Environmental Testing Standards
Apexbio Technology LLC Uniconazole 83657-22-1 10g
Uniconazole (CAS 83657-22-1) is a small-molecule inhibitor of cytochrome P450 707A enzymes (CYP707As) which are involved in the catabolism of abscisic acid (ABA) via 8 -hydroxylation In in vitro assays uniconazole demonstrated potent inhibition of CYP707A3 activity with a reported Ki of 68 nM surpassing other plant growth retardants such as paclobutrazol and tetcyclacis In Arabidopsis models uniconazole treatment elevated endogenous ABA levels and enhanced drought tolerance effects that were independent of gibberellin-mediated pathways Uniconazole is therefore utilized in plant biology research to study ABA metabolism and stress responses
Apexbio Technology LLC Amoxicillin 26787-78-0 10g
Amoxicillin (26787-78-0) is a small-molecule inhibitor targeting bacterial penicillin-binding proteins (PBPs) It is designed to disrupt bacterial cell wall biosynthesis thereby impairing peptidoglycan cross-linking and compromising cell wall integrity Amoxicillin exerts its biological activity primarily through inhibition of PBPs interfering with the processes critical to bacterial cell wall formation In in vitro studies Amoxicillin demonstrates inhibitory activity with IC50 values ranging from 0 1 to 5 g/mL depending on experimental conditions and organism susceptibility Based on these pharmacological properties Amoxicillin holds research potential in studies of bacterial infection mechanisms antimicrobial responses and resistance development
TARGETMOL CHEMICALS INC DESCHLOROCLOZAPINE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Deschloroclozapine a metabolite of Clozapine is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM respectively. purity: 99%
Apexbio Technology LLC PTP Inhibitor I 2491-38-5 10g
PTP Inhibitor I (CAS 2491-38-5) is a small molecule inhibitor targeting protein tyrosine phosphatases (PTPs) specifically SHP-1 and PTP1B with inhibition constants (KI) of 43 M and 42 M respectively As an -bromoacetophenone derivative it acts as a neutral phosphotyrosine mimetic covalently modifying the active site cysteine of PTPs Structure-activity studies indicate that modifications to the phenyl ring moderately affect potency while para-substituted peptidyl groups can enhance both potency and selectivity PTP Inhibitor I is utilized in vitro for mechanistic studies of PTP function related to diabetes neurodegenerative disorders immune regulation and pathogen virulence Animal and clinical data are not available
Apexbio Technology LLC Diclofenac Potassium 15307-81-0 10g
Diclofenac potassium (CAS 15307-81-0) is a synthetic small molecule belonging to the nonsteroidal anti-inflammatory drug (NSAID) class It functions primarily by inhibiting cyclooxygenase (COX) enzymes thereby reducing the synthesis of prostaglandins involved in inflammation and nociception Through this mechanism diclofenac potassium attenuates inflammatory responses and mediates analgesic effects It is frequently utilized in biomedical research to study inflammatory pathways investigate mechanisms of pain modulation and evaluate anti-inflammatory interventions in cellular and preclinical models
Apexbio Technology LLC (-)-Tetramisole 16595-80-5 10g
(-)-Tetramisole is an immunomodulatory agent that stimulates nicotinic acetylcholine receptors leading to the activation of T-lymphocytes macrophages and phagocytic cells to enhance cell-mediated immune responses (-)-Tetramisole exerts its biological activity primarily through activation of nicotinic acetylcholine receptors Additionally it is utilized in the investigation of epigenetic regulation pathways involving lysine-specific demethylase 1 (LSD1) serving as a research tool to study chromatin modulation mechanisms and gene expression control Based on these pharmacological properties (-)-Tetramisole holds research potential in immunological signaling studies and tumor biology
Aqua Solutions Ammonia Nitrogen Standard 1 ppm | 12125-02-9 | MFCD00143604 | 4 L
Ammonia Nitrogen Standard 1 ppm | Mol Wt: 53.49 | 12125-02-9 | MFCD00143604 | 4 L