Fatty alcohol esters
Medchemexpress LLC L-NMMA acetate | 53308-83-1 | 99.0% | 248.28 | 100 MG
L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 μM, respectively.
- Functions as a nitric oxide synthase inhibitor.
- Inhibits all NOS isoforms (NOS1, NOS2, and NOS3).
- Demonstrates Ki values for nNOS (rat) of approximately 0.18 μM.
- Demonstrates Ki values for eNOS (human) of approximately 0.4 μM.
- Demonstrates Ki values for iNOS (mouse) of approximately 6 μM.
Apexbio Technology LLC Megestrol Acetate 595-33-5 10mM (in 1mL DMSO)
Megestrol Acetate (CAS 595-33-5) is a synthetic progestin utilized to downregulate nuclear and cytoplasmic androgen receptor activity It modulates hormone receptor-mediated processes thereby impacting cellular metabolic and signaling pathways Megestrol Acetate exerts its biological activity primarily by inducing apoptosis and disrupting cell cycle progression In in vitro studies using HepG2 cell lines Megestrol Acetate demonstrates proliferation inhibition with an IC50 value of approximately 260 M Based on these pharmacological properties Megestrol Acetate holds research potential in studies of cancer cachexia hepatocellular carcinoma and the investigation of tumor growth mechanisms
Medchemexpress LLC Larazotide (acetate) | 881851-50-9 | MFCD31630844 | 99.2% | 785.89 g/mol | C34H59N9O12 | 1 ML
Larazotide (acetate) is a synthetic peptide used in research to modulate tight junctions and reduce intestinal permeability. It is applied in studies of celiac disease, intestinal barrier function, and related infection models. The product is supplied with molecular data and solubility guidance to support experimental preparation and formulation of stock solutions.
- Synthetic peptide zonulin antagonist.
- Intended for research use only.
- Includes molecular weight and formula data.
- Provides solubility and stock solution preparation guidance.
- Available in multiple small-scale packaging sizes for laboratory use.
Medchemexpress LLC Vapreotide acetate | 849479-74-9 | 98.2% | 1191.42 | 10 MG
Vapreotide acetate is a neurokinin-1 (NK1) receptor antagonist with an IC50 of 330 nM. It is intended for research use only.
- Attenuates Substance P (SP)-triggered intracellular calcium increases and NF-κB activation.
- Inhibits SP-induced IL-8 and MCP-1 production.
- Inhibits HIV-1 infection of human MDM in vitro.
- Inhibits GH-, PRL, and/or alpha-subunit release by human GH-secreting pituitary adenoma cells.
- Exhibits affinities for SSTR2, -3, and -5.
- Reduces tumor volumes and weights in androgen-independent prostate cancer xenografts.
- Decreases collateral circulation blood flow in cirrhosis and attenuates its development.
Medchemexpress LLC Ornipressin acetate | 914453-98-8 | 99.6% | 1042.19 | 100 MG
Ornipressin (POR-8) acetate is a potent vasoconstrictor, hemostatic, and renal agent. It acts as a vasopressin agonist specific for the V1 receptor. It is suitable for laboratory research use.
- Can be used as a local vasoconstrictor
- Reverses hypotension associated with combined general/epidural anesthesia
- Has antidiuretic activity
- Decreases renal vascular resistance
- Increases renal blood flow in renal failure models
Medchemexpress LLC SPR741 acetate | 99.4% | 1052.18 | 100 MG
SPR741 acetate is a cationic peptide derived from polymyxin B, functioning as a potentiator molecule. It enhances the permeability of the outer membrane of Gram-negative bacteria, making it useful for treating severe Gram-negative bacterial infections and inhibiting multidrug-resistant Gram-negative bacteria. While it lacks significant antibacterial activity on its own, it increases the accumulation of co-administered antibiotics inside the pathogen and has an improved safety profile compared to polymyxin B.
- Enhances permeability of Gram-negative bacterial outer membrane
- Useful for treating severe Gram-negative bacterial infections
- Inhibits multidrug-resistant Gram-negative bacteria
- Broadens activity spectrum of antibiotics when combined
- Potentiates antibiotics that are substrates of the AcrAB-TolC efflux pump
- Improved safety profile compared to polymyxin B
Medchemexpress LLC L-NMMA acetate | 53308-83-1 | MFCD00083440 | 99.0% | 248.28 | 50 MG
L-NMMA acetate is a nitric oxide synthase inhibitor that targets all NOS isoforms, including NOS1, NOS2, and NOS3. Its Ki values are approximately 0.18 μM for nNOS (rat), 0.4 μM for eNOS (human), and 6 μM for iNOS (mouse). This product is intended for research use only and is not sold to patients.
- Nitric oxide synthase inhibitor of all NOS isoforms (NOS1, NOS2, and NOS3).
- High purity of 99.0%.
- Available in various quantities from 1 mg to 100 mg for purchase, with larger quantities available via quote.
- Product information includes data sheet, COA, SDS, and handling instructions.
Medchemexpress LLC Rusalatide acetate (TP508 amide acetate) | 875455-82-6 | 98.1% | 2371.50 Da | C99H151N29O37S | 10 MG
Rusalatide acetate (TP508 amide acetate) is a 23-amino-acid regenerative peptide for research use that mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity. It is supplied as a lyophilized powder intended for experimental applications in tissue regeneration and radioprotection studies.
- Regenerative peptide that activates stem cells.
- Mitigates radiation-induced gastrointestinal damage and preserves crypt integrity.
- Defined 23-amino-acid sequence with amide C-terminus.
- Reported high purity (about 98.1%).
- Stable when stored frozen and protected from moisture and light.
Medchemexpress LLC CBP-501 (acetate) | 1929.06 (free base) | 1 MG
CBP-501 acetate is a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate. It inhibits the activity of multiple Ser216-specific kinases, including MAPKAP-K2, C-Tak1, CHK1, and CHK2. It is used for various types of cancer and enhances the cytotoxicity of CDDP and Bleomycin against cancer cells both in vitro and in vivo.
- Inhibits MAPKAP-K2 with an IC50 of 0.9 μM
- Inhibits C-Tak1 with an IC50 of 1.4 μM
- Inhibits Chk1 with an IC50 of 3.4 μM
- Inhibits Chk2 with an IC50 of 6.5 μM
- Stable for 2 years at -80°C as powder
- Stable for 1 year at -20°C as powder
- Stable for 6 months at -80°C in solvent
- Stable for 1 month at -20°C in solvent
- Enhances cytotoxicity of CDDP and Bleomycin
Hampton Research HR2-406-15/Detergent Screen #15 (B3), 0.5 ml - n-Tridecyl-b-D-maltoside
HR2-406-15/Detergent Screen #15 (B3), 0.5 ml - n-Tridecyl-b-D-maltoside. Please note items from this supplier are non-returnable.
Sigma Aldrich Fine Chemicals Biosciences Citronellyl acetate >=95%, FCC, FG | 150-84-5 | MFCD00015039 | 20KG
Citronellyl acetate >=95%, FCC, FG | Purity: >=95% | Mol Wt: 198.3 | 150-84-5 | MFCD00015039 | 20KG
Medchemexpress LLC Delmitide acetate 10mg | 501019-16-5 | 10MG
Delmitide (RDP58) acetate is an orally active d-isomer decapeptide with potent anti-inflammatory activity Delmitide acetate inhibits production of TNF- IFN- and interleukin (IL)-12 and up-regulates heme oxygenase 1 activity Delmitide acetate can be used for the research of ulcerative colitis[1 [2