Nucleosides and Analogues
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate (trisodium), PCR grade | 54680-12-5 | PCR Grade | 557.13 | 1 ML
2'-Deoxyadenosine-5'-triphosphate trisodium, 100 mM solution, PCR Grade, is a nucleotide utilized by cells for DNA synthesis and replication. It serves as a raw material for DNA polymerase to synthesize long DNA strands and is also used in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification. This product is supplied as an aqueous solution.
- Substrate for DNA polymerase
- Facilitates DNA synthesis and replication
- Suitable for reverse transcription polymerase chain reaction (RT-PCR)
- Aqueous solution format
eMolecules Combi-Blocks Uridine 1kg 267162937 OR-1852 98 000 58-96-8 MFCD00006526 244 203 C9H12N2O6
Combi-Blocks Uridine 1kg 267162937 OR-1852 98 000 58-96-8 MFCD00006526 244 203 C9H12N2O6
Apexbio Technology LLC UDP disodium salt(Synonyms: Uridine 5'-diphosphate disodium salt, Uridine diphosphate disodium salt, UDP-Na2), 10mM (in 1mL H2O), CAS: 27821-45-0.
UDP disodium salt (CAS 27821-45-0) is a selective agonist targeting the P2Y6 receptor exhibiting potent stimulatory activity with an EC50 value of approximately 300 nM and a reported pEC50 of 6 52 for the human P2Y6 receptor Endogenously UDP serves as a metabolite involved in catalyzing glucuronidation reactions facilitating the conjugation of glucuronic acid to diverse substrates Due to these biological properties UDP disodium salt finds utility in researching disease-related mechanisms and RNA biosynthesis pathways
Sigma Aldrich Fine Chemicals Biosciences BETA-Nicotinamide mononucleotide, 1094-61-7, MFCD00038748, 25 mg
Empirical Formula (Hill Notation): C11H15N2O8P, Molecular Weight: 334.22, ≥95% (HPLC), storage temp: −20°C, Synonym: β-NMN, β-Nicotinamide ribose monophosphate, NMN, Nicotinamide ribotide, Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate.
Biotium Primary Antibody CA15 3 CD227 EMA MUC1 VU-4H5 CF740 1/EA
MAb VU-4H5 reacts with MUC1 a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia The dominant epitope of MAb VU4H5 is APDTR as established with epitope fingerprinting VU-4H5 preferentially binds to under-glycosylated tumor MUC1 The extracellular domain of MUC1 largely consists of a highly conserved O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver
Medchemexpress LLC Adenosine receptor antagonist 2 | 2703054-47-9 | 99.4% | C23H21FN8O | 10MG
Adenosine receptor antagonist 2 is a small-molecule, orally active antagonist of A2a and A2b adenosine receptors with potent activity (IC50 1 nM at A2a, 3 nM at A2b) and reported anti-tumor effects. It is intended for research use in pharmacology and target-validation studies and is accompanied by supporting analytical documentation.
- Potent A2a and A2b receptor antagonism (IC50 1 nM and 3 nM).
- Orally active in preclinical models.
- Reported anti-tumor activity in studies.
- Supplied with analytical documentation, including datasheet, COA, and SDS.
- Suitable for in vitro and in vivo pharmacology and target validation.
Sigma Aldrich Fine Chemicals Biosciences beta Nicotinamide adenine100MG
beta Nicotinamide adenine100MG
Sigma Aldrich Fine Chemicals Biosciences 5 Bromo 2 deoxyuridine 5 t5MG
5-Bromo-2AE-deoxyuridine 5AE-triphosphate is used for incorporation into DNA for studying normal and tumor cell proliferation profiles.
Medchemexpress LLC Lamivudine | 134678-17-4 | 100 MG
Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). It can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the central nervous system (CNS). It appears as a solid and has a molecular weight of 229.26. Its identified uses include laboratory chemicals and the manufacture of substances.
- Orally active nucleoside reverse transcriptase inhibitor
- Inhibits HIV reverse transcriptase 1/2
- Inhibits reverse transcriptase of hepatitis B virus
- Salicylate form can penetrate the CNS
- Solid appearance
- Molecular weight of 229.26
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5-triphosphate disodium salt hydrate BioXtra, 99 (HPLC), from microbial, 34369-07-8, MFCD00150755
Adenosine 5-triphosphate disodium salt hydrate BioXtra, 99 (HPLC), from microbial
Medchemexpress LLC Adenosine receptor inhibitor 2 | 2550401-76-6 | 99.1% | 406.28 g/mol | C17H20BrN5O2 | 10 MG
Adenosine receptor inhibitor 2 is a small-molecule research compound that acts as an adenosine receptor inhibitor with reported dual affinity for A1 and A2A receptors. It is supplied as a high-purity analytical standard intended for pharmacology and receptor-binding studies.
- High-purity small-molecule suitable for receptor pharmacology.
- Dual affinity for A1 and A2A adenosine receptors.
- Chemical formula C17H20BrN5O2, molecular weight 406.28 g/mol.
- CAS number 2550401-76-6 for substance identification.
- Available in milligram-scale packages, including 10 mg.
- Structural identifiers available (SMILES) for cheminformatics use.
- For research use only; not for human consumption or clinical use.
Medchemexpress LLC Uridine | 58-96-8 | 100.0% | 5 G
Uridine is a nucleoside compound composed of uracil and a ribose ring, connected by a β-N1-glycosidic bond. This compound is used for research purposes and has demonstrated various biological activities.
- Inhibits the proliferation of HL-60 leukemia cells
- Alleviates CCl4-induced liver fibrosis in mice
- Shows anti-ischemic, antioxidant, and anti-arrhythmic effects in rat models
Medchemexpress LLC 2'-Deoxyuridine (Standard) | 951-78-0 | 99.2% | 25 MG
2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine, intended for research and analytical applications. It is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Used as an analytical standard.
- Precursor in the synthesis of Edoxudine.
- Analogue of 5-ethynyl-2'-deoxyuridine.
- Reduces microglial activation.
- Improves oxidative stress damage.
- Promising for Alzheimer's disease research.
- Utilized in HPLC, GC, and MS research experiments.