Sugar acids and derivatives
Apexbio Technology LLC Amyloid Beta-Peptide (1-40) (human) 131438-79-4 25mg
Amyloid Beta-Peptide (1-40) (human) (CAS 131438-79-4) is a synthetic peptide composed of 40 amino acids identical to residues 1-40 of human amyloid-beta (A ) characterized by molecular weight of 4329 8 Da Derived from amyloid precursor protein (APP) via sequential proteolytic cleavage by - and -secretases A peptides form extracellular plaques and vascular deposits commonly observed in Alzheimer s disease pathology A 40 is among the predominant isoforms generated primarily through cleavage in the transmembrane region of APP within the Golgi apparatus As a model peptide A (1-40) is widely employed to study amyloid fibril formation neurotoxicity mechanisms and therapeutic strategies targeting Alzheimer s disease progression
Medchemexpress LLC D-α-Hydroxyglutaric acid | 13095-47-1 | 98.0% | 148.11 | 25 MG
D-α-Hydroxyglutaric acid | 13095-47-1 | 98.0% | 148.11 | 25 MG
Medchemexpress LLC [D-Ala2]-GIP (human) | 444073-04-5 | 98.97% | 4983.60 | 25 MG
[D-Ala2]-GIP (human) is a GIP receptor agonist with an EC50 of 630 pM. It improves glucose tolerance and demonstrates neuroprotective activity in an MPTP-induced Parkinson's disease model. Additionally, it enhances cognitive function and hippocampal synaptic plasticity in obese diabetic rats. This product is suitable for research related to type 2 diabetes, Parkinson's disease, and similar conditions.
- Acts as a GIP receptor agonist with an EC50 of 630 pM
- Improves glucose tolerance by stimulating insulin release
- Demonstrates neuroprotective activity in MPTP-induced Parkinson's disease models
- Enhances cognitive function and hippocampal synaptic plasticity in obese diabetic rats
- Attenuates the behavioral phenotype of Parkinson's disease
- Reverses decline in motor ability and reduces muscle stiffness
- Inhibits the increase of MDA levels in the brain
Apexbio Technology LLC PKH26 Red Fluorescent Cell Linker Kit(Synonyms: PKH26 Cell Membrane Dye, PKH26 Fluorescent Cell Labeling Kit), 25T.
PKH26 Red Fluorescent Cell Linker Kit comprises the red fluorescent probe PKH26 designed specifically to label cellular membranes PKH26 integrates stably into lipid regions of cell membranes emitting red fluorescence and enabling clear visualization of cells Due to low cytotoxicity low nonspecific background fluorescence and minimal dye transfer to neighboring unlabeled cells PKH26 has broad utility in tracking cells both in vitro and in vivo Its fluorescence is evenly partitioned between daughter cells during proliferation diminishing with each round of cell division facilitating proliferation assays PKH26 is frequently employed alone or in combination with PKH67 for cell tracking studies and proliferation analyses
Medchemexpress LLC Integrin alpha 8 bet 5ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-10 His C-Flag labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) has molecular weight of 85-140 kDa
Medchemexpress LLC Cathepsin D and E FRET Substrate acetate | 99.8% | 1816.15 | 25 MG
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate specifically for cathepsins D and E, and not for cathepsins B, H, or L. The cleavage of this substrate occurs at the Phe-Phe amide bond. It serves as a valuable tool for routine assays and mechanistic studies concerning cathepsins E and D.
- Fluorogenic substrate
- Specific for cathepsins D and E
- Does not act on cathepsins B, H, or L
- Cleavage at the Phe-Phe amide bond
- Suitable for routine assays
- Useful for mechanistic studies on cathepsins E and D