Glycosyl compounds
Medchemexpress LLC Plantainoside D | 147331-98-4 | 5 MG
Plantainoside D is a phenylethanoid glycoside and an IKK-β inhibitor with diverse biological activities. It shows inhibitory activity of angiotensin-converting enzyme (ACE) and reduces glutamate release from nerve terminals. It also alleviates cell apoptosis and improves acute lung injury (ALI) induced by sepsis, making it suitable for studies in neuroprotection, antioxidant, anti-inflammation, and antihypertension.
- Phenylethanoid glycoside and an IKK-β inhibitor
- Inhibits angiotensin-converting enzyme (ACE) with an IC50 of 2.17 mM
- Reduces glutamate release from nerve terminals by inhibiting voltage-dependent calcium channels and protein kinase C signaling
- Alleviates cell apoptosis by inhibiting ROS generation and NF-κB activation
- Improves acute lung injury (ALI) induced by sepsis by regulating the Sirt3/NLRP3 signaling pathway
Medchemexpress LLC Gala tfa | 99.3% | 3032.36 (free base) | 1 MG
GALA (TFA) is a biologically active peptide and a pH-sensitive fusogenic peptide. It is a promising method to accelerate the process of enhancing the expression of desired proteins.
- Purity: 99.34%
- Molecular weight: 3032.36 (free base)
- Appearance: Solid
- Color: White to off-white
- Sequence: Trp-Glu-Ala-Ala-Leu-Ala-Glu-Ala-Leu-Ala-Glu-Ala-Leu-Ala-Glu-His-Leu-Ala-Glu-Ala-Leu-Ala-Glu-Ala-Leu-Glu-Ala-Leu-Ala-Ala
- Solubility (in vitro): DMSO: 12.5 mg/mL (ultrasonic and warming and heat to 60°C)
![eMolecules 709-50-2 | Methyl ??-D-glucopyranoside | Ambeed | MFCD00006602 | 194.183 | C7H14O6 | 98.000 | CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O | 100g | 633658512](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000491069.jpg-250.jpg)
eMolecules 709-50-2 | Methyl ??-D-glucopyranoside | Ambeed | MFCD00006602 | 194.183 | C7H14O6 | 98.000 | CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O | 100g | 633658512
Methyl ??-D-glucopyranoside | Ambeed | 709-50-2 | MFCD00006602 | 194.183 | C7H14O6 | 98.000 | CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O | 100g | 633658512
Apexbio Technology LLC Anti-Amyloid-Beta-Ab-Donanemab
Anti-Amyloid Beta Antibody (Donanemab) (CAS No 1931944-80-7) is a monoclonal antibody under investigation in the field of neurodegenerative research specifically for Alzheimer s disease Originating from biotechnology developments its primary mechanism involves targeting amyloid beta plaques which are believed to contribute to Alzheimer s pathology It binds to a specific epitope on deposited amyloid plaques promoting clearance and reducing their accumulation Common in vitro activity has been observed in the nanomolar to low micromolar range Typical applications include use in cell models animal studies and drug screening assays to assess efficacy and mechanistic pathways Experimental concentrations typically depend on the specific research design
Medchemexpress LLC Rhein 8-O-β-D-Glucopyranoside | 34298-86-7 | 1 MG
Rhein 8-O-β-D-Glucopyranoside is an anthraquinone glycoside found in rhubarb, known for its purgative activity. This compound has a molecular weight of 446.36, a chemical formula of C21H18O11, and appears as a light yellow to yellow solid. It is derived from plants, specifically Polygonaceae Rheum palmatum L.
- Anthraquinone glycoside
- Found in rhubarb
- Exhibits purgative activity
- Molecular weight: 446.36
- Chemical formula: C21H18O11
- Appears as a solid
- Color: light yellow to yellow
- Initial source: plants, Polygonaceae Rheum palmatum L.
- Purity: 99.81%
Medchemexpress LLC 7-Aminoactinomycin D | 7240-37-1 | ≥99.0% | 1270.43 | 1 MG
7-Aminoactinomycin D (7-AAD) is a cell-impermeant fluorescent DNA stain and a potent RNA polymerase inhibitor. It selectively binds to GC regions of DNA and also exhibits antibacterial effects. It is used as a DNA dye to distinguish viable, apoptotic, and late apoptotic/dead cells in flow cytometry.
- Cell-impermeant fluorescent DNA stain.
- Potent RNA polymerase inhibitor.
- Selectively binds to GC regions of DNA.
- Exhibits antibacterial effects.
- Distinguishes viable, apoptotic, and late apoptotic/dead cells in flow cytometry.
- Can be used at different concentrations for specific staining purposes in flow cytometry.
Medchemexpress LLC Aurachin D | 108354-13-8 | 5 MG
Aurachin D is an antibiotic that inhibits gram-positive bacteria and certain fungi. It also blocks NADH oxidation in beef heart submitochondrial particles. This laboratory chemical, with molecular formula C25H33NO and molecular weight 363.54, appears as a solid and is intended for research use only.
- Inhibits gram-positive bacteria
- Inhibits certain fungi
- Blocks NADH oxidation in beef heart submitochondrial particles
- Acts as an antibiotic targeting bacterial and fungal infections
- Exhibits cytotoxicity against mouse L929 cells
Medchemexpress LLC Eriodictyol-7-O-glucoside | 38965-51-4 | 25 MG
Eriodictyol-7-O-glucoside is a flavonoid and Nrf2 activator, demonstrating significant scavenging effects on hydroxyl radicals and superoxide anions. It increases Nrf2 nuclear localization and induces Nrf2/ARE-dependent gene expression, providing protection against oxygen and glucose deprivation (OGD)-induced oxidative insult. It also shows neuroprotective efficacy in a rat model of focal cerebral ischemia.
- Nrf2 activator
- Scavenges hydroxyl radicals and superoxide anions
- Increases nuclear localization of Nrf2
- Induces Nrf2/ARE-dependent gene expression
- Protects against oxidative insult
- Demonstrates neuroprotective efficacy in focal cerebral ischemia models
- Can be used for the study of stroke