Monosaccharides
Medchemexpress LLC NSC-87877 (disodium) | 56932-43-5 | 503.42 | 25 MG
NSC-87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1). This compound also inhibits dual-specificity phosphatase 26 (DUSP26).
- Potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases
- Exhibits IC50 values of 0.318 μM for Shp2
- Exhibits IC50 values of 0.355 μM for Shp1
- Inhibits dual-specificity phosphatase 26 (DUSP26)
Medchemexpress LLC NSC-87877 (disodium) | 56932-43-5 | 98.0% | 503.42 | 50 MG
NSC-87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases, with IC50 values of 0.318 μM and 0.355 μM for Shp2 and Shp1, respectively. It also inhibits dual-specificity phosphatase 26 (DUSP26).
- Potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases
- Inhibits dual-specificity phosphatase 26 (DUSP26)
- Inhibits DUSP26 function in NB cell lines
- Results in increased p53 phosphorylation and activation
- Possesses excellent anti-neuroblastoma activity in vivo
Apexbio Technology LLC Phosphatase Inhibitor Cocktail (1 Tube, EDTA-Free, 100X)(Synonyms: Phosphatase Inhibitor Cocktail, Phosphatase Inhibitor Mix, Phosphatase Inhibitor Set), 10X1ml.
Phosphatase Inhibitor Cocktail (1 Tube EDTA-Free 100X) provides comprehensive inhibition of various phosphatases including acid and alkaline phosphatases serine/threonine phosphatases (e g PP1 PP2A PP2B) and protein tyrosine phosphatases (PTPs) By suppressing phosphatase enzymatic activities it preserves phosphorylation states of proteins in lysates from mammalian plant yeast insect or bacterial samples ensuring more accurate downstream analysis It is applicable in protein lysate preparations immunoprecipitations nuclear extracts and processing of fixed tissues (e g FFPE) to maintain phosphorylation modifications
Apexbio Technology LLC Phosphatase Inhibitor Cocktail (1 Tube, EDTA-Free, 100X)(Synonyms: Phosphatase Inhibitor Cocktail, Phosphatase Inhibitor Mix, Phosphatase Inhibitor Set), 100X1ml.
Phosphatase Inhibitor Cocktail (1 Tube EDTA-Free 100X) provides comprehensive inhibition of various phosphatases including acid and alkaline phosphatases serine/threonine phosphatases (e g PP1 PP2A PP2B) and protein tyrosine phosphatases (PTPs) By suppressing phosphatase enzymatic activities it preserves phosphorylation states of proteins in lysates from mammalian plant yeast insect or bacterial samples ensuring more accurate downstream analysis It is applicable in protein lysate preparations immunoprecipitations nuclear extracts and processing of fixed tissues (e g FFPE) to maintain phosphorylation modifications
Apexbio Technology LLC Phosphatase Inhibitor Cocktail (1 Tube, EDTA-Free, 100X)(Synonyms: Phosphatase Inhibitor Cocktail, Phosphatase Inhibitor Mix, Phosphatase Inhibitor Set), 50X1ml.
Phosphatase Inhibitor Cocktail (1 Tube EDTA-Free 100X) provides comprehensive inhibition of various phosphatases including acid and alkaline phosphatases serine/threonine phosphatases (e g PP1 PP2A PP2B) and protein tyrosine phosphatases (PTPs) By suppressing phosphatase enzymatic activities it preserves phosphorylation states of proteins in lysates from mammalian plant yeast insect or bacterial samples ensuring more accurate downstream analysis It is applicable in protein lysate preparations immunoprecipitations nuclear extracts and processing of fixed tissues (e g FFPE) to maintain phosphorylation modifications
Apexbio Technology LLC Phosphatase Inhibitor Cocktail (1 Tube, EDTA-Free, 100X)(Synonyms: Phosphatase Inhibitor Cocktail, Phosphatase Inhibitor Mix, Phosphatase Inhibitor Set), 1ml.
Phosphatase Inhibitor Cocktail (1 Tube EDTA-Free 100X) provides comprehensive inhibition of various phosphatases including acid and alkaline phosphatases serine/threonine phosphatases (e g PP1 PP2A PP2B) and protein tyrosine phosphatases (PTPs) By suppressing phosphatase enzymatic activities it preserves phosphorylation states of proteins in lysates from mammalian plant yeast insect or bacterial samples ensuring more accurate downstream analysis It is applicable in protein lysate preparations immunoprecipitations nuclear extracts and processing of fixed tissues (e g FFPE) to maintain phosphorylation modifications
Medchemexpress LLC NSC-87877 (disodium) | 56932-43-5 | 98.0% | 503.42 | C19H11N3Na2O7S2 | 10 MG
NSC-87877 disodium is the disodium salt form of a small-molecule inhibitor of protein tyrosine phosphatases SHP-1 and SHP-2, intended for research use in biochemical and cell-based studies. It is provided as a solid and characterized for biochemical potency and composition.
- Potent inhibitor of SHP-1 and SHP-2 (IC50 ≈ 0.318 μM and 0.355 μM).
- Provided as the disodium salt for improved solubility and handling.
- High purity (98.0%) suitable for research applications.
- Molecular weight 503.42 and formula C19H11N3Na2O7S2 for precise mass calculations.
- Available in small milligram pack sizes for screening and assay development.