Acetylides

eMolecules​ 17880-61-4 | METHYL 5-ETHYNYLPYRIDINE-2-CARBOXYLATE | AstaTech | MFCD13189756 | 161.160 | C9H7NO2 | 95.000 | COC(=O)c1ccc(cn1)C#C | 1g | 222802523

METHYL 5-ETHYNYLPYRIDINE-2-CARBOXYLATE | AstaTech | 17880-61-4 | MFCD13189756 | 161.160 | C9H7NO2 | 95.000 | COC(=O)c1ccc(cn1)C#C | 1g | 222802523

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Medchemexpress LLC Propargyl-PEG6-acid | 1951438-84-8 | 348.39 g·mol⁻1 | C16H28O8 | 100 MG

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Propargyl-PEG6-acid is a PEG-based linker bearing a terminal propargyl (alkyne) group, used as a click-chemistry reagent and as a linker in the synthesis of PROTACs and antibody-drug conjugates. The PEG6 spacer increases hydrophilicity and enables conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC).

• Contains a terminal propargyl (alkyne) functional group.
• Suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Used in synthesis of PROTACs and antibody-drug conjugates.
• PEG6 spacer provides hydrophilicity and improved solubility.
• Storage recommendations: pure form refrigerated or frozen for long-term stability; store solutions frozen.

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eMolecules​ 1072951-56-4 | (5-Bromo-2-(trifluoromethoxy)phenyl)boronic acid | MFCD11504857 | 1g

ChemScene | 2-Fluoro-4-hydroxybenzamide | 250mg | 632274220 | CS-0149671 | 1133122-96-9 | MFCD09999525 | 155.128 | C7H6FNO2

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eMolecules​ 1256345-87-5 | 3-Ethoxy-5-(trifluoromethoxy)phenylboronic acid | Combi-Blocks | MFCD16295059 | 249.980 | C9H10BF3O4 | 97.000 | CCOc1cc(OC(F)(F)F)cc(c1)B(O)O | 1g | 117524556

3-Ethoxy-5-(trifluoromethoxy)phenylboronic acid | Combi-Blocks | 1256345-87-5 | MFCD16295059 | 249.980 | C9H10BF3O4 | 97.000 | CCOc1cc(OC(F)(F)F)cc(c1)B(O)O | 1g | 117524556

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Medchemexpress LLC Propargyl-PEG5-Br | 1287660-83-6 | 339.22 | 1 G

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Propargyl-PEG5-Br is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs and functions as a click chemistry reagent. It contains an Alkyne group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Enables synthesis of PROTACs
• Functions as a click chemistry reagent
• Features an alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules
• Supports development of PROTACs for target protein degradation

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Medchemexpress LLC Propargyl-PEG10-acid | 2055022-18-7 | 98.0% | 524.60 | 500 MG

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Propargyl-PEG10-acid is a PEG derivative that features a propargyl group along with a terminal carboxylic acid. It functions as a click chemistry reagent, containing an Alkyne group, and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules that possess Azide groups.

• PEG derivative
• Features a propargyl group
• Contains a terminal carboxylic acid
• Functions as a click chemistry reagent
• Contains an alkyne group
• Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
• Suitable for PROTAC synthesis
• Used as a biochemical assay reagent

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Medchemexpress LLC Propargyl-PEG3-amine | 932741-19-0 | 98.0% | 187.24 | 100 MG

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Propargyl-PEG3-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent that contains an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Click chemistry reagent
• Contains an alkyne group
• Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups

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eMolecules​ 4-Fluoro-2-(trifluoromethoxy)-DL-phenylalanine | 1435806-18-0 | MFCD19687192 | 1g

Apollo Scientific | 4-Fluoro-2-(trifluoromethoxy)-DL-phenylalanine | 1g | 562460231 | PC302877 | | 1435806-18-0 | MFCD19687192 | 267.180 | C10H9F4NO3

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Medchemexpress LLC Propargyl-PEG6-alcohol | 944560-99-0 | 97.0% | 1 G

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Propargyl-PEG6-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Used in the synthesis of proteolysis targeting chimeras (PROTACs)
• Contains an alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc)
• PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

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Medchemexpress LLC Propargyl-PEG8-NH2 | 1196732-52-1 | MFCD28334507 | >98.0% | 407.50 g/mol | C19H37NO8 | 10 MG

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Propargyl-PEG8-NH2 is an alkyne-terminated polyethylene glycol (PEG8) amine linker used for bioconjugation and linker synthesis. It provides a terminal alkyne for click chemistry and a primary amine for further derivatization, with a PEG8 spacer to improve solubility and spacing between conjugated moieties.

• Provides a terminal alkyne group for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
• Contains a primary amine for amide formation and further functionalization.
• PEG8 spacer improves solubility and reduces steric hindrance.
• High chemical purity suitable for research applications.
• Colorless to light yellow liquid, convenient for solution-phase coupling reactions.
• Commonly used in PROTAC, ADC, and general bioconjugation workflows.

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Medchemexpress LLC Ethanamine, 2-[2-(2-propyn-1-yloxy)ethoxy]- | 944561-44-8 | MFCD19160595 | 99.6% | 143.18 g/mol | C7H13NO2 | 100 G

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Propargyl-PEG2-amine is a PEG-based bifunctional linker that contains a terminal propargyl (alkyne) group and a primary amine, designed for conjugation chemistry and synthetic applications such as antibody-drug conjugate (ADC) formation, PROTAC assembly, and click chemistry.

• PEG-2 spacer with terminal propargyl group
• Primary amine functional group for conjugation
• High purity suitable for synthesis (99.6%)
• Colorless to light yellow liquid; density 0.992 ± 0.06 g/cm3
• Compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC)

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Medchemexpress LLC Propargyl-PEG3-bromide | 203740-63-0 | 97.7% | 251.12 | 500 MG

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Propargyl-PEG3-bromide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Click chemistry reagent
• Contains an alkyne group
• Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups

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Medchemexpress LLC Propargyl-PEG6-acid | 1951438-84-8 | ≥97.0% | 348.39 g/mol | C16H28O8 | 250 MG

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Propargyl-PEG6-acid is a PEG-based linker and click chemistry reagent containing a terminal alkyne. It is used as a linker in PROTAC and ADC synthesis and for copper-catalyzed azide-alkyne cycloaddition (CuAAc) bioconjugation reactions.

• cleavable PEG6 linker suitable for PROTAC and ADC synthesis
• contains a terminal propargyl (alkyne) group for click chemistry
• high purity (≥97.0% by NMR) suitable for research applications
• molecular weight 348.39 g/mol, molecular formula C16H28O8
• storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month)

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eMolecules​ 1706428-65-0 | 2-Methyl-4-(trifluoromethoxy)-DL-phenylalanine | Apollo Scientific | MFCD22201062 | 263.216 | C11H12F3NO3 | 95.000 | Cc1cc(OC(F)(F)F)ccc1CC(N)C(O)=O | 1g | 562461290

2-Methyl-4-(trifluoromethoxy)-DL-phenylalanine | Apollo Scientific | 1706428-65-0 | MFCD22201062 | 263.216 | C11H12F3NO3 | 95.000 | Cc1cc(OC(F)(F)F)ccc1CC(N)C(O)=O | 1g | 562461290

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Chemscene ChemScene | 4-Chloro-2-(trifluoromethoxy)aniline | 10G | CS-W015037 | 0.98 | 175205-77-3| MFCD00153102 | 211.57

ChemScene | 4-Chloro-2-(trifluoromethoxy)aniline | 10G | CS-W015037 | 0.98 | 175205-77-3| MFCD00153102 | 211.57

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