c-di-AMP diammonium is a STING agonist that activates the TBK3-IRF3 signaling pathway, leading to the production of type I IFN and TNF. It also acts as a bacterial second messenger, regulating cell growth, survival, and virulence in Gram-positive bacteria, and modulating the host immune response. This compound functions as a potent mucosal adjuvant, stimulating both humoral and cellular responses.
- STING agonist
- Bacterial second messenger regulating cell growth, survival, and virulence in Gram-positive bacteria
- Regulates host immune response
- Potent mucosal adjuvant stimulating humoral and cellular responses