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Nucleoside and nucleotide analogues

Nucleosides and nucleotides containing a nucleic acid analogue (a compound structurally similar to naturally occurring RNA or DNA); analogous nucleobases typically possess, among other things, different base pairing and base stacking properties.

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1

Medchemexpress LLC Lamivudine (BCH-189) | 134678-17-4 | 99.9% | 1 ML
SDP

Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV reverse transcriptase 1/2 and the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS.

  • Used in studies involving VSMCs for staining and calcium content analysis.
  • Applied in Western blot analysis for various protein markers in VSMCs.
  • Utilized in animal models to study serum creatinine levels and aortic calcification.
  • Suitable for immunohistochemical staining and analysis of osteogenic and contractile phenotypic markers.

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2

Medchemexpress LLC Rp-cAMPS sodium salt | 142439-94-9 | 99.7% | 367.25 | C10H11N5NaO5PS | 1 MG
SDP

Rp-cAMPS sodium salt is a cyclic AMP (cAMP) analog that functions as a potent, competitive antagonist of cAMP-dependent protein kinase A (PKA) I and II. Supplied as the sodium salt for research use, it is a white-to-pink solid with high purity and is used to inhibit cAMP-mediated PKA activation in biochemical and cell signaling studies.

  • Potent, competitive antagonist of cAMP-dependent PKA I and II.
  • High purity (99.7%) suitable for research applications.
  • Available in small solid quantities for precise dosing.
  • Stable under recommended storage when sealed and protected from moisture and light.
  • Compatible with biochemical and cell signaling assays to study cAMP pathways.

ENCOMPASS_PREFERRED
3

Medchemexpress LLC Rp-cAMPS sodium salt | 142439-94-9 | 99.7% | 367.25 | C10H11N5NaO5PS | 5 MG
SDP

Rp-cAMPS sodium salt is a cAMP analog that competitively antagonizes cAMP-dependent protein kinase A (PKA) I and II and is resistant to hydrolysis by phosphodiesterases, intended for biochemical and cell signaling research applications.

  • High purity (≈99.7%) suitable for biochemical assays.
  • Molecular formula C10H11N5NaO5PS and molecular weight 367.25 g/mol.
  • Resistant to hydrolysis by phosphodiesterases.
  • Reported Ki values ~6.05 μM (PKA I) and ~9.75 μM (PKA II).
  • Solid, white to pink appearance; available as solid or solution (10 mM in DMSO).
  • Storage: -20°C sealed; in solvent -80°C (6 months) or -20°C (1 month).

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