Drug Standards
Medchemexpress LLC Doxycycline (monohydrate) | 17086-28-1 | 99.0% | 462.45 | 1 ML
Doxycycline monohydrate is an antibiotic and a broad-spectrum metalloproteinase (MMP) inhibitor. It is intended for research use only.
- Reduces expression of mitochondrial encoded cytochrome c oxidase I (MT-CO1) protein and increases glucose consumption.
- Protects cells from hypoxia-induced glioma cell death at low concentrations.
- Reduces MMP-9 activity and collagen degradation.
- Prevents vascular lesions in heterozygous Col3a1 knockout mouse models.
- Used as an inducer to control gene expression in Tet-On/Tet-Off systems.
- Associated with clinical trials for various conditions.
Medchemexpress LLC Clopidogrel-related Compound B (hydrochloride) | 144750-52-7 | 99.7% | 358.28 | 50 MG
Clopidogrel-related Compound B hydrochloride is an impurity of Clopidogrel. It is a solid with a white to yellow appearance, typically used for laboratory research.
- High purity at 99.67%
- Molecular weight of 358.28
- Chemical formula is C16H17Cl2NO2S
- Identified by CAS number 144750-52-7
Medchemexpress LLC Amodiaquine impurity 1 | 81099-86-7 | 98.7% | 270.72 | 1 G
Amodiaquine impurity 1 is a chemical compound with the molecular formula C15H11ClN2O, appearing as a light yellow to yellow solid. It is intended for use as a laboratory chemical and in the manufacture of substances.
- High purity of 98.70% by HPLC
- Molecular formula: C15H11ClN2O
- Appearance: light yellow to yellow solid
- Stable under recommended storage conditions
- Requires protection from light and storage under nitrogen
Medchemexpress LLC Naphazoline hydrochloride | 550-99-2 | 99.4% | 5 G
Naphazoline hydrochloride is a potent α-adrenergic receptor agonist. It reduces vascular hyperpermeability and promotes vasoconstriction. This compound also decreases the levels of inflammatory factors (TNF-α, IL-1β, IL-6), cytokines (IFN-γ, IL-4), IgE, GMCSF, and NGF. It is used in research for non-bacterial conjunctivitis.
- Reduces vascular hyperpermeability
- Promotes vasoconstriction
- Decreases inflammatory factors (TNF-α, IL-1β, IL-6)
- Decreases cytokines (IFN-γ, IL-4)
- Decreases IgE, GMCSF, and NGF levels
- Used in research for non-bacterial conjunctivitis
Medchemexpress LLC Triamcinolone | 124-94-7 | 99.8% | 5 G
Triamcinolone is a long-acting corticosteroid that exhibits anti-inflammatory, anti-oedematous, anti-proliferative, anti-angiogenetic, immunomodulatory, and neuroprotective effects by binding to glucocorticoid receptors. It is used to alleviate several dermatitis, immune diseases, and ocular diseases.
- Long-acting corticosteroid.
- Exhibits anti-inflammatory, anti-oedematous, anti-proliferative, anti-angiogenetic, immunomodulatory, and neuroprotective effects.
- Binds to glucocorticoid receptors.
- Used to alleviate dermatitis, immune diseases, and ocular diseases.
- Demonstrates dose-dependent inhibition of bovine retinal endothelial cell proliferation.
- Lowers neovascular cell count in retinopathy of prematurity animal models.
- Investigated in numerous clinical trials.
Medchemexpress LLC Niclosamide (olamine) | 1420-04-8 | 98.7% | 100 MG
Niclosamide olamine is an orally active antihelminthic agent used in parasitic infection research. It acts as a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells. This compound also exhibits biological activities against cancer and suppresses DNA replication in Vero E6 cells.
- Orally active antihelminthic agent
- Used in parasitic infection research
- STAT3 inhibitor
- Exhibits biological activities against cancer
- Inhibits DNA replication in Vero E6 cells
- Inhibits adrenocortical carcinoma cellular proliferation
- Inhibits STAT3-mediated luciferase reporter activity
- Inhibits virus replication in Vero E6 cells
Medchemexpress LLC Alverine citrate | 5560-59-8 | 99.5% | 10 MM 1 ML
Alverine citrate is a 5-HT1A receptor antagonist with an IC50 of 101 nM, primarily used for research and analytical applications. It acts directly on gut muscles, causing relaxation, and is used in studies of functional gastrointestinal disorders. This compound shows high affinity for 5-HT1A receptors and weak affinity for 5-HT3 and 5-HT4 subtypes.
- 5-HT1A receptor antagonist
- IC50 of 101 nM
- Used for research and analytical applications
- Relaxes gut muscles
- High affinity for 5-HT1A receptors
- Molecular formula: C26H35NO7
- Molecular weight: 473.56
- Appearance: White to off-white solid
Medchemexpress LLC Flunixin meglumine | 42461-84-7 | 99.5% | 100 MG
Flunixin meglumine (Standard) is an analytical standard and a cyclooxygenase (COX) inhibitor. It demonstrates anti-inflammatory effects, making it suitable for various research and analytical applications.
- Analytical standard for research
- Acts as a cyclooxygenase (COX) inhibitor
- Exhibits anti-inflammatory effects
- Used as a reference standard in HPLC, GC, and MS experiments
Medchemexpress LLC 3-(4-bromo-7-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione | 2438239-34-8 | ≥97.0% | 341.13 g/mol | C13H10BrFN2O3 | 50 MG
Lenalidomide-4-Br-7-fluoro is a synthetic analog of lenalidomide bearing bromine and fluorine substituents on the benzyl ring. Supplied as a solid research-use compound, it is used in chemical biology and medicinal chemistry to probe cereblon engagement and structure-activity relationships. The material is offered at high purity for analytical and biological studies.
- Derivative of lenalidomide with bromo and fluoro substituents.
- Used to study cereblon (CRBN) ligand interactions and degradation pathways.
- Provided as a solid powder suitable for small-scale assays and synthesis.
- High purity appropriate for analytical and biological experiments.
- Available in small pack sizes for research screening workflows.
Medchemexpress LLC Diclofenac ethyl ester | 15307-77-4 | 99.3% | 100 MG
Diclofenac ethyl ester is a prodrug of Diclofenac, designed for enhanced delivery. It is encapsulated in polymer micelles in vitro and released with prolonged circulation time and reduced drug concentrations in the heart and kidneys in vivo.
- Prodrug of Diclofenac
- Encapsulated in polymer micelles
- Prolonged circulation time
- Reduced drug concentrations in heart and kidneys
Medchemexpress LLC Fostamatinib | 901119-35-5 | 99.7% | 1 MG
Fostamatinib (R788) is an oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. This compound also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).
- Oral proagent of the active compound R406
- Orally available and competitive Syk/FLT3 inhibitor
- Inhibits Lyn and Lck
Medchemexpress LLC Cabozantinib | 849217-68-1 | >98% | 500 MG
Cabozantinib is a potent and orally active inhibitor of VEGFR2 and MET. It displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3. Cabozantinib shows antiangiogenic activity, disrupts tumor vasculature, and promotes tumor and endothelial cell apoptosis.
- Potent and orally active inhibitor of VEGFR2 and MET
- Displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3
- Shows antiangiogenic activity
- Disrupts tumor vasculature
- Promotes tumor and endothelial cell apoptosis
Medchemexpress LLC CPD-10 | 3055471-57-0 | 96.7% | 888.07 | 1 MG
CPD-10 is a potent CCND1 and CDK4 PROTAC degrader. It shows anti-proliferation and induces apoptosis. CPD-10 decreases the protein expression of cyclin D1, cyclin D3, CDK4, and P-Rb(5807/811) in a dose-dependent manner.
- Potent CCND1 and CDK4 PROTAC degrader
- Shows anti-proliferation
- Induces apoptosis
- Decreases protein expression of cyclin D1, cyclin D3, CDK4, P-Rb(5807/811) in a dose-dependent manner
Medchemexpress LLC Ibiglustat succinate | 1629063-80-4 | 99.7% | 507.57 | 2 MG
Ibiglustat succinate is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. It is used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.
- Orally active
- Brain-penetrant glucosylceramide synthase (GCS) inhibitor
- Can prevent additional GL-3 accumulation in Fabry disease cells
Medchemexpress LLC Cpd-10 | 3055471-57-0 | 96.7% | 888.07 | 50 MG
CPD-10 is a potent CCND1 and CDK4 PROTAC degrader that exhibits anti-proliferation effects and induces apoptosis. It decreases the protein expression of cyclin D1, cyclin D3, CDK4, and P-Rb(5807/811) in a dose-dependent manner. This compound is composed of a CDK ligand, an E3 Ligase Ligand-Linker Conjugates ligand, and a linker.
- Potent CCND1 and CDK4 PROTAC degrader
- Shows anti-proliferation
- Induces apoptosis
- Decreases protein expression of cyclin D1, cyclin D3, CDK4, P-Rb(5807/811) in a dose-dependent manner