Hydrobromides
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 100 MG
Eletriptan hydrobromide is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity, exhibiting Ki values of 0.92 nM and 3.14 nM, respectively. It is intended for research use only. In vivo studies have shown that eletriptan hydrobromide dose-dependently reduces carotid blood flow in anesthetized dogs and inhibits dural plasma protein extravasation in anesthetized rats.
- Functions as a 5-HT1B and 5-HT1D receptor agonist.
- Exhibits Ki values of 0.92 nM for 5-HT1B receptor.
- Exhibits Ki values of 3.14 nM for 5-HT1D receptor.
- Dose-dependently reduces carotid blood flow in anesthetized dogs.
- Inhibits dural plasma protein extravasation in anesthetized rats.
- Completely inhibits plasma protein extravasation from the dura mater at 100 μg/kg.
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 1 ML
Eletriptan hydrobromide is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity, primarily used as a laboratory chemical for research purposes. It appears as an off-white to light brown solid with a molecular weight of 463.43.
- 5-HT1B and 5-HT1D receptor agonist
- Demonstrates antimigraine activity
- Ki values of 0.92 nM for 5-HT1B receptor
- Ki values of 3.14 nM for 5-HT1D receptor
- Off-white to light brown solid appearance
- Reduces carotid blood flow in anesthetized dogs (in vivo)
- Inhibits dural plasma protein extravasation in anesthetized rats (in vivo)
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 50 MG
Eletriptan hydrobromide (Eletriptan HBr) is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity, with Ki values of 0.92 nM and 3.14 nM, respectively. It is for research use only and not sold to patients.
- 5-HT1B and 5-HT1D receptor agonist
- Antimigraine activity
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 25 MG
Eletriptan hydrobromide (Eletriptan HBr) is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity. It has Ki values of 0.92 nM for 5-HT1B receptors and 3.14 nM for 5-HT1D receptors.
- Dose-dependently reduces carotid blood flow in anesthetized dogs (1-1000 μg/kg; i.v.)
- Inhibits dural plasma protein extravasation in anesthetized rats (30-300 μg/kg; i.v.)
- Completely inhibits extravasation from the dura mater at 100 μg/kg
- Appears as an off-white to light brown solid
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | MFCD08141806 | 463.43 g/mol | C22H27BrN2O2S | 10 MG
Eletriptan hydrobromide is the hydrobromide salt of eletriptan, a selective 5-HT1B and 5-HT1D receptor agonist supplied as an analytical standard for laboratory and research use.
- Analytical standard suitable for research and assay development.
- Selective 5-HT1B and 5-HT1D agonist for pharmacology studies.
- Reported Ki values: 0.92 nM (5-HT1B) and 3.14 nM (5-HT1D).
- Chemical formula C22H27BrN2O2S; molecular weight ~463.4 g/mol.
- Provided in small masses appropriate for analytical work.