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Filtered Search Results
Selleck Chemical LLC Lenalidomide S1029-500mg
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Lenalidomide is a TNF- secretion inhibitor with IC50 of 13 nM in PBMCs Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) and it causes selective ubiquitination and degradation of two lymphoid transcription factors IKZF1 and IKZF3 by the CRBN-CRL4 ubiquitin ligase Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis
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Apexbio Technology LLC Glipizide 29094-61-9 500mg
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Glipizide (CAS 29094-61-9) is a small molecule that acts by inhibiting ATP-sensitive potassium channels in pancreatic cells leading to membrane depolarization and subsequent stimulation of insulin secretion Additionally it modulates ATP-dependent K channels in GABAergic neurons within the brain Glipizide is widely used in research to investigate pancreatic cell physiology insulin release mechanisms and the role of KATP channels in neuroendocrine regulation
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Sigma Aldrich Fine Chemicals Biosciences Digoxigenin European Pharmacopoeia (EP) Reference Standard | 1672-46-4 | MFCD00871861 |
Digoxigenin European Pharmacopoeia (EP) Reference Standard | Mol Wt: 390.51 | 1672-46-4 | MFCD00871861 |
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Medchemexpress LLC (1R)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol | 1212376-05-0 | MFCD09863591 | 500mg
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Ticagrelor impurity 89 is an impurity of Ticagrelor (HY-10064)
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000772043 MELOXICAM IMPURITY 5 1G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000772407 TELMISARTAN IMPURITY 100G
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Selleck Chemical LLC Pantoprazole S2105-500mg
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Pantoprazole (SKF96022 BY-1023) is a proton pump inhibitor drug that inhibits gastric acid secretion It works on gastric parietal cells to irreversibly inhibit (H /K )-ATPase function and suppress the production of gastric acid
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Medchemexpress LLC Tenofovir Disoproxil fumarate | 202138-50-9 | 99.65% | 635.51 | 200 MG
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Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B. It is intended for research use only and not for patient administration. The product is available as a solid, appearing as a white to off-white substance.
- Exhibited an IC50 of 4.7 μM against HIV-1 in HeLa cells.
- Showed an IC50 of 5.1 μM against Hepatitis B virus in HepG2 cells.
- Demonstrated dose-dependent activity during vaginal HIV challenge in BLT mice.
- Indicated safety and effectiveness in an HBV infection model in woodchucks.
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Apexbio Technology LLC Nocodazole 31430-18-9 50mg
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Nocodazole (CAS 31430-18-9) is an anti-mitotic small molecule commonly utilized in biomedical research as a potent and reversible inhibitor of microtubule polymerization Its mechanism involves direct binding to -tubulin disrupting microtubule assembly and stability It exhibits inhibitory effects on various kinases associated with oncogenesis including Abl c-Kit BRAF and MEK and induces apoptosis in cancer cells In vitro exposure at high concentrations rapidly depolymerizes microtubules while lower concentrations primarily affect their dynamic instability Nocodazole serves as a valuable tool in studies probing microtubule dynamics intracellular trafficking cell cycle regulation and antitumor therapeutic evaluations
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669762 ESCULIN STANDARD 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669842 APIXABAN IMPURITY 46 250MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669848 APIXABAN IMPURITY 50 500MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669856 CANAGLIFLOZIN IMPURI 10MG
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000568039 PRUCALOPRIDE-SUCCINAT-200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000692408 PHENYTOIN STANDARD 50MG
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