Nicotinamide is a form of vitamin B3 (niacin) that inhibits SIRT2 and SIRT1 activity. It increases cellular NAD+, ATP, and ROS levels, and is known to inhibit tumor growth, improve survival, and exhibit anti-HBV activity. It is intended for research use only.
- Inhibits SIRT2 and SIRT1 activity
- Increases cellular NAD+, ATP, and ROS levels
- Inhibits tumor growth and improves survival
- Possesses anti-HBV activity
- Reduces cell number in A375 and SK-MEL-28 cells
- Promotes pancreatic cell differentiation from human embryonic stem cells