Organometallic Compounds
Medchemexpress LLC Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside | 4099-85-8 | 96.0% | 204.22 | 25 G
Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside is a furanose derivative. It serves as an important intermediate for the synthesis of compounds such as arsenic-containing ribosides.
- Furanose derivative.
- Important intermediate for the synthesis of arsenic-containing ribosides.
- For research use only.
Medchemexpress LLC Ak-778-xxmu | 1227045-76-2 | MFCD16882561; MFCD08272115 | 100.0% | 392.83 g/mol | C22H17ClN2O3 | 5 MG
A potent small-molecule research reagent that antagonizes DNA binding protein 2 (ID2), with demonstrated binding (KD ≈129 nM) and cellular activity inhibiting glioma cell migration and inducing apoptosis.
- Small-molecule antagonist of DNA binding protein 2 (ID2) with KD ≈129 nM.
- Inhibits glioma cell migration and invasion, and induces apoptosis in cell models.
- High purity (99.96%) and off-white to light yellow solid appearance.
- Molecular formula C22H17ClN2O3; molecular weight 392.83 g/mol.
- Recommended solvent: DMSO, 100 mg/mL (use ultrasonic and freshly opened DMSO).
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solution store at -80°C.
eMolecules TRIMETHYLSILYLMETHYL AZIDE | 87576-94-1 | MFCD00059964 | 1g
AstaTech | TRIMETHYLSILYLMETHYL AZIDE | 1g | 494131739 | T73022 | 97.000 | 87576-94-1 | MFCD00059964 | 129.238 | C4H11N3Si
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Cambridge Isotope Laboratories Methyl methacrylate (D8 98%) 10-100 ppm hydroquinone 1 g
Methyl methacrylate (D8 98%) 10-100 ppm hydroquinone 1 g
Cambridge Isotope Laboratories 12C Methane QG Diamond 2400L /-5% (12C 99 99% N2 1ppm) CP 99 5% 2400 L
12C Methane QG Diamond 2400L /-5% (12C 99 99% N2 1ppm) CP 99 5% 2400 L
Medchemexpress LLC Methyl 2,3-O-isopropylidene-β-D-ribofuranoside | 4099-85-8 | 96.0% | 204.22 | 5 G
Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside is a furanose derivative that serves as an important intermediate for the synthesis of compounds such as arsenic-containing ribosides. This high-purity chemical is suitable for various research applications.
- Furanose derivative
- Intermediate for synthesizing arsenic-containing ribosides
- 96.0% purity
- Soluble in DMSO (100 mg/mL)
- Multiple in vivo dissolution protocols provided
- Extensive documentation available
- Cited in scientific publications
- For research use only
Medchemexpress LLC PI3K/Akt/CREB activator 1 (compound AE-18) | 2708177-73-3 | C19H15F4NO3 | 50 MG
PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active activator that promotes neuronal proliferation, induces differentiation of Neuro-2a cells, and accelerates axon-dendrite polarization of primary hippocampal neurons. It achieves this by upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway and is used in vascular dementia (VaD) research.
- Promotes neuronal proliferation and differentiation
- Accelerates axon-dendrite polarization of primary hippocampal neurons
- Upregulates brain-derived neurotrophic factor (BDNF)
- Improves cerebral blood flow recovery in models of chronic cerebral hypoperfusion (CCH)
- Mitigates impairment of learning and memory in CCH models
- Alleviates CCH-induced pathological injury in the hippocampus
Apexbio Technology LLC PS-1145 431898-65-6 5mg
PS-1145 (CAS 431898-65-6) is a selective inhibitor of I B kinase (IKK) with an IC50 of 88 nM IKK is a critical component of the upstream NF- B signaling pathway regulating cellular responses to inflammation In vitro studies have demonstrated that PS-1145 blocks TNF -induced NF- B activation in multiple myeloma (MM) cells in a dose- and time-dependent manner increases I B protein levels suppresses IL-6-mediated anti-apoptotic effects and inhibits expression of ICAM-1 Additionally PS-1145 reduces IL-6 secretion from bone marrow stromal cells (BMSCs) and partially limits MM cell proliferation In vivo PS-1145 has been shown to induce apoptosis in DMBA-induced skin tumors in rats by inhibiting NF- B and VEGF activity The compound remains in the preclinical research stage
Medchemexpress LLC Tolterodine tartrate | 124937-52-6 | 98.6% | C26H37NO7 | 1 ML
Tolterodine tartrate is a mAChR inhibitor and a substrate for cytochrome P450 enzymes. It competitively binds acetylcholine, which reduces sympathetic excitation and inhibits involuntary bladder muscle contraction. It restores the Nrf2/NF-κB signaling pathway, providing protection against inflammatory response and ferroptosis, and ameliorates LPS-induced reactive oxygen species production and lipid oxidation. This product can be used for research related to urinary tract infections and overactive bladder.
- Competitively binds acetylcholine
- Reduces sympathetic excitation
- Inhibits involuntary bladder muscle contraction
- Restores Nrf2/NF-κB signaling pathway
- Provides protection against inflammatory response and ferroptosis
- Ameliorates LPS-induced reactive oxygen species production and lipid oxidation