Sugar acids and derivatives
Medchemexpress LLC Integrin alpha 5 bet 5ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Flag C-10 His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) has molecular weight of 101 35 kDa
Medchemexpress LLC D-α-hydroxyglutaric acid disodium | 103404-90-6 | MFCD00069573 | >95.0% | 192.08 | C5H6Na2O5 | 25 MG
D-α-hydroxyglutaric acid disodium is the disodium salt of the R-enantiomer of 2-hydroxyglutarate, provided as a research reagent for biochemical and analytical studies. It is the principal metabolite in D-2-hydroxyglutaric aciduria and acts as a weak competitive antagonist of α-ketoglutarate, affecting α-KG-dependent dioxygenases. Molecular formula C5H6Na2O5; molecular weight 192.08; store at 4°C, sealed and away from moisture.
- Disodium salt form for improved solubility and handling.
- R-enantiomer specificity for enantioselective biological studies.
- Inhibits α-KG-dependent dioxygenases for mechanistic assays.
- Useful for biochemical, metabolic, and analytical research applications.
- Known molecular formula and molecular weight for formulation and dosing calculations.
- Stable when stored sealed at 4°C away from moisture.
Chem-Impex International, Inc. 4-Methylumbelliferyl-b-D-glucuronide hydrate | 6160-80-1 | MFCD09039280 | 1G
4-Methylumbelliferyl-b-D-glucuronide hydrate, 6160-80-1, MFCD09039280, 1G
Chem-Impex International, Inc. 4-Methylumbelliferyl-b-D-glucuronide hydrate | 6160-80-1 | MFCD09039280 | 5G
4-Methylumbelliferyl-b-D-glucuronide hydrate, 6160-80-1, MFCD09039280, 5G
Medchemexpress LLC Integrin alpha V bet 100ug
Integrin V beta 3 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 3 Protein Human (HEK293 C-His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein expressed by HEK293 with C-10 His labeled tag Integrin alpha V beta 3 Protein Human (HEK293 C-His) has molecular weight of 90 31 110-150 kDa respectively
Medchemexpress LLC CMP-sialic acid sodium salt | 1007117-62-5 | MFCD00151579 | 90.8% | 636.43 g/mol | C20H30N4NaO16P | 5 MG
CMP-Sialic acid sodium salt is a nucleotide sugar involved in the biosynthesis of sialic acid. It functions as an allosteric inhibitor of UDP-GlcNAc 2-epimerase and provides a substrate for Golgi sialyltransferases, making it useful for enzymatic sialylation and studies of glycan modification in biochemical research.
- Provides substrate activity for Golgi sialyltransferases.
- Acts as an allosteric inhibitor of UDP-GlcNAc 2-epimerase.
- Supports enzymatic sialylation and glycan modification studies.
- Supplied as a solid, white to off-white, with defined storage stability.
- Available in small research-scale quantities for laboratory use.
Medchemexpress LLC 2-(4-heptylphenethyl)-6-hydroxybenzoic acid | 1243583-85-8 | MFCD22123243 | 99.6% | 340.46 g/mol | C22H28O3 | 10 MG
MG 149 is a small-molecule inhibitor of Tip60 (histone acetyltransferase) used in preclinical research to probe acetyltransferase activity and related mitochondrial pathways. It shows activity versus MOF/KAT8 and can influence PINK1-dependent mitochondrial clearance; supplied as a white to off-white solid with high analytical purity for laboratory use.
- Tip60 (HAT) inhibitor with reported IC50 ≈ 74 μM for Tip60 and ≈ 47 μM for MOF.
- High purity (HPLC 99.6%).
- Chemical formula C22H28O3; molecular weight 340.46 g/mol.
- White to off-white solid suitable for bench-scale research.
- Storage: powder at -20°C (stable 3 years) or 4°C (stable 2 years); in solvent at -80°C (2 years) or -20°C (1 year).
- Common applications: epigenetics assays, acetyltransferase inhibition studies, and mitochondrial/PINK1 pathway research.
Medchemexpress LLC NH2-C6-ARC186 sodium | 92.5% | 12,881.00 | 10 MG
NH2-C6-ARC186 sodium is an NH2-C6-modified aptamer supplied as the sodium salt that inhibits complement C5 convertase activity. The terminal aminohexyl (NH2-C6) linker enables covalent coupling to other peptides or molecules for conjugation studies. It is provided as a white to off-white solid with defined purity and molecular weight for research applications in small milligram quantities.
- Function: complement C5 convertase inhibitor
- NH2-C6 aminohexyl linker for conjugation
- Purity: 92.5%
- Physical form: white to off-white solid
- Typical sizes: 1 mg, 5 mg, 10 mg, larger sizes by quote
- Storage: in solvent -80°C (6 months) or -20°C (1 month); sealed and dry
- Molecular weight approximately 12,881 Da
![Medchemexpress LLC 2-((6-(4-chlorophenyl)-1-methyl-4H-triazolo[4,3-a]azepin-4-yl)methyl)-5-methyl-1,3,4-oxadiazole | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237008.png-250.jpg)
Medchemexpress LLC 2-((6-(4-chlorophenyl)-1-methyl-4H-triazolo[4,3-a]azepin-4-yl)methyl)-5-methyl-1,3,4-oxadiazole | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MG
BET-BAY 002 is a research-grade small-molecule BET bromodomain inhibitor used in epigenetic and oncology research. It is supplied as a white to off-white solid (CAS 1588521-78-1) with a molecular weight of 403.86 g/mol and reported high purity for reliable experimental use. The compound dissolves readily in DMSO and has recommended storage conditions for long-term stability.
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
