Sphingolipids
Cayman Chemical C162 S-hydroxy CeramIde 25mg
A synthetic ceramide; has no effect on C6 glioma cell viability at concentrations up to 20 µM
Medchemexpress LLC C2 ceramide (N-acetylsphingosine) | 3102-57-6 | MFCD07374281 | 99.9% | 341.53 g/mol | C20H39NO3 | 25 MG
C2 ceramide (N-acetylsphingosine) is a short-chain ceramide research reagent used to modulate ceramide signaling and study cellular responses. It is used in biochemical and cell biology assays to probe protein phosphatase activity, mitochondrial function, and processes such as apoptosis, autophagy, and epidermal barrier behavior.
- Activates protein phosphatases PP1 and PP2A for signaling studies.
- Induces apoptosis and autophagy in cellular models.
- Affects mitochondrial respiratory chain for metabolic research.
- High-purity solid suitable for biochemical and cell-based assays.
- Stable when stored sealed at -20°C; follow solvent storage guidelines for solutions.
- Applicable to skin barrier and epidermal function research.
Medchemexpress LLC C6 Ceramide | 124753-97-5 | 99.8% | 397.63 | 1 MG
C6 Ceramide | 124753-97-5 | 99.8% | 397.63 | 1 MG
Medchemexpress LLC N-Octanoyl-D-erythro-sphingosine | 74713-59-0 | 98.0% | 425.69 | 10 G
C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. It possesses anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections and induces slight activation of protein kinase (PKC) in vitro.
- Cell-permeable analog of naturally occurring ceramides
- Exhibits anti-proliferation properties
- Acts as a potent chemotherapeutic agent
- Stimulates dendritic cells to promote T cell responses upon virus infections
- Induces slight activation of protein kinase (PKC) in vitro
Medchemexpress LLC C20 Ceramide (N-Arachidoyl-D-sphingosine) | 7344-02-7 | 99.1% | 594.01 | 25 MG
C20 Ceramide (N-Arachidoyl-D-sphingosine) is a natural 20:0 ceramide and a N-acylsphingosine in which the ceramide N-acyl group is specified as eicosanoyl. C20 Ceramide acts as a key signal molecule mediating biological processes. It is for research use only and not sold to patients.
- Natural 20:0 ceramide
- N-acylsphingosine with eicosanoyl N-acyl group
- Acts as a key signal molecule
- Mediates cell growth, differentiation, senescence, and apoptosis
- For research use only
Cayman Chemical C12 NBD Ceramide d18 1 12 0
C12 NBD ceramide (d18:1/12:0) is a long-chain fluorescent ceramide analog that can be used for the measurement of alkaline and neutral ceramidase activity.{14063} It is hydrolyzed efficiently by alkaline ceramidase from P. aeruginosa and by neutral ceramidase from mouse liver. In addition, alkaline and neutral ceramidases from a variety of mammalian cell lines also hydrolyze C12 NBD ceramide (d18:1/12:0). Acid ceramidase does not appear to utilize C12 NBD ceramide (d18:1/12:0) as a substrate. The possibility exists forC12 NBD ceramide (d18:1/12:0) to also be applied to the measurement of ceramide kinase and/or sphingomyelin synthase activity.
Medchemexpress LLC N-Arachidoyl-D-sphingosine | 7344-02-7 | 99.1% | 594.01 | 50 MG
C20 Ceramide, also known as N-Arachidoyl-D-sphingosine, is a natural 20:0 ceramide. This N-acylsphingosine has its N-acyl group specified as eicosanoyl, functioning as a vital signal molecule.
- Mediates cell growth
- Influences cell differentiation
- Involved in cell senescence
- Regulates apoptosis
Medchemexpress LLC 4,7,10,13,16,19-Docosahexaenamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen -1-yl]- | 218608-43-6 | 98.7% | 609.96 | 25 MG
DHA Ceramide is a light yellow to yellow solid with a molecular weight of 609.96. It has a purity of 98.65% by HPLC and is tested to comply with given specifications. This product is for research use only.
- Light yellow to yellow solid
- For research use only
- Store at -20°C, protected from light, and under nitrogen
- Tested and complies with given specifications
Medchemexpress LLC C26 Sphingomyelin (d18:1/26:0)-d4 | 98.0% | 847.32 | 500 UG
C26 Sphingomyelin (d18:1/26:0)-d4 | 98.0% | 847.32 | 500 UG
Medchemexpress LLC Sphingomyelin | 85187-10-6 | ≥99.0% | 50 MG
Sphingomyelin is a eukaryotic sphingolipid and a major constituent of cell membranes, particularly abundant in the myelin sheath that surrounds neuronal axons. It plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann-Pick disease.
- Major constituent of cell membranes
- Abundant in the myelin sheath
- Plays a role in cell processes
- Regulates inflammatory responses
- Involved in signal transduction
- Metabolism associated with central nervous system diseases and Niemann-Pick disease
Cayman Chemical C20 Ceramide d18 1 20 0
A natural 20:0 ceramide that is abundant in the brain; synthesized de novo by ceramide synthases 1 and 2
Cayman Chemical C20 Ceramide d18 1 20 0
A natural 20:0 ceramide that is abundant in the brain; synthesized de novo by ceramide synthases 1 and 2