Eicosanoids

Signaling molecules made by the enzymatic or non-enzymatic oxidation of arachidonic acid or other polyunsaturated fatty acids (PUFAs) that are also 20 carbon units in length.

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Cayman Chemical 13 14dIhydro15keto Prostag 1mg

A metabolite of PGE2; does not bind effectively to EP2 and EP4 in CHO cells (Kis = 12 and 57 µM, respectively) or induce adenylate cyclase activity in CHO cells expressing these receptors (EC50s = >18 and >38 µM, respectively); levels are increased in maternal plasma in the third trimester of pregnancy and in women during and immediately after labor and delivery; levels are decreased in tumor tissue isolated from patients with NSCLC

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Cayman Chemical 15-keto ProstaglndIn F2a 1mg

First metabolite of PGF2α in the 15-hydroxy PGDH pathway; a critical component in the goldfish and Atlantic salmon postovulatory pheromone

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Cayman Chemical 11-ProstaglndIn E1 10mg

11β-PGE1 is an epimerized form of PGE1 at the C-11 position. 11β-PGE1 is a less potent isomer of PGE1. It is 13% and 3.6% as potent as PGE1 in contracting the rat uterus and guinea pig ileum, respectively.{4158}