Steroids and derivatives
Selleck Chemical LLC Dexamethasone Sodium Phosphate S4028-1g
Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects
Apexbio Technology LLC Dexamethasone (DHAP) 50-02-2 10mM (in 1mL DMSO)
Dexamethasone (DHAP) is a synthetic glucocorticoid commonly utilized in biomedical research due to its potent anti-inflammatory function and immunomodulatory effects It exerts its mechanism through glucocorticoid receptor-mediated transcriptional modulation resulting in reduced transcriptional activity of NF- B signaling pathways in dendritic cells (DC) thus inhibiting DC maturation and activation This compound is frequently employed in experiments investigating immune regulation inflammation and cell differentiation processes including induction of differentiation in human mesenchymal stem cells (MSCs) Additionally dexamethasone is used in cancer cell biology research as it promotes autophagy in acute lymphoblastic leukemia-derived cell lines Reported IC50 values for dexamethasone-mediated inhibition of cellular inflammation responses typically range from 2 50 nM depending on specific cellular models and experimental conditions
Cayman Chemical 2-bromo 17-EstradIol 10mg
A synthetic steroid and inhibitor of estrogen 2-hydroxylase; inhibits estrogen 2-hydroxylase in rat liver microsomes at 50 and 100 µM; prevents estrogen-induced inhibition of apomorphine-induced climbing behavior in mice at 5 mg/kg
Apexbio Technology LLC Fluorometholone Acetate 3801-06-7 50mg
Fluorometholone Acetate (CAS 3801-06-7) is a synthetic glucocorticoid corticosteroid designed for the modulation of inflammatory responses Acting through binding to the glucocorticoid receptor it regulates the transcription of anti-inflammatory proteins while suppressing pro-inflammatory gene expression This compound is extensively utilized in ophthalmic research for modeling and investigating steroid-responsive inflammatory processes in ocular tissues Its application facilitates the study of corticosteroid-mediated pathways in eye inflammation and aids in the evaluation of anti-inflammatory interventions in preclinical settings
Cayman Chemical TaurolIthocholIc ACD MaxSpec
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
Medchemexpress LLC 9-fluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate | 338-98-7 | MFCD00468096 | 98.6% | C23H29FO6 | 10MG
Isoflupredone acetate is a synthetic corticosteroid acetate used as an analytical reference standard for research and analytical applications such as HPLC, GC, and MS. Supplied as a high-purity solid, it is intended for assay development, calibration, and method validation in pharmaceutical and veterinary research.
- Analytical standard for HPLC, GC, and MS
- High reported purity (~98.5%)
- Suitable for assay development and method validation
- Available in small milligram pack sizes for reference use
- Provided with batch-specific certificate of analysis
Cayman Chemical 25-hydroxy VItamIn D3 1mg
An intermediate in the pathway leading to the production of 1,25-dihydroxy vitamin D3; plasma or serum levels are commonly used as an indicator of an individual’s vitamin D status