Acetylides
Medchemexpress LLC Propargyl-PEG8-NH2 | 1196732-52-1 | 98.0% | 10 G
Propargyl-PEG8-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound is a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Peg-based protac linker
- Non-cleavable adc linker
- Click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Medchemexpress LLC Propargyl-PEG2-OH | 7218-43-1 | 99.7% | 25 G
Propargyl-PEG2-OH is a versatile PEG-based PROTAC linker. This compound is instrumental in the synthesis of Thalidomide-O-PEG2-propargyl and serves as a key reagent in click chemistry. Its unique Alkyne group facilitates efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups, enabling broad applications in chemical synthesis and biochemical research.
- Functions as a PEG-based PROTAC linker
- Utilized in the synthesis of Thalidomide-O-PEG2-propargyl
- Acts as a click chemistry reagent
- Contains an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules
Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 100 MG
Propargyl-PEG9-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that possess Azide groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an alkyne group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules possessing azide groups
Medchemexpress LLC Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 1,1-dimethylethyl ester | 1807503-80-5 | 95.0% | 1 G
Propargyl-PEG2-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Functions as a PEG-based PROTAC linker
- Used for synthesizing PROTACs
- Acts as a click chemistry reagent
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules
Medchemexpress LLC Propargyl-PEG6-NH2 | 1198080-04-4 | 99.7% | 250 MG
Propargyl-PEG6-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Alkyne group for CuAAc reactions
- Exploits the intracellular ubiquitin-proteasome system to degrade target proteins
eMolecules 331-26-0 | 2-Chloro-5-(trifluoromethoxy)aniline | MFCD16658882 | 1g
ChemScene | DPEPO | 5g | 536795585 | CS-0062614 | 808142-23-6 | MFCD28968111 | 570.565 | C36H28O3P2
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Medchemexpress LLC Propargyl-O-C1-amido-PEG4-C2-NHS ester | 2101206-92-0 | 95.0% | 458.46 | C20H30N2O10 | 25 MG
Propargyl-O-C1-amido-PEG4-C2-NHS ester is a non-cleavable PEG4-based NHS ester linker with a terminal propargyl (alkyne) group used for copper-catalyzed azide-alkyne cycloaddition (CuAAC) bioconjugation and antibody-drug conjugate synthesis.
- Non-cleavable PEG4 NHS ester linker.
- Terminal alkyne (propargyl) for CuAAC click chemistry.
- Suitable for antibody-drug conjugate synthesis and general bioconjugation.
- Molecular weight 458.46; formula C20H30N2O10; CAS 2101206-92-0.
- Purity 95.0%.
Medchemexpress LLC Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-(4-methylbenzenesulfonate) | 1119249-30-7 | 98.2% | 250 MG
Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker used in the synthesis of Thalidomide-O-PEG2-propargyl. It functions as a click chemistry reagent, incorporating an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an alkyne group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Can be used to synthesize Thalidomide-O-PEG2-propargyl
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Propargyl-PEG3-methane | 89635-82-5 | MFCD27977518 | 98.0% | 202.25 | 500 MG
Propargyl-PEG3-methane is a PEG-based PROTAC linker, designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). It functions as a versatile click chemistry reagent, facilitating various bioconjugation and labeling applications.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Facilitates bioconjugation and labeling
Medchemexpress LLC Propargyl-PEG8-NHS ester | 2182601-74-5 | 97.0% | 1 G
Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker primarily used in the synthesis of PROTACs and as a cleavable ADC linker in the synthesis of antibody-drug conjugates (ADCs). It functions as a click chemistry reagent due to its alkyne group.
- Contains an alkyne group for chemical reactions
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules
- Suitable for PROTAC synthesis
- Ideal for antibody-drug conjugate (ADC) synthesis
Medchemexpress LLC Propargyl-PEG4-Boc | 1355197-66-8 | 316.39 | 250 MG
Propargyl-PEG4-Boc is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that readily undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. This reagent facilitates the creation of PROTACs, which are compounds that exploit the ubiquitin-proteasome system to degrade target proteins.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Alkyne group for CuAAc reactions
- Used in the synthesis of PROTACs
Accela Chembio Inc MF: C7H5N | MW: 103.12 | >97% | Flash Point: 76 celsius | BP: 90¿C/30mmHg | Density: 1.0190.
MF: C7H5N | MW: 103.12 | >97% | Flash Point: 76 celsius | BP: 90¿C/30mmHg | Density: 1.0190.
Medchemexpress LLC Bis-PEG1-C-PEG1-CH2COOH | 2358775-67-2 | 95.0% | 10 MG
Bis-PEG1-C-PEG1-CH2COOH (PROTAC Linker 26) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based protac linker
- Used in the synthesis of protacs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 2-Bromo-5-(trifluoromethoxy)phenylisocyanate | | | 25g
Apollo Scientific | 2-Bromo-5-(trifluoromethoxy)phenylisocyanate | 25g | 562453349 | PC503000 | | | | 282.016 | C8H3BrF3NO2
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eMolecules 5-Chloro-2-(trifluoromethoxy)phenylboronic acid | 870822-78-9 | MFCD10697424 | 1g
Combi-Blocks | 5-Chloro-2-(trifluoromethoxy)phenylboronic acid | 1g | 117529394 | FA-1805 | 96.000 | 870822-78-9 | MFCD10697424 | 240.370 | C7H5BClF3O3
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