits Ambler class A serine penicillinases and class C cephalosporinases including TEM-1 SHV-1 and P99 (IC50s 97 150 and 8 5 nM respectively) and the class D oxacillinase OXA-2 (IC50 10 nM) active against Gram-positive (MIC90s 2-128 Ug/ml) and Gram-negative bacteria (MIC90s 4-128 Ug/ml) when used in combination with piperacillin potentiates the activity of ceftolozane against Enterobacteriaceae in a neutropenic mouse model of thigh infection
Cayman Chemical PalmItelaIdIc AcId-d13 500ug
An inhibitor of MAGL (IC50s 14 and 27 nM for human and rat enzyme respectively) selective for MAGL over ABHD6 and PLA2G7 (IC50s 2 7 and 10 M respectively) as well as a panel of 33 serine hydrolases and a panel of 95 enzymes receptors transporters and ion channels at 10 M selective for MAGL over CYP1A2 CYP2C9 CYP2C19 and CYP3A4/5 (IC50s 50 M) inhibits MAGL activity in mouse and rat brain ex vivo (ED50s 1 4 and 0 5 mg/kg respectively) decreases brain levels of 2-AG in mice and rats reduces formalin-induced paw-licking time in rats