Fatty acid esters
Medchemexpress LLC Monomethyl auristatin E | 474645-27-7 | MFCD22124498 | ≥98.0% | 1300.64 g/mol | C68H107N9O15 | 10 MG
Monomethyl auristatin E (MMAE) (GMP) is a GMP-grade cytotoxic agent that inhibits tubulin polymerization and is intended for research and development applications, including in vitro cytotoxicity assays and conjugation workflows. Supplied as a solid powder with high purity, it is suitable for laboratory workflows that require GMP-grade material.
- High purity ≥98% (HPLC).
- Potent tubulin polymerization inhibitor with low-nanomolar cellular activity.
- Supplied as a solid powder suitable for conjugation workflows and assays.
- Storage: powder -80°C for long term, -20°C for short term.
- Available in small vial sizes appropriate for R&D use.
- CAS number 474645-27-7 provided for unambiguous identification.
Chem-Impex International, Inc. 5-Bromovaleric acid methyl ester | MFCD00000265 | 5G
5-Bromovaleric acid methyl ester, MFCD00000265, 5G
Medchemexpress LLC Pimelic acid monoethyl ester | 33018-91-6 | MFCD00014383 | 99.1% | 188.22 g/mol | C9H16O4 | 10 G
Monoethyl pimelate is a small-molecule PROTAC linker and alkyl/ether building block used in medicinal chemistry for the synthesis of targeted protein degraders. It is the monoethyl ester of pimelic acid (CAS 33018-91-6), with formula C9H16O4 and molar mass 188.22 g/mol.
- Used as a PROTAC linker in degrader synthesis
- Suitable for synthesis of BCL-XL PROTAC degraders
- Molecular formula C9H16O4 and molecular weight 188.22 g/mol
- High chemical purity (~99.1%)
- Available as a 10 g pack for laboratory use
- Acts as an alkyl/ether building block for esterification chemistry
Medchemexpress LLC Ethyl linoleate (Linoleic acid ethyl ester) | 544-35-4 | MFCD00009575 | 99.7% | 308.50 | 500 MG
Ethyl linoleate is an orally active unsaturated fatty acid, also known as Linoleic Acid ethyl ester. It functions by inhibiting the Akt/GSK3β/β-catenin signaling pathway and the activation of NF-κB. This compound induces heme oxygenase-1 and inhibits tyrosinase, contributing to its whitening and anti-inflammatory effects. It also promotes compound absorption and significantly influences atherosclerosis. Ethyl linoleate is utilized in inflammatory disease research and has applications in cosmetics.
- Inhibits Akt/GSK3β/β-catenin signaling pathway.
- Inhibits activation of NF-κB.
- Induces heme oxygenase-1.
- Inhibits tyrosinase, contributing to whitening and anti-inflammatory effects.
- Promotes compound absorption.
- Significantly influences atherosclerosis.
- Utilized in inflammatory disease research.
- Applications in cosmetics.