Acetylides
eMolecules 1036204-60-0 | Propargyl-PEG6-alcohol | Broadpharm | MFCD27635181 | 276.329 | C13H24O6 | 98.000 | OCCOCCOCCOCCOCCOCC#C | 1g | 229582392
Propargyl-PEG6-alcohol | Broadpharm | 1036204-60-0 | MFCD27635181 | 276.329 | C13H24O6 | 98.000 | OCCOCCOCCOCCOCCOCC#C | 1g | 229582392
Medchemexpress LLC Propargyl-PEG8-acid | 2055014-94-1 | 98.0% | 436.49 g/mol | C20H36O10 | 100 MG
Propargyl-PEG8-acid is a propargyl-functionalized polyethylene glycol (PEG8) carboxylic acid linker designed for bioconjugation and linker chemistry. It provides a PEG8 spacer with a terminal alkyne for click chemistry and a carboxylic acid for coupling reactions; it is supplied as a high-purity solid with defined stability and storage requirements.
- Propargyl terminal alkyne suitable for copper-catalyzed click chemistry.
- Peg8 spacer improves solubility and flexibility in conjugates.
- Carboxylic acid functionality enables amide coupling and derivatization.
- High purity (approximately 98.0%) for reliable synthetic performance.
- Molecular weight 436.49 g/mol, formula C20H36O10.
- Available in small-scale packs (100 mg) and larger sizes for scale-up.
- Store at -20°C under inert atmosphere; in solvent, follow recommended cold storage times.
Medchemexpress LLC Propargyl-PEG8-OH | 1351556-81-4 | 100 MG
Propargyl-PEG8-OH is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This click chemistry reagent contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
eMolecules 886500-85-2 | 4-Chloro-3-(trifluoromethoxy)phenol | Apollo Scientific | MFCD06660247 | 212.550 | C7H4ClF3O2 | 98.000 | Oc1ccc(Cl)c(OC(F)(F)F)c1 | 1g | 562453315
4-Chloro-3-(trifluoromethoxy)phenol | Apollo Scientific | 886500-85-2 | MFCD06660247 | 212.550 | C7H4ClF3O2 | 98.000 | Oc1ccc(Cl)c(OC(F)(F)F)c1 | 1g | 562453315
eMolecules 21020-27-9 | 4-METHYL-2-PENTYNE | AstaTech | MFCD00041615 | 82.146 | C6H10 | 95.000 | CC#CC(C)C | 0.25g | 718058629
4-METHYL-2-PENTYNE | AstaTech | 21020-27-9 | MFCD00041615 | 82.146 | C6H10 | 95.000 | CC#CC(C)C | 0.25g | 718058629
Matrix Scientific 4-ETHYNYLBENZOIC ACID4-ETHYN-1
4-ethynylbenzoic Acid Mf C9h6o2 Mw 146.15 Cas 10602-00-3 Mdl MFCD00168819
Medchemexpress LLC Propargyl-PEG4-acid | 1415800-32-6 | 97.0% | 10 G
Propargyl-PEG4-acid is a PEG-based PROTAC linker. It can be used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and analogue PROTAC 3, which causes BTK degradation. Propargyl-PEG4-acid is also a click chemistry reagent, featuring an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in synthesis of BTK-IAP PROTACs
- PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells
- Click chemistry reagent with Alkyne group
- Can undergo CuAAc with Azide groups
