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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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2'-deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product is a precursor in the synthesis of Edoxudine and an analogue of 5-ethynyl-2'-deoxyuridine, EdU. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
Brain-penetrant pyrimidines nucleotide
Associated with nervous system diseases
Increases chromosome breakage
Decreases thymidylate synthetase activity
Reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury
Promising for Alzheimer's disease (AD) research
Appearance: Solid
Color: White to off-white
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2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of DNA. It serves as a substrate for UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, supporting DNA biosynthesis. This compound is intended for research use only and is not sold to patients.
Endogenous metabolite
Deoxynucleotide building block of DNA
Supports DNA biosynthesis
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A thymidine nucleoside derivative commonly used to identify proliferating cells; intraperitoneal injection of BrdU can be used in combination with neuronal markers to detect adult neurogenesis in animal models; commonly used as a marker of proliferation of cancer cells in vitro
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4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analog supplied as a light-yellow solid and used as a research reagent in studies of DNA synthesis, nucleoside metabolism, and antitumor mechanisms. It is characterized for biochemical and cell-based experiments and provided with supporting analytical data.
High purity (99.8%) for research applications.
Sulfur-substituted nucleoside for incorporation and metabolism studies.
Stable solid form with recommended low-temperature storage.
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4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analogue used in biochemical and nucleic acid research, including studies of nucleic acid chemistry and incorporation into oligonucleotides. It has molecular formula C9H12N2O4S, molecular weight 244.27 g/mol, and a reported purity of 99.78%.
Sulfur-substituted deoxyuridine analogue useful for nucleic acid studies.
High reported purity (99.8%), suitable for analytical and synthetic applications.
Available in multiple pack sizes for research-scale work.
Provided with certificate of analysis and safety data sheet for quality and handling.
Offered in solid form and as 10 mM DMSO solution for convenient use.
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2'-Deoxycytidine, a deoxyribonucleoside, can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
Deoxyribonucleoside
Inhibits biological effects of bromodeoxyuridine (Brdu)
Essential for the synthesis of nucleic acids
Can be used for cancer research
Inhibits tumor growth in mice
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