Nucleosides and Analogues
Medchemexpress LLC Adenosine receptor inhibitor 2 | 2550401-76-6 | 99.1% | 406.28 | 25 MG
Adenosine receptor inhibitor 2 (compound 14b) is a potent AR (adenosine receptor) inhibitor that exhibits dual affinity toward A1/A2A ARs, with a higher affinity for A1AR than A2AAR. It has Ki values of 52.2 nM for A1AR and 167 nM for A2AAR.
- Potent AR inhibitor.
- Dual affinity for A1/A2A adenosine receptors.
- Ki values of 52.2 nM for A1AR.
- Ki values of 167 nM for A2AAR.
- Targeted receptors include A1AR, A2AR, hA2B, and Adenosine A3 receptor.
- Purity of 99.08%.
- Molecular weight of 406.28.
- Appearance as a white to off-white solid.
![eMolecules 24292-60-2 | NADP disodium | Combi-Blocks | MFCD00077952 | 787.372 | C21H26N7Na2O17P3 | 98.000 | [Na+].[Na+].NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O | 25g | 517065493](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2459855.JPG-250.jpg)
eMolecules 24292-60-2 | NADP disodium | Combi-Blocks | MFCD00077952 | 787.372 | C21H26N7Na2O17P3 | 98.000 | [Na+].[Na+].NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O | 25g | 517065493
NADP disodium | Combi-Blocks | 24292-60-2 | MFCD00077952 | 787.372 | C21H26N7Na2O17P3 | 98.000 | [Na+].[Na+].NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O | 25g | 517065493
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MM * 1 ML
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
- Nucleoside analogue
- Can be incorporated into de novo-synthesized telomeres by telomerase
- Rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM (in vitro)
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies, superior to that observed with 6-thioguanine treatment (in vivo)
- Increases telomere dysfunction in tumor cells in vivo
- Appearance: Solid
- Color: White to yellow
Selleck Chemical LLC Ribavirin (ICN-1229) S2504-10mM/1mL
Ribavirin (NSC-163039 ICN-1229 RTCA Tribavirin) a synthetic guanosine analogue possesses a broad spectrum of activity against DNA and RNA viruses
Crescent Chemical Co Inc ATP NA2 SALT CRYS RESEARCH GRD
Adenosine-5'-triphosphate-Na2-salt cryst. research grade Size - 5G Storage Conditions - -15 °C TO -25 °C Catalog Number - 10920.02 CAS 987-65-5
Apexbio Technology LLC Adenosine Kinase Inhibitor (hydrate) 10mg
Adenosine Kinase Inhibitor (hydrate) is a small-molecule inhibitor targeting adenosine kinase It is designed to inhibit adenosine kinase thereby regulating intracellular adenosine metabolism Adenosine Kinase Inhibitor (hydrate) exerts its biological activity primarily through selective enzyme inhibition In cell-free conditions Adenosine Kinase Inhibitor (hydrate) demonstrates potent inhibitory activity with an IC50 value of approximately 1 7 nM Based on these pharmacological properties Adenosine Kinase Inhibitor (hydrate) holds research potential in investigating pain perception mechanisms and inflammation modulation through adenosine signaling pathways
Apexbio Technology LLC Motesanib Diphosphate (AMG-706) 857876-30-3 50mg
Motesanib Diphosphate (AMG-706 CAS 857876-30-3) is an oral small-molecule ATP-competitive inhibitor that targets vascular endothelial growth factor receptors (VEGFR1/2/3) platelet-derived growth factor receptor (PDGFR) c-Kit and Ret with reported IC50 values of 2 84 nM It demonstrates over 1000-fold selectivity for VEGFRs relative to EGFR Src and p38 kinases In vitro Motesanib Diphosphate potently inhibits VEGF-induced proliferation of human endothelial cells (IC50 10 nM) and blocks PDGF- and SCF-induced signaling while showing minimal effects on bFGF-stimulated proliferation In preclinical studies it suppresses angiogenesis and induces regression in tumor xenograft models Motesanib is under investigation in anti-angiogenic cancer research
Medchemexpress LLC Deoxycytidine triphosphate | 2056-98-6 | MFCD00135938 | 98.2% | 467.16 g/mol | C9H16N3O13P3 | 50 MG
Deoxycytidine triphosphate (dCTP) is a deoxynucleoside triphosphate used as a substrate for DNA polymerases in molecular biology. Supplied as a laboratory reagent, it is intended for enzymatic DNA synthesis applications such as PCR, cDNA synthesis, and DNA sequencing.
- High purity suitable for enzymatic DNA synthesis and PCR.
- Accurate molecular weight and formula for reagent planning.
- Supplied in a convenient small-scale package for method development.
- Stable when stored under recommended conditions to preserve activity.
- Commonly used as a deoxynucleotide substrate in sequencing and amplification workflows.
Medchemexpress LLC HY-F0002 100mg Medchemexpress, NADP (sodium salt) CAS:1184-16-3 Purity:>98%
Medchemexpress, HY-F0002 100mg NADP (sodium salt) CAS:1184-16-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 6-O-Methyl Guanosine | 7803-88-5 | 99.7% | 297.27 | 10 MG
6-O-Methyl Guanosine is a modified nucleoside that inhibits colony-forming ability in a malignant xeroderma pigmentosum cell line.
- Functions as a modified nucleoside
- Exhibits inhibition of colony-forming ability
- Relevant for nucleoside antimetabolite/analog research
Medchemexpress LLC Adenosine 5'-diphosphoribose sodium | 68414-18-6 | MFCD00136017 | 99.5% | 581.30 g·mol⁻1 | C15H22N5NaO14P2 | 1 ML
Adenosine 5′-diphosphoribose sodium is supplied as a ready-to-use aqueous solution (10 mM, 1 mL) for biochemical research. It functions as an ADP-ribose reagent and metabolite standard for studies of NAD+ metabolism and ADP-ribosylation, and is characterized by high reported purity and defined storage recommendations.
- Ready-to-use 10 mM solution in water, 1 mL.
- Approximately 99.5% purity.
- Molecular weight 581.30 g·mol⁻1.
- CAS number 68414-18-6 for unambiguous identification.
- Suitable as a biochemical reagent and metabolite standard in NAD+ and ADP-ribosylation research.
- Storage recommended at -80°C in solution for long-term stability.
Medchemexpress LLC 2′-deoxycytidine-5′-triphosphate dilithium salt | 2687960-70-7 | 95.7% | 493.11 g/mol | C9D14Li2N3O13P3 | 5 MG
Deuterium-labeled deoxycytidine triphosphate in dilithium form supplied for use as an isotopic internal standard and tracer in analytical and biochemical workflows. It is intended for applications requiring an isotopically labeled nucleotide reference such as mass spectrometry, quantitative assays, and tracer studies.
- Deuterium-labeled nucleotide for isotopic tracing.
- Provided as a dilithium salt, compatible with common solvents.
- High purity suitable for analytical use (e.g., ~95.7%).
- Molecular weight 493.11 g/mol; formula C9D14Li2N3O13P3.
- Useful as an internal standard for mass spectrometry and quantitative assays.
- Store according to supplier recommendations to maintain stability.