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Carbohydrate derivatives in which a sugar is bound to another functional group via a glycosidic bond; play numerous roles in living organisms; may be classified and utilized based on glycone/presence of sugar, bond type, or agylcone.
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D-AP5 (D-APV; D-2-amino-5-phosphonovaleric acid) is a selective, competitive NMDA receptor antagonist (Kd ≈ 1.4 μM) that inhibits the glutamate binding site of NMDA receptors. It is used as a pharmacological tool in neuroscience to block NMDA receptor-mediated responses. The compound is supplied as a solid with manufacturer guidance for preparing defined stock solutions and specified storage conditions.
Selective, competitive NMDA receptor antagonist.
Blocks the glutamate binding site of NMDA receptors.
Useful for studying NMDA-dependent synaptic transmission and plasticity.
Supplied as a powder with guidance to prepare defined stock solutions.
Storage guidance: powder -20°C; solutions -80°C (long-term) or -20°C (short-term).
Defined chemical identifiers: CAS 79055-68-8; molecular weight 197.13 g/mol.
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D-AP5 is a selective, competitive antagonist of NMDA-type ionotropic glutamate receptors. It binds the glutamate recognition site to inhibit NMDA receptor-mediated synaptic transmission and is widely used in neuroscience research for studying excitatory signaling and synaptic plasticity.
Selective, competitive NMDA receptor antagonist.
Suitable for in vitro and in vivo studies of NMDA-mediated signaling.
Solubility: water soluble (~2 mg/mL with ultrasonic); poor solubility in DMSO and ethanol.
Storage: powder stable at -20°C for up to 3 years; store solutions at -80°C for long term.
Includes molecular and identifier data to ensure accurate compound selection.
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D-AP5 (CAS 79055-68-8) is a selective antagonist of the NMDA receptor It competitively inhibits glutamate binding at the NMDA receptor site exhibiting an affinity constant (Kd) of approximately 1 4 M In animal research administration of D-AP5 leads to impairment in spatial learning tasks specifically causing deficits in sensorimotor function and spatial memory performance Due to its targeted action on NMDA receptors D-AP5 serves as an important pharmacological tool for studying glutamate-related synaptic plasticity learning and memory mechanisms
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