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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are molecules that contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Facilitates selective degradation of target proteins
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Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1] Azide-PEG3-Desthiobiotin is a click chemistry reagent it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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m-PEG3-OMs is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Used in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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Mal-PEG5-acid is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. These molecules contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. PROTACs function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is intended for research use only.
PEG-based PROTAC linker for chemical synthesis
Utilizes the ubiquitin-proteasome system for selective protein degradation
Molecular weight: 389.40
Chemical formula: C17H27NO9
Purity: ≥97.0%
Appearance: Light brown to yellow liquid
Soluble in DMSO (100 mg/mL)
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Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound also functions as a click chemistry reagent, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Furthermore, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when combined with molecules containing DBCO or BCN groups.
Functions as a PEG-based PROTAC linker
Used in the synthesis of PROTACs
Acts as a click chemistry reagent
Capable of copper-catalyzed azide-alkyne cycloaddition with alkyne-containing molecules
Undergoes strain-promoted alkyne-azide cycloaddition with DBCO or BCN groups
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Mal-PEG3-NH2 TFA is a linear heterobifunctional polyethylene glycol crosslinker supplied as the trifluoroacetic acid (TFA) salt. It features a maleimide group for selective thiol conjugation and a primary amine for subsequent modification, making it useful as a non-degradable PROTAC linker and general bioconjugation reagent for research applications.
Maleimide and primary amine functional groups for orthogonal conjugation.
Supplied as TFA salt for enhanced stability and handling.
High purity suitable for research-scale bioconjugation (≈99.1%).
Available in small mg packaging for precision experiments.
Non-degradable (non-cleavable) linker for stable conjugates.
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Br-PEG3-MS is a PEG-based PROTAC linker employed in the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research use only.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Exploits the ubiquitin-proteasome system
Selectively degrades target proteins
For research use only
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More