Nucleosides and Analogues
Medchemexpress LLC HY-33212 100mg Medchemexpress, D-N-Acetylgalactosamine CAS:1811-31-0 Purity:>98%
Medchemexpress, HY-33212 100mg D-N-Acetylgalactosamine CAS:1811-31-0 D-N-Acetylgalactosamine is an endogenous metabolite. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC 1-[3-(difluoromethyl)-1,2-thiazol-5-yl]-3-[2-fluoro-5-(hydroxymethyl)pyridin-4-yl]urea | 2270879-17-7 | 99.0% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000233904.png-250.jpg)
Medchemexpress LLC 1-[3-(difluoromethyl)-1,2-thiazol-5-yl]-3-[2-fluoro-5-(hydroxymethyl)pyridin-4-yl]urea | 2270879-17-7 | 99.0% | 25 MG
Small-molecule inhibitor of BRM (SMARCA2) and BRG1 (SMARCA4) ATPase activity supplied as a milligram-scale research reagent for in vitro studies.
- Targets BRM (SMARCA2) and BRG1 (SMARCA4) ATPase activity.
- CAS registry number 2270879-17-7.
- Chemical formula C11H9F3N4O2S.
- Molecular weight 318.28 g/mol.
- Reported purity up to 99% (supplier dependent).
- Provided as a 25 mg powder, intended for research use only.
Medchemexpress LLC a-D-Glucosamine pent 10g | 7784-54-5 | 10 G
Alpha-D-glucosamine pentaacetate is the fully acetylated derivative of D-glucosamine used as an intermediate and reagent in glycobiology and carbohydrate chemistry. It is supplied as a solid for synthetic and analytical workflows, including derivatization and glycan synthesis.
- Fully acetylated amino sugar derivative for carbohydrate synthesis.
- High purity suitable for research (≥97.0%).
- Useful as a synthetic intermediate and for glycobiology studies.
- Solid form for convenient storage and handling.
- Molecular formula C16H23NO10; molecular weight 389.35 g·mol⁻¹; CAS 7784-54-5.
Medchemexpress LLC Malvidin-3-O-arabinoside chloride | 28500-04-1 | 97.10% | 498.86 | 1 MG
Malvidin-3-O-arabinoside chloride ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. It upregulates LAMP-1 expression, restores lysosomal acidity, strengthens lysosomal functions, and stimulates phosphorylation of AMP-activated protein kinase (AMPK).
- Upregulates LAMP-1 expression
- Restores lysosomal acidity
- Strengthens lysosomal functions
- Stimulates phosphorylation of AMP-activated protein kinase (AMPK)
- Inhibits excess ROS generation
- Enhances GSH level
- Enhances autophagy flux
- Up-regulates the LC3-II/LC3-I ratio
Medchemexpress LLC Guanosine (Standard) | 118-00-3 | 99.5% | 283.24 | 250 MG
Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. It exhibits anti-HSV activity. As an analytical standard, it is intended for research and analytical applications. In vitro, Guanosine can be phosphorylated into guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP), which are crucial for various biochemical processes including nucleic acid and protein synthesis, photosynthesis, muscle contraction, and intracellular signal transduction.
- Used as a reference standard for assays.
- Commonly utilized in qualitative, quantitative, and methodological research experiments.
- Supports applications such as HPLC, GC, and MS.
Medchemexpress LLC Uridine 3',5'-diphosphate | 2922-95-4 | C9H14N2O12P2 | 25 MG
Uridine 3′,5′-diphosphate (3′,5′-UDP) is identified as a competitive RNase inhibitor. This compound is suitable for various laboratory research applications.
- Competitive RNase inhibitor
- High purity (99.65%)
- Solid, white to off-white appearance
- Powder stable for 3 years at -20°C
- In solvent stable for 6 months at -80°C and 1 month at -20°C
- Soluble in water at 125 mg/mL (requires sonication)
Medchemexpress LLC Alpha-Guanosine | 15398-66-0 | C10H13N5O5 | 25 MG
Alpha-Guanosine is a purine nucleoside analog that exhibits broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
- Purine nucleoside analog
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC 2'-Deoxyguanosine (standard) | 961-07-9 | MFCD00080300 | 99.2% | 267.24 | 50 MG
2'-Deoxyguanosine (Standard) is the analytical standard for 2'-Deoxyguanosine. It is intended for research and analytical applications. This purine nucleoside exhibits diverse biological activities, including inducing DNA division in mouse thymus cells and acting as a potent cell division inhibitor in plant cells. In vitro, it inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively.
- Analytical standard for 2'-deoxyguanosine
- Intended for research and analytical applications
- Induces DNA division in mouse thymus cells
- Potent cell division inhibitor in plant cells
- Inhibits clonal growth of HL-60 and K562 leukemia cells
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 99.21% | 267.24 | 100 MG
2'-Deoxyguanosine (Standard) is an analytical standard of 2'-Deoxyguanosine, intended for research and analytical applications. It is a purine nucleoside with various biological activities, including inducing DNA division in mouse thymus cells and acting as a potent cell division inhibitor in plant cells. It also inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively.
- Analytical standard for 2'-Deoxyguanosine.
- Intended for research and analytical applications.
- Purine nucleoside with various biological activities.
- Induces DNA division in mouse thymus cells.
- Potent cell division inhibitor in plant cells.
- Inhibits clonal growth of HL-60 and K562 leukemia cells (IC50 values of 50 and 80 μM).
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Medchemexpress LLC Adenosine 5'-triphosphate(ATP)-d4 (ammonium salt) | 2483831-82-7 | C10H24D4N9O13P3 | 5.79 MG
Adenosine 5'-triphosphate(ATP)-d4 (ammonium salt) is a deuterium labeled ATP ammonium salt. It serves as a tracer and an internal standard for quantitative analysis, leveraging deuterium substitution's potential to influence pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration affects pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-Uridine | 26287-69-4 | 244.20 | 250 MG
L-Uridine is an enantiomer of the normal RNA constituent D-uridine. It can be isolated from the Polyporaceae fungus *Poria cocos* (Schw.) and acts as a phosphate acceptor for nucleoside phosphotransferases. In vitro, L-uridine (7 min) is converted to 5'-L-uridylic acid, with a Km value of 28 mM.
- Enantiomer of D-uridine
- Isolated from *Poria cocos* (Schw.)
- Acts as a phosphate acceptor for nucleoside phosphotransferases
- High purity (99.81%)
- Available as a solid
- Soluble in various in vitro dissolution methods
- Stable under specified storage conditions
Medchemexpress LLC Guanosine, 6-O-methyl- | 7803-88-5 | 99.7% | 297.27 | 25 MG
6-O-Methyl Guanosine is identified as a modified nucleoside. Research indicates its capacity to inhibit the colony-forming ability in a malignant xeroderma pigmentosum cell line, suggesting potential applications in cell biology studies related to cell proliferation and specific genetic disorders. This modified nucleoside provides a tool for investigating cellular mechanisms and could contribute to understanding pathways involved in malignancy.
- Modified nucleoside.
- Inhibits colony-forming ability in a malignant xeroderma pigmentosum cell line.
Apexbio Technology LLC 2-Deoxyadenosine 958-09-8 100mg
2-Deoxyadenosine (CAS 958-09-8) is a synthetic purine nucleoside analog that functions as a demethylated nucleoside in biological systems Structurally similar to adenosine but lacking a hydroxyl group at the 2 position it selectively pairs with deoxythymidine during DNA synthesis 2-Deoxyadenosine influences regulatory pathways associated with DNA replication and repair serving as a molecular probe to study these processes It is extensively utilized in molecular biology and genomics for investigating DNA synthesis repair mechanisms and the dynamics of nucleic acid metabolism