Pyridine nucleotides
Apexbio Technology LLC Nicotinamide(Synonyms: Nicotinic acid amide, Vitamin B3 amide, Niacinamide, Pyridine-3-carboxamide, 3-Pyridinecarboxamide), 10mM (in 1mL DMSO), CAS: 98-92-0.
Nicotinamide (CAS 98-92-0) is a small-molecule inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) an enzyme critical in DNA repair pathways Under pathological conditions such as ischemia or trauma PARP-1 hyperactivation depletes cellular NAD triggering neuronal cell death In vitro studies indicate that transporter-mediated uptake of nicotinamide confers protection against PARP-1-induced astrocyte injury In vivo studies in diabetic rat models demonstrate that nicotinamide administration normalizes hepatic antioxidant enzymes reducing oxidative stress Clinical trials have shown dose-dependent upregulation of frataxin expression following sustained nicotinamide treatment suggesting therapeutic potential in disorders like Friedreich s ataxia
eMolecules 98-92-0 | Nicotinamide | Oakwood Chemicals | MFCD00006395 | 122.127 | C6H6N2O | 99.000 | NC(=O)c1cccnc1 | 1kg | 480163728
Nicotinamide | Oakwood Chemicals | 98-92-0 | MFCD00006395 | 122.127 | C6H6N2O | 99.000 | NC(=O)c1cccnc1 | 1kg | 480163728
Sigma Aldrich Fine Chemicals Biosciences beta Nicotinamide adenine250MG
beta Nicotinamide adenine250MG
eMolecules 1094-61-7 | ?-Nicotinamide mononucleotide | AA Blocks LLC | MFCD00038748 | 334.221 | C11H15N2O8P | 0.000 | NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O | 5g | 435952318
?-Nicotinamide mononucleotide | AA Blocks LLC | 1094-61-7 | MFCD00038748 | 334.221 | C11H15N2O8P | 0.000 | NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O | 5g | 435952318
Apexbio Technology LLC Nicotinamide(Synonyms: Nicotinic acid amide, Vitamin B3 amide, Niacinamide, Pyridine-3-carboxamide, 3-Pyridinecarboxamide), 1g, CAS: 98-92-0.
Nicotinamide (CAS 98-92-0) is a small-molecule inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) an enzyme critical in DNA repair pathways Under pathological conditions such as ischemia or trauma PARP-1 hyperactivation depletes cellular NAD triggering neuronal cell death In vitro studies indicate that transporter-mediated uptake of nicotinamide confers protection against PARP-1-induced astrocyte injury In vivo studies in diabetic rat models demonstrate that nicotinamide administration normalizes hepatic antioxidant enzymes reducing oxidative stress Clinical trials have shown dose-dependent upregulation of frataxin expression following sustained nicotinamide treatment suggesting therapeutic potential in disorders like Friedreich s ataxia
C1OC(COP(O)([O-])=O)C(O)C1O | 250mg | 490843765](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000130635.jpg-250.jpg)
eMolecules 1094-61-7 | b-Nicotinamide mononucleotide | Chem-Impex334.221 | C11H15N2O8P | 99.000 | NC(=O)c1ccc[n+](c1)C1OC(COP(O)([O-])=O)C(O)C1O | 250mg | 490843765
b-Nicotinamide mononucleotide | Chem-Impex | 1094-61-7334.221 | C11H15N2O8P | 99.000 | NC(=O)c1ccc[n+](c1)C1OC(COP(O)([O-])=O)C(O)C1O | 250mg | 490843765
Sigma Aldrich Fine Chemicals Biosciences alpha-Nicotinamide adenine dinucleotide from Saccharomyces cerevisiae, <=1% beta-isomer, >=95% | 7298-93-3 | MFCD00134828 | 10MG
alpha-Nicotinamide adenine dinucleotide from Saccharomyces cerevisiae, <=1% beta-isomer, >=95% | Purity: >=95% | Mol Wt: 663.43 | 7298-93-3 | MFCD00134828 | 10MG
Medchemexpress LLC Glutathione oxidized-13C4,15N2 | 1416898-83-3 | 99.80% | 1 MG
Glutathione oxidized-13C4,15N2 is the 13C and 15N labeled Glutathione oxidized. This compound is produced by the oxidation of glutathione. The detoxification of reactive oxygen species is accompanied by the production of glutathione oxidized. It can be used for the research of sickle cells and erythrocytes.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into molecules for quantitation during the development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles.
