Sugar alcohols
Medchemexpress LLC Sorbitol dehydrogenase-IN-1 | 300551-49-9 | MFCD05260911 | 98.7% | 343.43 | C17H25N7O | 25 MG
Sorbitol dehydrogenase-IN-1 is a potent, orally active sorbitol dehydrogenase inhibitor used for biochemical and pharmacological research, including studies of the polyol pathway and diabetes-related complications. It is supplied as a research small-molecule powder with multiple pack sizes for flexible dosing.
- Low-nanomolar potency (IC50 ≈ 4-5 nM) against human and rat sorbitol dehydrogenase.
- Suitable for in vitro and in vivo studies of sorbitol dehydrogenase activity and related metabolic pathways.
- High purity for research applications (manufacturer lists purity ~98.7%).
- Well characterized: CAS 300551-49-9, formula C17H25N7O, molecular weight ~343.43 g·mol-1.
Apexbio Technology LLC D-Sorbitol 98201-93-5 10mM (in 1mL DMSO)
D-Sorbitol is a polyhydric sugar alcohol widely used as an osmotic stabilizer in biological and pharmaceutical research. D-Sorbitol exerts its biological activity primarily through inducing hyperosmotic stress conditions at the cellular level, thereby facilitating the study of osmoregulation mechanisms, stress-responsive signaling pathways, and protein stabilization strategies. As a chemical reagent, it serves as a substrate to analyze enzyme kinetics involving aldose reductase and sorbitol dehydrogenase in metabolic research protocols. Based on these properties, D-Sorbitol holds research potential in cell isolation, tissue culture, studies of the polyol pathway, diabetic complications, and energy balance assays.
