Sugar acids and derivatives
Alkali Scientific 4 Methylumbelliferyl β D cellobiopyranoside, 100 Mg
Methylumbelliferyl Cellobiopyranoside is a high-purity reagent used in biochemical analysis to assess the activity of cellulase enzymes, particularly those involved in the breakdown of cellulose and related polysaccharides. This 100mg reagent is essential for enzyme assays designed to measure the hydrolysis of cellobiose or other cellulose derivatives. It is widely utilized in studies of plant biomass degradation, biofuel production, and the enzymatic processing of agricultural and industrial waste. The high purity of this reagent ensures consistent and reliable results in laboratory experiments focusing on cellulase activity and cellulolytic enzymes.
Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 25 MG
BET bromodomain inhibitor 1 is an orally active and selective inhibitor of bromodomain and extra-terminal (BET) bromodomains. It demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest, inhibiting c-Myc expression, and upregulating p21 levels. Its primary applications involve research into acute myeloid leukemia, acute leukemia, and multiple myeloma.
- Orally active and selective BET bromodomain inhibitor.
- High affinity for BRD4 (IC50: 2.6 nM) and other BET bromodomains.
- Demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest.
- Effective against various cancer cell lines (Kasumi 1, MM1.S, MV4-11, and RS4-11).
- Excellent selectivity for BET bromodomain family over other bromodomains.
- Does not inhibit five cytochrome P450 enzymes.
- Exhibits strong antitumor activities in in-vivo models.
Medchemexpress LLC SN-38 glucuronide | 121080-63-5 | 99.5% | 568.53 | 1 MG
SN-38 glucuronide, also known as SN-38G, is an inactive metabolite of the anticancer molecule Irinotecan. It has known toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor used in research for colon and rectal cancer. SN-38 glucuronide can be reactivated by gut microbial β-glucuronidase enzymes, which remove the glucuronic acid moiety, thus increasing its toxic effects on the intestine.
- Inactive metabolite of Irinotecan.
- Has toxic effects on the gastrointestinal tract.
- Can be reactivated by gut microbial β-glucuronidase enzymes.
- Relevant in the study of colon and rectal cancer.
- Cells metabolizing SN38 to SN38-G show increased resistance to extracellular SN38.
AdipoGen 3OH-C10-L-HSL
Chemical. CAS 192883-12-8. Formula C14H25NO4. MW 271.35. Synthetic. N-3-hydroxydecanoyl-L-homoserine lactone is a small diffusible signaling molecule secreted by various bacteria and involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching. The applications of this molecule include regulation of virulence and exoproteases.
Medchemexpress LLC N-Acetylneuraminic acid | 131-48-6 | 99.9% | 309.27 | 1 G
N-Acetylneuraminic acid (NANA; Lactaminic acid) is a nonphenolic sialic acid found predominately in Collocalia esculenta. It is involved in various biological processes, including myocardial injury, melanoma, and viral or bacterial infections. This compound inhibits melanogenesis by reducing tyrosinase activity and triggers myocardial injury in vitro and in vivo through activation of the Rho/Rho-associated signaling pathway. It may also prevent high fat diet-induced inflammation and oxidative stress, thereby mitigating hyperlipidemia-associated conditions.
- Inhibits melanogenesis by reducing tyrosinase activity.
- Triggers myocardial injury in vitro and in vivo.
- May prevent high fat diet-induced inflammation and oxidative stress.
- Promising for research in melanoma, coronary artery disease, obesity-related diseases, and hyperlipidemia.
Medchemexpress LLC Hydroxypyruvic acid | 1113-60-6 | 104.06 | 1 MG
Hydroxypyruvic acid is an intermediate in the metabolism of glycine, serine, and threonine. It serves as a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. This compound is involved in the metabolic disorder of dimethylglycine dehydrogenase deficiency pathway.
- Targeted as an endogenous metabolite
- Used in metabolic disease research
- Applicable in human gut microbiota metabolites research
- Classified under ketones, aldehydes, and acids
- Useful in disease research fields
- Source classification research applications
![eMolecules Cis-3-BOC-6-Aminomethyl-3-azabicyclo[3.1.0]hexane | Combi-Blocks, Inc.MFCD16294637 | 212.293 | C11H20N2O2 | 95.000 | CC(C)(C)OC(=O)N1C[C@H]2C(CN)[C@H]2C1 | 1g | 603144335](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502192674.JPG-250.jpg)
eMolecules Cis-3-BOC-6-Aminomethyl-3-azabicyclo[3.1.0]hexane | Combi-Blocks, Inc.MFCD16294637 | 212.293 | C11H20N2O2 | 95.000 | CC(C)(C)OC(=O)N1C[C@H]2C(CN)[C@H]2C1 | 1g | 603144335
Cis-3-BOC-6-Aminomethyl-3-azabicyclo[3.1.0]hexane | Combi-Blocks, Inc.MFCD16294637 | 212.293 | C11H20N2O2 | 95.000 | CC(C)(C)OC(=O)N1C[C@H]2C(CN)[C@H]2C1 | 1g | 603144335
Medchemexpress LLC N-Acetylneuraminic acid | 131-48-6 | MFCD00006620 | 99.95 % | 309.27 | 5 G
N-Acetylneuraminic acid (NANA), also known as Lactaminic acid, is a nonphenolic sialic acid found predominantly in Collocalia esculenta. It plays a crucial biological role in various physiological and pathological processes. NANA has been shown to inhibit melanogenesis and may help prevent high-fat diet (HFD)-induced inflammation and oxidative stress, making it a promising subject for research in various conditions.
- Inhibits melanogenesis by reducing tyrosinase activity.
- Triggers myocardial injury in vitro and in vivo.
- May prevent high-fat diet (HFD)-induced inflammation and oxidative stress.
- Mitigates hyperlipidemia-associated inflammation and oxidative stress.
- Promising for research in melanoma, coronary artery diseases, obesity-related conditions, and hyperlipidemia.