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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Used in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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m-PEG5-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules consisting of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These molecules function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and not sold to patients.
Purity: 99.02%
Molecular weight: 251.32
Formula: C11H25NO5
CAS number: 5498-83-9
Appearance: Liquid (density: 1.023±0.06 g/cm³)
Color: Colorless to light yellow
SMILES: COCCOCCOCCOCCOCCN
Leverages the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Sitafloxacin hydrate is an orally active fluoroquinolone antibiotic with in vitro activity against a broad spectrum of Gram-positive and -negative bacteria, including anaerobic bacteria and atypical pathogens. It is utilized in the study of respiratory and urinary tract infections, and exhibits good activity against Mycobacterium avium in vivo.
Orally active fluoroquinolone antibiotic
Active against a broad spectrum of Gram-positive and -negative bacteria
Effective against anaerobic bacteria and atypical pathogens
Used in respiratory tract infection studies
Used in urinary tract infection studies
Shows good activity against Mycobacterium avium in mice
Eliminates bacteria in the spleen and lungs
Demonstrates strong activity against mycobacteria in macrophages
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DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Non-cleavable 3 unit PEG ADC linker
Contains a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups
For research use only
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Bis-NH2-C1-PEG3, also known as PROTAC Linker 24, is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Appearance: colorless to light yellow liquid
Molecular formula: C10H24N2O3
Molecular weight: 220.31
Storage: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light)
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