Sugar acids and derivatives
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
Sigma Aldrich Fine Chemicals Biosciences HiPrepTM Heparin Fast Flow
HiPrep(TM) Heparin FF 16/10 is prepacked with Heparin Sepharose(R) 6 Fast FLow for preparative purification of proteins with affinity for heparin such as DNA-binding proteins coagulation factors lipoproteins and protein synthesis factors.
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
Sigma Aldrich Fine Chemicals Biosciences Sialic Acid Quantitation K
The Sialic Acid Quantitation Kit provides a rapid and accurate determination of total N-acetylneuraminic acid (NANA sialic acid). NANA is released from glycoconjugates using neuraminidase. The kit uses alpha(2-3 6 8 9) neuraminidase to cleave all NANA linkages including alpha(2-8) and alpha(2-9) linkages as well as branched NANA for the most accurate determination of total sialic acid content.
Sigma Organic Chemistry GUAIACYLGLYCEROL-BETA-G | 10mg | 7382-59-4 | MFCD00060144
GUAIACYLGLYCEROL-BETA-G , 10mg
About this item:
CAS #: 7382-59-4
MDL #: MFCD00060144
Molecular Weight: 320.34
UNSPSC Code: 12352200
Sigma Organic Chemistry H-Met-beta-naphthylamid 2 | 25mg | MFCD00190955
H-Met-beta-naphthylamid 2, 25mg
About this Item:
MDL #: MFCD00190955
Molecular Weight: 274.38
UNSPSC Code: 12352200
Chemical Formula: C15H18N2OS
Sigma Organic Chemistry D-(+)-Neopterin | 10MG | 2009-64-5 | MFCD00042801
D-(+)-Neopterin, 10MG
About This Item:
Storage: 2-8C
EINECS Number: 217-924-7
Ambeed 2R 3R 4S 5S 6S 2Bromo6 methox
(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate, 21085-72-3, 97%
TARGETMOL CHEMICALS INC N-Glycolylneuraminic acid 10MG
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. N-Glycolylneuraminic acid (GcNeu) is a nonhuman sialic acid molecule synthesized in pigs. N-Glycolylneuraminic acid is a receptor of human and animal IAVs. Purity ≥98%
Cayman Chemical QuercetIn 3-O-glucuronIde 25mg
An aminopeptidase B inhibitor that is commonly used to characterize novel proteases
Sigma Aldrich Fine Chemicals Biosciences Heparin sodium salt from p
SODIUM Heparin sodium salt from p
Cayman Chemical D-GlucuronIc AcId 10g
An isothiocyanate with anticancer activity inhibits GPX activity reduces cellular GSH levels and induces ROS accumulation in T72 ovarian epithelial cells expressing H-RasV12 at 10 UM induces cell cycle arrest at the G2/M phase and apoptosis in PL45 MIA PaCa-2 and BxPC-3 pancreatic cancer cells at 10 UM decreases the number of tumor cells expressing Ki-67 or PCNA and reduces tumor growth in a MIA PaCa-2 mouse xenograft model