Sugar acids and derivatives
Chem-Impex International, Inc. N-Acetylneuraminic acid | 131-48-6 | MFCD00006620 | 1G
N-Acetylneuraminic acid, 131-48-6, MFCD00006620, 1G
Medchemexpress LLC Beta-D-glucuronide-pNP-carbonate | 894095-98-8 | MFCD31715405 | >96.0% | 913.83 g/mol | C45H43N3O18 | 50 MG
β-D-glucuronide-pNP-carbonate is a glycosidase-cleavable antibody-drug conjugate (ADC) linker that contains a para-nitrophenyl carbonate reactive handle and a β-D-glucuronide cleavable trigger. It is supplied as a solid for research use and is designed to release payloads upon enzymatic cleavage by glucuronidase.
- Glycosidase-cleavable linker for targeted payload release.
- Para-nitrophenyl carbonate reactive handle for payload attachment.
- Solid form suitable for standard laboratory handling.
- Available in small research-scale quantities for synthesis work.
- Intended for research use only; not for clinical or human use.
Medchemexpress LLC Aloeresin D | 105317-67-7 | MFCD32004290 | 99.5% | 556.56 | C29H32O11 | 10 MG
Aloeresin D is a chromone glycoside isolated from Aloe vera that inhibits β-secretase (BACE1) with a reported IC50 of 39 μM. It is supplied as a purified research compound with defined solubility and storage recommendations for biochemical and pharmacological studies.
- Chromone glycoside isolated from Aloe vera.
- Inhibits β-secretase (BACE1); IC50 = 39 μM.
- High purity (≈99.5%).
- Molecular formula C29H32O11; molecular weight 556.56 g/mol.
- Soluble in DMSO (250 mg/mL); reported in vivo solubility ≥2.08 mg/mL.
- Solid storage: 4°C, sealed, protected from moisture and light.
Medchemexpress LLC IL-1RA/IL-1F3 Porci 500ug | 500ug
IL-1RA/IL-1F3 proteins are powerful anti-inflammatory antagonists in the interleukin 1 family specifically targeting the pro-inflammatory cytokines IL1B and IL1A This protein counteracts the inflammatory effects of IL1 playing a critical role in preventing immune dysregulation and preventing uncontrolled systemic inflammation triggered by a variety of innate irritants including pathogens IL-1RA/IL-1F3 Protein Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein expressed by E coli with tag free
Apexbio Technology LLC D-AP5(Synonyms: D-2-Amino-5-phosphonopentanoic acid, D-APV, D(-)-2-Amino-5-phosphonovaleric acid), 10mg, CAS: 79055-68-8.
D-AP5 (CAS 79055-68-8) is a selective antagonist of the NMDA receptor It competitively inhibits glutamate binding at the NMDA receptor site exhibiting an affinity constant (Kd) of approximately 1 4 M In animal research administration of D-AP5 leads to impairment in spatial learning tasks specifically causing deficits in sensorimotor function and spatial memory performance Due to its targeted action on NMDA receptors D-AP5 serves as an important pharmacological tool for studying glutamate-related synaptic plasticity learning and memory mechanisms
Medchemexpress LLC β-D-glucopyranosiduronic acid p-nitrophenyl carbonate derivative | 894095-98-8 | 99.6% | 913.83 g/mol | C45H43N3O18 | 1 G
β-D-glucuronide-pNP-carbonate is a glucuronide-cleavable carbonate linker used to attach payloads to antibodies for research-scale antibody-drug conjugate (ADC) synthesis. It is supplied as a purified small-molecule reagent for linker-payload assembly and analytical characterization.
- Cleavable glucuronide-based linker responsive to glycosidase cleavage.
- Reported purity around 99.6%.
- Molecular formula C45H43N3O18; molecular weight 913.83 g/mol.
- Available in small-scale packaging including 1 G; larger quantities available on request.
- Supporting documents include datasheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC Integrin alpha V beta 5 protein | >95.0% | 20UG
Integrin alpha V beta 5 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant human integrin αVβ5 dimer expressed in HEK293 cells and supplied biotinylated with C-Avi and C-His tags. It is provided in microgram quantities and intended for receptor-ligand interaction studies, biochemical assays, and biophysical analyses that require the native extracellular domains.
- Biotinylated C-Avi and C-terminal His tags for detection and capture
- Expressed in HEK293 cells to preserve mammalian post-translational modifications
- High purity >95% as determined by reducing SDS-PAGE
- Molecular weight range 85-140 kDa consistent with heterodimeric extracellular domains
- Available in multiple microgram sizes to suit different assay scales
Medchemexpress LLC Collagenase (type D, animal-free) | 9001-12-1 | 10 MG
Collagenase (Type D, animal-free) is an enzymatic preparation for tissue digestion and dissociation in research applications. It combines collagenase and secondary protease activities and exhibits higher activity than comparable Type A preparations.
- Animal-free enzyme preparation suitable for tissue dissociation.
- Contains collagenase and secondary protease activities; higher activity than type A.
- Available in multiple sizes, including a 10 mg quantity.
- CAS no. 9001-12-1.
- Appearance: off-white to light yellow solid.
- Solubility: ≥ 50 mg/mL in water (in vitro).
- Storage: follow the certificate of analysis for recommended conditions.
- For research use only; not for patient use.
Cayman Chemical Febuxostat Acyl GlucuronID 1mg
A metabolite of febuxostat; is formed via glucuronidation of febuxostat by UGTs