Sugar acids and derivatives
Medchemexpress LLC IFN-beta Rhesus Mac 10ug
IFN-beta Protein Rhesus Macaque (HEK293 Fc Solution) is the recombinant rhesus macaque-derived IFN-beta protein expressed by HEK293 with C-mFc tag
Medchemexpress LLC Integrin alpha 8 bet 5ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-His labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 His) has molecular weight of 120-140 kDa 100-120 kDa respectively
Medchemexpress LLC Integrin alpha X bet 5ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His labeled tag Integrin alpha X beta 2 Protein Human (HEK293 His) has molecular weight of 130-150 kDa (ITGAX) 85-96 kDa (ITGB2) respectively
Medchemexpress LLC Integrin alpha 6 bet 100ug
Integrin alpha 6 beta 1 Protein Human (HEK293 Flag-His) is the recombinant human-derived Integrin alpha 6 beta 1 protein expressed by HEK293 with C-His C-Flag labeled tag has molecular weight of 110 130 kDa respectively
Medchemexpress LLC Integrin alpha 8 bet 500ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-10 His C-Flag labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) has molecular weight of 85-140 kDa
Medchemexpress LLC Integrin alpha X bet 100ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 Flag His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His C-Flag labeled tag
Medchemexpress LLC Protac α-synuclein degrader 3 | 2412273-77-7 | ≥98.0% | C51H68N6O11S2 | 10MG
PROTAC α-synuclein degrader 3 is a proteolysis-targeting chimera developed for research applications to induce ubiquitination and proteasomal degradation of α-synuclein, useful in Parkinson's disease model studies. It has documented in vitro and in vivo formulation solubility and recommended storage conditions for stable handling.
- Selective α-synuclein degrader that promotes ubiquitination and proteasomal degradation.
- Demonstrated to reduce α-synuclein levels (≈65% reduction at 1 μM).
- Soluble in DMSO at 100 mg/mL with ultrasonic assistance.
- Formulatable for in vivo dosing in multiple vehicle systems at ≥2.5 mg/mL.
- Stable when stored as powder at 4°C; in solution store at -80°C (6 months) or -20°C (1 month).
- For research use only; not intended for clinical or therapeutic use.
Medchemexpress LLC Mal-va-mac-SN38 | 2778229-31-3 | 97.9% | 1040.14 g/mol | C52H61N7O14S | 10 MG
Mal-va-mac-SN38 is a drug-linker conjugate for antibody-drug conjugate (ADC) research that delivers the SN-38 cytotoxin via a maleimide-based va-mac linker. It is supplied as a characterized research reagent for in vitro and in vivo ADC studies.
- High purity (97.9%).
- Contains SN-38 cytotoxin payload for ADC applications.
- Maleimide-based va-mac linker for conjugation compatibility.
- Supplied in a small research quantity (10 MG).
- Characterized with datasheet, certificate of analysis, and safety data sheet available.
- Intended for ADC development and cancer research applications.
![Medchemexpress LLC 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl-thiazolo[4,5-d]pyrimidine-2-thione | 2459916-56-2 | 98.5% | 353.85 g/mol | C14H12ClN3O2S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000286978.png-250.jpg)
Medchemexpress LLC 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl-thiazolo[4,5-d]pyrimidine-2-thione | 2459916-56-2 | 98.5% | 353.85 g/mol | C14H12ClN3O2S2 | 10 MG
CDK1/Cyc B-IN-1 is a small-molecule inhibitor selective for the CDK1-cyclin B kinase complex. It inhibits CDK1-cyclin B activity (reported IC50 ≈97 nM) and induces G2/M cell-cycle arrest and apoptosis in cancer cell lines. The compound is supplied as a solid with high purity and is used in biochemical and cellular studies of cell-cycle regulation.
- Selective CDK1-cyclin B inhibitor with reported IC50 ≈97 nM.
- Induces G2/M cell-cycle arrest and apoptosis in cell lines.
- Suitable for biochemical kinase assays and cell-based studies.
- High supplied purity for reproducible results.
- Soluble in DMSO at 100 mg/mL; use newly opened DMSO.
- Stable as a powder under recommended cold storage conditions.
Medchemexpress LLC Anti-Mouse Human Mac 1mg | 1mg
Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is a rat-derived anti-mouse/human Mac-2/Galectin-3 IgG2a monoclonal antibody Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) significantly inhibits IL-6 expression (inhibition rates 34 7% and 55 3%) Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is often used for immunoprecipitation western blot immunofluorescence and flow cytometry[1][2][3][4]
Medchemexpress LLC CMP-sialic acid sodium salt | 1007117-62-5 | MFCD00151579 | 90.8% | 636.43 g/mol | C20H30N4NaO16P | 5 MG
CMP-Sialic acid sodium salt is a nucleotide sugar involved in the biosynthesis of sialic acid. It functions as an allosteric inhibitor of UDP-GlcNAc 2-epimerase and provides a substrate for Golgi sialyltransferases, making it useful for enzymatic sialylation and studies of glycan modification in biochemical research.
- Provides substrate activity for Golgi sialyltransferases.
- Acts as an allosteric inhibitor of UDP-GlcNAc 2-epimerase.
- Supports enzymatic sialylation and glycan modification studies.
- Supplied as a solid, white to off-white, with defined storage stability.
- Available in small research-scale quantities for laboratory use.
Sigma Aldrich Fine Chemicals Biosciences Sialic Acid Quantitation K
The Sialic Acid Quantitation Kit provides a rapid and accurate determination of total N-acetylneuraminic acid (NANA sialic acid). NANA is released from glycoconjugates using neuraminidase. The kit uses alpha(2-3 6 8 9) neuraminidase to cleave all NANA linkages including alpha(2-8) and alpha(2-9) linkages as well as branched NANA for the most accurate determination of total sialic acid content.
Medchemexpress LLC IL-18RAP Rhesus Mac 5ug | 5ug
IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators regulation of the cytotoxic activity of NK cells and T cells and differentiation and activation of both Th1 and Th2 cells IL-18 signals through its specific cell surface receptor IL-18R which comprises two subunits IL-18R and IL-18R beta IL-18 forms a signalling complex with the IL-18 receptor (R ) and (R ) chains at the plasma membrane which induces multiple inflammatory cytokines[2] IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6 which phosphorylates nuclear factor k - inducing kinase with subsequent activation of NF- k [3] IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice[4] IL-18RAP Protein Rhesus Macaque (HEK293 His) is a recombinant protein with a His label that consists of 357 amino acids (M1-R356) and is produced by HEK293 cells