Organic calcium salts
Medchemexpress LLC Pyruvate Carboxylase-IN-5 | 3047101-14-1 | 98.9% | 294.24 | 1 ML
Pyruvate Carboxylase-IN-5 (compound 6m) is a pyruvate carboxylase inhibitor with high selectivity and permeability. Pyruvate carboxylase is a mitochondrial enzyme that catalyzes the carboxylation of pyruvate to oxaloacetate, a process that plays an important role in maintaining steady-state levels of Krebs cycle intermediates, which are precursors for the synthesis of biomacromolecules such as amino acids, fatty acids, and glucose.
- Pyruvate carboxylase inhibitor
- High selectivity
- High permeability
- For research use only
Medchemexpress LLC Pyruvate decarboxylase | 9001-04-1 | ≥1 U/mg solid | 60 kDa | 20 U
Pyruvate decarboxylase (PDC) is an enzyme that catalyzes the decarboxylation of pyruvic acid to acetaldehyde. It specifically catalyzes the non-oxidative conversion of pyruvate (or other 2-oxo acids) to acetaldehyde and CO2. This enzyme is a key component in alcoholic fermentation and is found in yeast, some bacteria, and various plants.
- Appearance: Solid
- Color: White to off-white
- EC Number: 4.1.1.1
- Unit definition: One unit converts 1 μmol of pyruvic acid to acetaldehyde per minute at pH 6.0, 25°C.
Medchemexpress LLC Pyruvate Carboxylase-IN-5 | 3047101-14-1 | 98.9% | 294.24 | 25 MG
Pyruvate Carboxylase-IN-5 (compound 6m) is a highly selective and permeable inhibitor of pyruvate carboxylase. This mitochondrial enzyme plays a crucial role in catalyzing the carboxylation of pyruvate to oxaloacetate, a process essential for maintaining steady-state levels of Krebs cycle intermediates. These intermediates are vital precursors for the synthesis of biomacromolecules such as amino acids, fatty acids, and glucose.
- High selectivity and permeability
- Inhibits pyruvate carboxylase
- Supports research into metabolism and biosynthesis pathways
Medchemexpress LLC Pyruvate Dehydrogenase E1 beta subunit Antibody (YA114) | Protein A affinity purified | Predicted: 39 kDa; Observed: 34 kDa | 50 UL
Pyruvate Dehydrogenase E1 beta subunit Antibody (YA114) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting the Pyruvate Dehydrogenase E1 beta subunit. This subunit is a key component of the pyruvate dehydrogenase complex, which catalyzes the conversion of pyruvate to acetyl-CoA and CO₂, linking the glycolytic pathway to the tricarboxylic acid cycle.
- Host: Rabbit
- Reactivity: Human, mouse, rat
- Conjugation: Non-conjugated
- Research field: Signal transduction
- Purity: Protein A affinity purified
- Molecular weight: Predicted 39 kDa, observed 34 kDa
- Formulation: Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol with 0.05% Sodium Azide
- Storage: Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
- Applications: WB (1:500-1:2000), IHC-P (1:50-1:200), FC (1:50-1:100), IP (assay dependent)
Medchemexpress LLC Pyruvate decarboxylase (PDC) | 9001-04-1 | ≥1 U/mg solid | 100 U
Pyruvate decarboxylase (PDC) is an enzyme that catalyzes the decarboxylation of pyruvic acid to acetaldehyde. It facilitates the non-oxidative conversion of pyruvate to acetaldehyde and CO2. This enzyme is crucial for alcoholic fermentation and is present in yeast, certain bacteria, and various plants.
- Catalyzes decarboxylation of pyruvic acid to acetaldehyde.
- Facilitates non-oxidative conversion of pyruvate to acetaldehyde and CO2.
- Key enzyme in alcoholic fermentation.
- Found in yeast, bacteria, and plants.
- Subunits are approximately 60 kDa.
Medchemexpress LLC Ethyl pyruvate | 617-35-6 | MFCD00009123 | 250mg
Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate Ethyl pyruvate is an HMGB1 release inhibitor Ethyl pyruvate can induce apoptosis by autophagy Ethyl pyruvate has anti-inflammatory antioxidant and anti-tumor activity Ethyl pyruvate can be used in the study of neurodegenerative diseases such as Alzheimer s and Parkinson s disease[1][2][3][4][5]
Apexbio Technology LLC Ethyl pyruvate 617-35-6 100mg
Ethyl pyruvate (CAS 617-35-6) is an ethyl ester derivative of pyruvic acid known for its anti-inflammatory and antioxidant activities Mechanistically it modulates inflammatory signaling pathways and reduces oxidative stress thereby attenuating cellular and tissue damage in preclinical models Ethyl pyruvate has demonstrated the ability to mitigate inflammatory responses decrease oxidative injury and confer tissue protection in studies of cardiovascular diseases neurodegenerative conditions hepatic injury sepsis and ischemia-reperfusion models It serves as a valuable tool in biomedical research focused on exploring strategies for controlling inflammation and oxidative stress
![Alkali Scientific Pyruvic Acid Sodium Salt, [Sodium Pyruvate], 50 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661396.jpg-250.jpg)
Alkali Scientific Pyruvic Acid Sodium Salt, [Sodium Pyruvate], 50 G
Sodium pyruvate, also known as pyruvic acid sodium salt, is a key buffer component and metabolic intermediate commonly used in cell culture applications. This 50g quantity is typically used for laboratory experiments and medium preparation where a smaller quantity is required for controlled studies. Sodium pyruvate helps maintain pH levels in cell culture media, providing stability and energy support for cells. It plays a crucial role in cellular metabolism by participating in glycolysis and various biochemical processes. This reagent is commonly utilized in laboratory studies involving mammalian cells, stem cells, and metabolic research to promote cell growth, viability, and function under experimental conditions.
![Alkali Scientific Pyruvic Acid Sodium Salt, [Sodium Pyruvate], 500 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661224.jpg-250.jpg)
Alkali Scientific Pyruvic Acid Sodium Salt, [Sodium Pyruvate], 500 G
Sodium pyruvate (pyruvic acid sodium salt) is a widely used reagent in biological research, particularly in cell culture applications. This 500g quantity is ideal for laboratories with high-volume research or production needs, where larger amounts of pyruvate are necessary. Sodium pyruvate acts as a buffer component that stabilizes pH in culture media and also provides an essential energy substrate for cultured cells. It supports cellular metabolism, promotes cell growth, and is used extensively in experiments studying mitochondrial function and glycolysis. Sodium pyruvate is essential for maintaining optimal conditions in cell culture environments, ensuring cell viability and proper cellular function during extended incubation periods.