An intermediate active metabolite of fludarabine phosphate inhibits the proliferation of RPMI-8226 MM.1S and MM.1R multiple myeloma cells (IC50s 1.54 13.48 and 33.79 UM respectively) increases Bax levels and decreases Bid XIAP and survivin levels in RPMI-8226 cells at 2 Ug/ml an inhibitor of SARS-CoV-2 RdRp (EC50 1.06 UM) completely inhibits DNA synthesis in an SA-NH murine sarcoma model at 200 mg/kg reduces tumor growth in an RPMI-8226 mouse xenograft model at 40 mg/kg reduces tumor growth in an L1210 murine leukemia model