Tolterodine tartrate is an mAChR inhibitor and a substrate for cytochrome P450 enzymes. It competitively binds acetylcholine, which reduces sympathetic excitation and inhibits involuntary bladder muscle contraction. It has also shown to restore the Nrf2/NF-κB signaling pathway, providing protection against inflammatory responses and ferroptosis. This compound can ameliorate LPS-induced reactive oxygen species production and lipid oxidation, making it suitable for research on urinary tract infections and overactive bladder.
- mAChR inhibitor and cytochrome P450 substrate
- Reduces sympathetic excitation
- Inhibits involuntary bladder muscle contraction
- Restores Nrf2/NF-κB signaling pathway
- Protects against inflammatory responses and ferroptosis
- Ameliorates LPS-induced oxidative stress
- Used for urinary tract infection and overactive bladder research