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Nucleoside and nucleotide analogues

Nucleosides and nucleotides containing a nucleic acid analogue (a compound structurally similar to naturally occurring RNA or DNA); analogous nucleobases typically possess, among other things, different base pairing and base stacking properties.
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1 – 14 of 14 results
1

Lamivudine Impurity Standard, British Pharmacopoeia (BP) Reference Standard, MilliporeSigma™ Supelco™

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

2

Dorzolamide Impurity D, British Pharmacopoeia (BP) Reference Standard, MilliporeSigma™ Supelco™

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

3

Lamivudine, 98%

CAS: 134678-17-4 Molecular Formula: C8H11N3O3S Molecular Weight (g/mol): 229.26 InChI Key: JTEGQNOMFQHVDC-NKWVEPMBSA-N Synonym: lamivudine,epivir,zeffix,heptovir,epivir-hbv,hepitec,heptodin,2',3'-dideoxy-3'-thiacytidine,lamivir,3tc PubChem CID: 60825 ChEBI: CHEBI:63577 IUPAC Name: 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one SMILES: C1C(OC(S1)CO)N2C=CC(=NC2=O)N

PubChem CID 60825
CAS 134678-17-4
Molecular Weight (g/mol) 229.26
ChEBI CHEBI:63577
SMILES C1C(OC(S1)CO)N2C=CC(=NC2=O)N
Synonym lamivudine,epivir,zeffix,heptovir,epivir-hbv,hepitec,heptodin,2',3'-dideoxy-3'-thiacytidine,lamivir,3tc
IUPAC Name 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
InChI Key JTEGQNOMFQHVDC-NKWVEPMBSA-N
Molecular Formula C8H11N3O3S
4

Lamivudine 98.0+%, TCI America™
SDP

CAS: 134678-17-4 Molecular Formula: C8H11N3O3S Molecular Weight (g/mol): 229.254 MDL Number: MFCD00869739 InChI Key: JTEGQNOMFQHVDC-NKWVEPMBSA-N Synonym: lamivudine,epivir,zeffix,heptovir,epivir-hbv,hepitec,heptodin,2',3'-dideoxy-3'-thiacytidine,lamivir,3tc PubChem CID: 60825 ChEBI: CHEBI:63577 IUPAC Name: 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one SMILES: C1C(OC(S1)CO)N2C=CC(=NC2=O)N

PubChem CID 60825
CAS 134678-17-4
Molecular Weight (g/mol) 229.254
ChEBI CHEBI:63577
MDL Number MFCD00869739
SMILES C1C(OC(S1)CO)N2C=CC(=NC2=O)N
Synonym lamivudine,epivir,zeffix,heptovir,epivir-hbv,hepitec,heptodin,2',3'-dideoxy-3'-thiacytidine,lamivir,3tc
IUPAC Name 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
InChI Key JTEGQNOMFQHVDC-NKWVEPMBSA-N
Molecular Formula C8H11N3O3S
5

Emtricitabine 98.0+%, TCI America™
SDP

CAS: 143491-57-0 Molecular Formula: C8H10FN3O3S Molecular Weight (g/mol): 247.244 MDL Number: MFCD00870151 InChI Key: XQSPYNMVSIKCOC-NTSWFWBYSA-N PubChem CID: 60877 ChEBI: CHEBI:31536 IUPAC Name: 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one SMILES: C1C(OC(S1)CO)N2C=C(C(=NC2=O)N)F

PubChem CID 60877
CAS 143491-57-0
Molecular Weight (g/mol) 247.244
ChEBI CHEBI:31536
MDL Number MFCD00870151
SMILES C1C(OC(S1)CO)N2C=C(C(=NC2=O)N)F
IUPAC Name 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
InChI Key XQSPYNMVSIKCOC-NTSWFWBYSA-N
Molecular Formula C8H10FN3O3S
6

Medchemexpress LLC Lamivudine | 134678-17-4 | 99.9% | 229.26 g/mol | C8H11N3O3S | 10 MG

Analytical reference standard of lamivudine, an orally active nucleoside reverse transcriptase inhibitor, supplied as a 10 mg pack for laboratory reference, assay calibration, and analytical method development. High purity and characterized identity support reliable quantitative analysis.

  • High purity: 99.85% (reported).
  • Intended for analytical and research use.
  • CAS number: 134678-17-4.
  • Molecular formula: C8H11N3O3S.
  • Molecular weight: 229.26 g/mol.

ENCOMPASS_PREFERRED
7

Medchemexpress LLC Rp-cAMPS sodium salt | 142439-94-9 | 99.7% | 367.25 | C10H11N5NaO5PS | 1 MG

Rp-cAMPS sodium salt is a cyclic AMP (cAMP) analog that functions as a potent, competitive antagonist of cAMP-dependent protein kinase A (PKA) I and II. Supplied as the sodium salt for research use, it is a white-to-pink solid with high purity and is used to inhibit cAMP-mediated PKA activation in biochemical and cell signaling studies.

  • Potent, competitive antagonist of cAMP-dependent PKA I and II.
  • High purity (99.7%) suitable for research applications.
  • Available in small solid quantities for precise dosing.
  • Stable under recommended storage when sealed and protected from moisture and light.
  • Compatible with biochemical and cell signaling assays to study cAMP pathways.

ENCOMPASS_PREFERRED
8

Apexbio Technology LLC Lamivudine 134678-17-4 10mM (in 1mL DMSO)

Lamivudine is a nucleoside analog that acts primarily as a reverse transcriptase inhibitor disrupting viral replication by interfering with RNA-dependent DNA polymerase activity It inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with an IC50 value of approximately 0 316 M Lamivudine also suppresses replication of simian retrovirus (SRV-1 and SRV-2) while exhibiting negligible activity on foamy viruses and amphotropic murine leukemia virus (MLV-A) Due to its antiviral mechanism and dual inhibitory effect against both HIV-1 and hepatitis B virus (HBV) lamivudine is frequently utilized in research involving retroviral infection models particularly HIV-1 and HBV coinfection studies to evaluate viral dynamics antiviral efficacy and biochemical responses

ENCOMPASS_PREFERRED
9

eMolecules​ Medchem Express / Rp-cAMPS (sodium salt) / 1mg / 632433127 / HY-100530D / / 142439-94-9 / [null] / 367.250 / C10H11N5NaO5PS

Medchem Express / Rp-cAMPS (sodium salt) / 1mg / 632433127 / HY-100530D / / 142439-94-9 / [null] / 367.250 / C10H11N5NaO5PS

ENCOMPASS_PREFERRED
10

Apexbio Technology LLC Lamivudine 134678-17-4 50mg

Lamivudine is a nucleoside analog that acts primarily as a reverse transcriptase inhibitor disrupting viral replication by interfering with RNA-dependent DNA polymerase activity It inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with an IC50 value of approximately 0 316 M Lamivudine also suppresses replication of simian retrovirus (SRV-1 and SRV-2) while exhibiting negligible activity on foamy viruses and amphotropic murine leukemia virus (MLV-A) Due to its antiviral mechanism and dual inhibitory effect against both HIV-1 and hepatitis B virus (HBV) lamivudine is frequently utilized in research involving retroviral infection models particularly HIV-1 and HBV coinfection studies to evaluate viral dynamics antiviral efficacy and biochemical responses

ENCOMPASS_PREFERRED
11

Medchemexpress LLC Rp-cAMPS sodium salt | 142439-94-9 | 99.7% | 367.25 | C10H11N5NaO5PS | 5 MG

Rp-cAMPS sodium salt is a cAMP analog that competitively antagonizes cAMP-dependent protein kinase A (PKA) I and II and is resistant to hydrolysis by phosphodiesterases, intended for biochemical and cell signaling research applications.

  • High purity (≈99.7%) suitable for biochemical assays.
  • Molecular formula C10H11N5NaO5PS and molecular weight 367.25 g/mol.
  • Resistant to hydrolysis by phosphodiesterases.
  • Reported Ki values ~6.05 μM (PKA I) and ~9.75 μM (PKA II).
  • Solid, white to pink appearance; available as solid or solution (10 mM in DMSO).
  • Storage: -20°C sealed; in solvent -80°C (6 months) or -20°C (1 month).

ENCOMPASS_PREFERRED
12

Selleck Chemical LLC Lamivudine S1706-1g

Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor used for treatment of chronic HBV and HIV/AIDS It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase

ENCOMPASS_PREFERRED
13

Selleck Chemical LLC Lamivudine S1706-10mM/1mL

Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor used for treatment of chronic HBV and HIV/AIDS It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase

ENCOMPASS_PREFERRED
14

TARGETMOL CHEMICALS INC Lamivudine 500MG

Also available in 1 mL, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease. Purity 99.56%

ENCOMPASS_PREFERRED