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Nicotinamide Riboside Chloride is the chloride salt form of nicotinamide riboside(NR) NR is a new form pyridine-nucleoside of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide(NAD) or NAD Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride Nicotinamide riboside chloride increases NAD[ ] levels and activates SIRT1 and SIRT3 culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities Nicotinamide riboside chloride is used in dietary supplements
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Nicotinamide adenine dinucleotide (NAD CAS number 53-84-9) is a coenzyme involved in oxidation-reduction reactions accepting electrons to form NADH Additionally NAD functions as a substrate in enzymatic processes mediated by poly(ADP-ribose) polymerases sirtuins and cyclic ADP-ribose synthases NAD analogs demonstrate inhibitory activity against CD38-associated NAD glycohydrolase (NADase) with reported IC50 values ranging from 2 mM to 10 mM In biomedical research NAD supplementation is investigated for addressing fatigue and fatigue-associated disorders
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-Nicotinamide adenine dinucleotide (NAD) is an electron carrier and a cofactor. It is ubiquitously found in the living system. NAD contains an adenylic acid and a nicotinamide-5AE-ribonucleotide group linked together by a pyrophosphate moiety. In NAD complexes the enzyme-cofactor interactions are highly conserved.
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This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. for further information and support please go to the website of the issuing Pharmacopoeia.Nicotinamide belongs to the group of water-soluble B vitamins. It is generally formed from nicotinic acid (vitamin B3). It is available in food products and is utilized for the treatment of pellagra psoriasis nbspschizophrenia andnbsptype I diabetes. It is also known for its anti-inflammatory activity.
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β-Nicotinamide-Adenine Dinucleotide, Oxidized Form (β-NAD) is suitable for Enzyme synthesis / Biocatalysis applications. It is also applicable for making Enzyme Multiplied Immunoassay Technique (EMIT), Therapeutic Drug monitoring (TDM) and Blood Glucose reagents.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
β-Nicotinamide-Adenine Dinucleotide, Oxidized Form (β-NAD) is suitable for Enzyme synthesis / Biocatalysis applications. It is also applicable for making Enzyme Multiplied Immunoassay Technique (EMIT), Therapeutic Drug monitoring (TDM) and Blood Glucose reagents.
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Nicotinamide (CAS 98-92-0) is a small-molecule inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) an enzyme critical in DNA repair pathways Under pathological conditions such as ischemia or trauma PARP-1 hyperactivation depletes cellular NAD triggering neuronal cell death In vitro studies indicate that transporter-mediated uptake of nicotinamide confers protection against PARP-1-induced astrocyte injury In vivo studies in diabetic rat models demonstrate that nicotinamide administration normalizes hepatic antioxidant enzymes reducing oxidative stress Clinical trials have shown dose-dependent upregulation of frataxin expression following sustained nicotinamide treatment suggesting therapeutic potential in disorders like Friedreich s ataxia
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Nicotinamide (CAS 98-92-0) is a small-molecule inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) an enzyme critical in DNA repair pathways Under pathological conditions such as ischemia or trauma PARP-1 hyperactivation depletes cellular NAD triggering neuronal cell death In vitro studies indicate that transporter-mediated uptake of nicotinamide confers protection against PARP-1-induced astrocyte injury In vivo studies in diabetic rat models demonstrate that nicotinamide administration normalizes hepatic antioxidant enzymes reducing oxidative stress Clinical trials have shown dose-dependent upregulation of frataxin expression following sustained nicotinamide treatment suggesting therapeutic potential in disorders like Friedreich s ataxia
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More