(Rac)-sn-Glycerol 3-phosphate is an a-site substrate analogue. It binds to the a-site, strongly inhibiting the reaction rate of indole and nucleophilic indole analogues with E(A-A). It is a phosphorylated derivative of glycerol, produced as an intermediate in the glycolysis pathway. This compound binds to the α subunit of tryptophan synthase, regulating tryptophan synthesis through allosteric inhibition. It also provides microorganisms with advantages in nutrient-lacking environments as sources of phosphorus, carbon, and energy, and can be used for microbial cultivation. Additionally, it binds to metal ions, forming insoluble phosphate minerals, and can be utilized for in situ bioremediation to reduce environmental pollution.
- Endogenous metabolite
- A-site substrate analogue
- Regulates tryptophan synthesis
- Can be used for microorganisms cultivation
- Can be used for in situ bioremediation