Acetylides
eMolecules 96439-99-5 | 3-Bromo-2-ethynylpyridine | MFCD18256373 | 1g
Ambeed | 3-Bromo-2-ethynylpyridine | 1g | 600847246 | A758874 | 96439-99-5 | MFCD18256373 | 182.020 | C7H4BrN
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Medchemexpress LLC Propargyl-PEG1-bromide | 18668-74-1 | MFCD00099299 | 99.2% | 163.01 g/mol | C5H7BrO | 5 G
Propargyl-PEG1-bromide is a small polyethylene glycol (PEG) derivative bearing a terminal propargyl (alkyne) group and a bromide leaving group. It is designed for use as a reactive linker or alkylating reagent in bioconjugation, click chemistry, and drug-delivery research. Supplied as a liquid, it provides a short PEG spacer with an alkyne handle for efficient coupling reactions.
- Provides terminal alkyne for copper-catalyzed azide-alkyne cycloaddition.
- Contains a bromide leaving group for nucleophilic substitution reactions.
- Short PEG spacer improves aqueous solubility and reduces steric hindrance.
- Suitable for conjugation and linker synthesis in medicinal chemistry workflows.
- Compatible with standard storage recommendations when handled under inert atmosphere.
Medchemexpress LLC Arecaidine propargyl ester hydrobromide | 116511-28-5 | MFCD00078566 | 99.5% | 260.13 g/mol | C10H14BrNO2 | 5 MG
Arecaidine propargyl ester hydrobromide is a research-grade small molecule that acts as an agonist of M2 muscarinic acetylcholine receptors and has been reported to induce apoptosis, increase reactive oxygen species, and cause G2/M cell-cycle arrest in certain tumor cell models.
- Purity: 99.5%.
- Appearance: white to off-white solid.
- Molecular weight: 260.13 g/mol.
- Chemical formula: C10H14BrNO2.
- Biological activity: M2 muscarinic receptor agonist; reported inhibition of tumor cell proliferation.
- Storage: store sealed at 4°C; in solvent, -80°C up to 6 months or -20°C up to 1 month.
- Pack sizes: available in 1 mg, 5 mg, and 10 mg.
eMolecules 1256345-87-5 | 3-Ethoxy-5-(trifluoromethoxy)phenylboronic acid | Combi-Blocks | MFCD16295059 | 249.980 | C9H10BF3O4 | 97.000 | CCOc1cc(OC(F)(F)F)cc(c1)B(O)O | 1g | 117524556
3-Ethoxy-5-(trifluoromethoxy)phenylboronic acid | Combi-Blocks | 1256345-87-5 | MFCD16295059 | 249.980 | C9H10BF3O4 | 97.000 | CCOc1cc(OC(F)(F)F)cc(c1)B(O)O | 1g | 117524556
Medchemexpress LLC Propargyl-PEG10-acid | 2055022-18-7 | 98.0% | 524.60 | 500 MG
Propargyl-PEG10-acid is a PEG derivative that features a propargyl group along with a terminal carboxylic acid. It functions as a click chemistry reagent, containing an Alkyne group, and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules that possess Azide groups.
- PEG derivative
- Features a propargyl group
- Contains a terminal carboxylic acid
- Functions as a click chemistry reagent
- Contains an alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Suitable for PROTAC synthesis
- Used as a biochemical assay reagent
Medchemexpress LLC Propargyl-PEG3-amine | 932741-19-0 | 98.0% | 187.24 | 100 MG
Propargyl-PEG3-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent that contains an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups
Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 50 MG
Propargyl-PEG9-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules containing Azide groups
eMolecules 1706428-65-0 | 2-Methyl-4-(trifluoromethoxy)-DL-phenylalanine | Apollo Scientific | MFCD22201062 | 263.216 | C11H12F3NO3 | 95.000 | Cc1cc(OC(F)(F)F)ccc1CC(N)C(O)=O | 1g | 562461290
2-Methyl-4-(trifluoromethoxy)-DL-phenylalanine | Apollo Scientific | 1706428-65-0 | MFCD22201062 | 263.216 | C11H12F3NO3 | 95.000 | Cc1cc(OC(F)(F)F)ccc1CC(N)C(O)=O | 1g | 562461290
Medchemexpress LLC Bis-PEG1-C-PEG1-CH2COOH (PROTAC Linker 26) | 2358775-67-2 | 95.0% | 50 MG
Bis-PEG1-C-PEG1-CH2COOH, also known as PROTAC Linker 26, is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds designed to induce the degradation of target proteins by exploiting the intracellular ubiquitin-proteasome system, and they consist of two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein. This product is intended for research use only.
- PEG-based PROTAC linker: can be used in the synthesis of PROTACs.
- Key component for PROTACs: PROTACs contain two different ligands connected by a linker, targeting an E3 ubiquitin ligase and the protein of interest.
- Induces protein degradation: PROTACs utilize the ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) | 2112732-01-9 | 519.58 | 25 MG
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTACs and acts as a click chemistry reagent. This linker contains an alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that possess azide groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
Medchemexpress LLC Propargyl-PEG3-acid | 1347760-82-0 | 99.1% | 216.23 | C10H16O5 | 250 MG
Propargyl-PEG3-acid is a PEG-based bifunctional linker featuring a terminal propargyl (alkyne) group and a carboxylic acid; it is used as a non-cleavable three-unit PEG linker for antibody-drug conjugates and as a PEG linker for PROTACs, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
- Non-cleavable three-unit PEG linker suitable for ADC and PROTAC synthesis.
- Terminal alkyne enables copper-catalyzed azide-alkyne cycloaddition for conjugation to azide-containing molecules.
- High purity appropriate for research-scale bioconjugation workflows.
- Available in multiple pack sizes to support small-scale and larger preparative work.
Medchemexpress LLC Propargyl-PEG8-acid | 2055014-94-1 | 98.0% | 436.49 g/mol | C20H36O10 | 1 G
Propargyl-PEG8-acid is a polyethylene glycol (PEG) based linker bearing a terminal propargyl (alkyne) group and a carboxylic acid, used for conjugation in PROTAC and antibody-drug conjugate (ADC) synthesis.
- Contains a terminal propargyl alkyne for click chemistry.
- Provides a carboxylic acid handle for amide coupling.
- Approximate molecular weight 436.49 g/mol.
- High purity (98.0%) suitable for research applications.
- Available in multiple pack sizes, including 1 G for lab-scale use.
Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 250 MG
Propargyl-PEG9-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent that contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Click chemistry reagent
- Alkyne group for reactions
- Used in PROTAC synthesis
- Applicable in cancer research
- Supports cancer targeted therapy
- PROTAC linker
eMolecules 1206972-45-3 | 2-Chloro-5-(trifluoromethoxy)pyridine | MFCD18257007 | 1g
Ambeed | 2-((Tetrahydro-2H-pyran-4-yl)oxy)-5-(4455-tetramethyl-132-dioxaborolan-2-yl)benzonitrile | 100mg | 602852409 | A728926 | 1292317-54-4 | MFCD22393670 | 329.200 | C18H24BNO4
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Medchemexpress LLC Propargyl-PEG8-NHS ester | 2182601-74-5 | 95.0% | 533.57 g/mol | C24H39NO12 | 100 MG
Propargyl-PEG8-NHS ester is a PEG-based linker and click-chemistry reagent containing a propargyl (alkyne) group and an N-hydroxysuccinimide (NHS) ester for amine coupling. It is intended for bioconjugation workflows including PROTAC and antibody-drug conjugate linker synthesis.
- Contains an alkyne (propargyl) group for copper-catalyzed azide-alkyne cycloaddition.
- Features an NHS ester for efficient coupling to primary amines.
- Molecular weight 533.57 g/mol and formula C24H39NO12.
- Typical purity 95.0%.
- Available in small research quantities (e.g., 100 MG) for bioconjugation studies.
- Recommended storage: pure form at -20°C to preserve stability.