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Pyridine nucleotides

Small molecules comprising two mononucleotides, adenosine monophosphate (AMP) and nicotinamide mononucleotide (NMN); oxidized and reduced nicotinamide adenine dinucleotides in their unphosphorylated (NAD+ or NADH) and phosphorylated (NADP+ or NADPH) forms.
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1

β-Nicotinamide adenine dinucleotide phosphate, Cell Culture Reagent, MP Biomedicals™

CAS: 53-84-9 Molecular Formula: C21H27N7O14P2 Molecular Weight (g/mol): 663.43 MDL Number: MFCD00150377 InChI Key: BAWFJGJZGIEFAR-WIWLTUSXNA-N Synonym: nicotinamide adenine dinucleotide,nad+,diphosphopyridine nucleotide,nad-oxidized,nicotinamide-adenine dinucleotide,dpn-ox,beta-nicotinamide adenine dinucleotide,dpn+,nad,nad + PubChem CID: 15938971 ChEBI: CHEBI:57540 SMILES: NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O

PubChem CID 15938971
CAS 53-84-9
Molecular Weight (g/mol) 663.43
ChEBI CHEBI:57540
MDL Number MFCD00150377
SMILES NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
Synonym nicotinamide adenine dinucleotide,nad+,diphosphopyridine nucleotide,nad-oxidized,nicotinamide-adenine dinucleotide,dpn-ox,beta-nicotinamide adenine dinucleotide,dpn+,nad,nad +
InChI Key BAWFJGJZGIEFAR-WIWLTUSXNA-N
Molecular Formula C21H27N7O14P2
2

b-Nicotinamide Adenine Dinucleotide, 95%, Spectrum™ Chemical
SDP

CAS: 53-84-9 Molecular Formula: C21H27N7O14P2 Molecular Weight (g/mol): 663.43 MDL Number: MFCD00150377 InChI Key: BAWFJGJZGIEFAR-WIWLTUSXNA-N IUPAC Name: 1-[(2R,3R,4S,5R)-5-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ⁵-pyridin-1-ylium SMILES: NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O

CAS 53-84-9
Molecular Weight (g/mol) 663.43
MDL Number MFCD00150377
SMILES NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
IUPAC Name 1-[(2R,3R,4S,5R)-5-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ⁵-pyridin-1-ylium
InChI Key BAWFJGJZGIEFAR-WIWLTUSXNA-N
Molecular Formula C21H27N7O14P2
3

Research Products International Corp NAD [B-NAD] [B-Nicotinamide Adenine Dinucleotide, Oxidized free acid hydrate], 1 Gram
SDP

β-Nicotinamide-Adenine Dinucleotide, Oxidized Form (β-NAD) is suitable for Enzyme synthesis / Biocatalysis applications. It is also applicable for making Enzyme Multiplied Immunoassay Technique (EMIT), Therapeutic Drug monitoring (TDM) and Blood Glucose reagents.

ENCOMPASS_PREFERRED
4

Research Products International Corp NAD 25 G
SDP

β-Nicotinamide-Adenine Dinucleotide, Oxidized Form (β-NAD) is suitable for Enzyme synthesis / Biocatalysis applications. It is also applicable for making Enzyme Multiplied Immunoassay Technique (EMIT), Therapeutic Drug monitoring (TDM) and Blood Glucose reagents.

ENCOMPASS_PREFERRED
5

Research Products International Corp NAD [B-NAD] [B-Nicotinamide Adenine Dinucleotide, Oxidized free acid hydrate], 5 Grams
SDP

β-Nicotinamide-Adenine Dinucleotide, Oxidized Form (β-NAD) is suitable for Enzyme synthesis / Biocatalysis applications. It is also applicable for making Enzyme Multiplied Immunoassay Technique (EMIT), Therapeutic Drug monitoring (TDM) and Blood Glucose reagents.

ENCOMPASS_PREFERRED
6

Medchemexpress LLC HY-F0002 100mg Medchemexpress, NADP (sodium salt) CAS:1184-16-3 Purity:>98%
SDP

Medchemexpress, HY-F0002 100mg NADP (sodium salt) CAS:1184-16-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

ENCOMPASS_PREFERRED
7

Medchemexpress LLC HY-101407 100mg Medchemexpress, Nicotinamide N-oxide CAS:1986-81-8 Purity:>98%
SDP

Medchemexpress, HY-101407 100mg Nicotinamide N-oxide CAS:1986-81-8 Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

ENCOMPASS_PREFERRED
8

Medchemexpress LLC Nicotinamide-guanine dinucleotide sodium | 2600354-60-5 | 701.41 | C21H26N7NaO15P2 | 10 MG
SDP

Nicotinamide-guanine dinucleotide sodium is a sodium salt analog of nicotinamide-guanine dinucleotide (an NAD analog) supplied as a research reagent. It functions as a coenzyme for alcohol dehydrogenase (ADH) in vitro and is provided in small laboratory pack sizes.

  • Functions as a coenzyme for alcohol dehydrogenase in vitro.
  • Sodium salt form suitable for biochemical assays.
  • Molecular weight 701.41 and formula C21H26N7NaO15P2.
  • Provided in a 10 mg research pack for laboratory use.
  • Intended for research applications and enzymatic studies.

ENCOMPASS_PREFERRED
9

Medchemexpress LLC Nicotinic acid mononucleotide | 321-02-8 | MFCD00070358 | 98.1% | 335.2 g·mol⁻1 | C11H14NO9P | 5 MG
SDP

Nicotinic acid mononucleotide (NaMN) is a nucleotide intermediate in the biosynthesis of NAD+. It is produced from nicotinic acid via phosphoribosyltransferase and serves as a substrate for adenylyltransferases involved in NAD+ metabolism. Supplied as a research-grade reagent for biochemical and enzymatic studies.

  • Intermediate in NAD+ biosynthesis and metabolism.
  • Substrate for adenylyltransferase and enzymatic assays.
  • High purity, typically ~98%.
  • Molecular weight 335.2 g·mol⁻1; formula C11H14NO9P.
  • Intended for research use only; not for human consumption.

ENCOMPASS_PREFERRED
10

Medchemexpress LLC HY-123033A 100mg Medchemexpress, Nicotinamide riboside (chloride) CAS:23111-00-4 Purity:>98%
SDP

Medchemexpress, HY-123033A 100mg Nicotinamide riboside (chloride) CAS:23111-00-4 Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride increases NAD [+] levels and activates SIRT1 and SIRT3 , culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

ENCOMPASS_PREFERRED
11

Medchemexpress LLC AICA-riboside, 5′-phosphate | 3031-94-5 | 100.0% | 338.21 g·mol⁻¹ | C9H15N4O8P | 5 MG
SDP

AICA-riboside, 5′-phosphate is the 5′-phosphorylated form of AICA-riboside that acts as an AMP mimetic and modulates adenosine uptake. It is used as a research reagent to activate AMP-activated protein kinase (AMPK) and to investigate cellular energy metabolism, metabolic disease models, and neuroprotective mechanisms.

  • Activates AMP-activated protein kinase via AMP mimetic activity.
  • Modulates adenosine uptake and extracellular adenosine concentration.
  • Used in studies of metabolic and neurological disorders.
  • Provided as a solid with manufacturer-stated high purity.
  • Available in small pack sizes suitable for laboratory research.

ENCOMPASS_PREFERRED
12

Medchemexpress LLC Nicotinamide riboside malate | 2415659-01-5 | MFCD34549739 | 98.0% | 388.33 g/mol | C15H20N2O10 | 1G
SDP

Nicotinamide riboside malate is the malate salt form of nicotinamide riboside, a bioavailable precursor of nicotinamide adenine dinucleotide (NAD+) used in research to elevate intracellular NAD+ levels and probe sirtuin-mediated pathways. It is commonly employed in studies of metabolism, aging, and mitochondrial function and is provided as a solid reagent for laboratory research (CAS 2415659-01-5).

  • Orally bioavailable NAD+ precursor.
  • Supports increased intracellular NAD+ levels.
  • Enables sirtuin activation and metabolic pathway studies.
  • Suitable for research on aging and mitochondrial function.
  • Supplied as a solid powder for laboratory use.

ENCOMPASS_PREFERRED
13

Medchemexpress LLC Nicotinamide riboside chloride | 23111-00-4 | MFCD27952781 | 99.6% | 290.70 | C11H15ClN2O5 | 5G
SDP

Nicotinamide riboside chloride is a riboside form of nicotinamide used as a research reagent and an NAD+ precursor for biochemical and metabolic studies. It is supplied as a white to light yellow solid and is intended for laboratory research use only.

  • Used as an NAD+ precursor in metabolic and aging research.
  • White to light yellow solid physical appearance.
  • Purity determined by LCMS: 99.6%.
  • Molecular formula: C11H15ClN2O5; molecular weight: 290.70 g/mol.
  • Recommended storage: 4°C, sealed, away from moisture and light; in solvent: -80°C (6 months) or -20°C (1 month).
  • Purity assay method: LCMS.

ENCOMPASS_PREFERRED
14

Medchemexpress LLC Nicotinamide riboside chloride | 23111-00-4 | MFCD27952781 | 99.9% | 290.70 g/mol | C11H15ClN2O5 | 25MG
SDP

Nicotinamide riboside chloride is an NAD+ precursor used as a research reagent to increase intracellular NAD+ levels and activate sirtuin enzymes (SIRT1, SIRT3). It is used in metabolic, mitochondrial, and neurodegenerative disease studies to probe NAD+ metabolism, oxidative metabolism, and neuroprotection.

  • High purity suitable for research applications (99.9%).
  • Orally active NAD+ precursor that elevates intracellular NAD+ and modulates sirtuin activity.
  • Commonly used to study oxidative metabolism, mitochondrial function, and neuroprotection.
  • Chemical formula C11H15ClN2O5; molecular weight 290.70 g/mol.
  • White to light-yellow solid, readily soluble in DMSO.
  • Available in small research packs (e.g., 25 mg).

ENCOMPASS_PREFERRED
15

Medchemexpress LLC Adenosine, N-(2-furanylmethyl)- | 4338-47-0 | MFCD00037987 | 99.9% | 347.33 g/mol | C15H17N5O5 | 50 MG
SDP

Kinetin riboside (Adenosine, N-(2-furanylmethyl)-) is a ribosylated cytokinin analog used in biochemical and cell biology research. It induces apoptosis in cancer cells and inhibits proliferation of HCT-15 cells (IC50 = 2.5 μM). The reagent is supplied as a high-purity solid and is intended for cell-based assays investigating apoptosis, proliferation, and cytotoxicity.

  • High purity: 99.88%.
  • Molecular weight: 347.33 g/mol.
  • Chemical formula: C15H17N5O5.
  • Appearance: solid, white to off-white.
  • Storage: powder -20°C for long term; in solvent -80°C recommended.
  • Reported bioactivity: induces apoptosis and inhibits HCT-15 cell proliferation (IC50 2.5 μM).
  • Pack sizes suitable for small-scale research, including 50 mg.

ENCOMPASS_PREFERRED