Hydrochlorides
Medchemexpress LLC Piperoxan hydrochloride | 135-87-5 | MFCD00079224 | 99.7% | 269.77 | C14H20ClNO2 | 25 MG
Piperoxan hydrochloride is a research reagent that acts as an α2-adrenoceptor antagonist and is historically classified as a first-generation antihistamine. Supplied as a solid for laboratory use, it has CAS 135-87-5, molecular formula C14H20ClNO2, and molecular weight 269.77 g/mol. Recommended storage is sealed and refrigerated; an SDS is available for handling and safety information.
- Acts as an α2-adrenoceptor antagonist and first-generation antihistamine.
- High purity (99.7%) suitable for research applications.
- Provided as a solid for laboratory handling and formulation.
- Molecular weight 269.77 g/mol and formula C14H20ClNO2.
- SDS available with recommended refrigerated, sealed storage conditions.
![Medchemexpress LLC Cyclopentanecarboxamide, N-[(1S)-4-[(aminoiminomethyl)amino]-1-[2-(2,3,5,6-tetrafluorophenoxy)acetyl]bu | 2097865-47-7 | 97.2% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Cyclopentanecarboxamide, N-[(1S)-4-[(aminoiminomethyl)amino]-1-[2-(2,3,5,6-tetrafluorophenoxy)acetyl]bu | 2097865-47-7 | 97.2% | 25 MG
Kgp-IN-1 hydrochloride is an arginine-specific gingipain (Rgp) inhibitor, identified as compound 13-R from patent WO2017201322A1. This product is intended for research use only.
- Arginine-specific gingipain (Rgp) inhibitor
- Targets cathepsin
- Pathway: metabolic enzyme/protease
- White to off-white solid
- Store at 4°C, sealed, away from moisture
Medchemexpress LLC Erlotinib (hydrochloride) | 183319-69-9 | 99.9% | 50 MG
Erlotinib hydrochloride is a small-molecule epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor supplied as the hydrochloride salt for research use in biochemical and cell-based assays.
- Inhibits EGFR tyrosine kinase with low-nanomolar potency.
- Supplied as a solid hydrochloride salt suitable for analytical and biological studies.
- High purity (99.9% by LCMS) for reliable experimental results.
- Soluble in DMSO for preparation of stock solutions.
- Commonly used in kinase assays and cellular signaling research.
eMolecules 912999-79-2 | 5-Chloroisoindoline hydrochloride | Ambeed | MFCD11223562 | 190.07 | C8H9Cl2N | 98 | Cl.Clc1ccc2CNCc2c1 | 5g | 552537975
5-Chloroisoindoline hydrochloride | Ambeed | 912999-79-2 | MFCD11223562 | 190.070 | C8H9Cl2N | 98.000 | Cl.Clc1ccc2CNCc2c1 | 5g | 552537975
Medchemexpress LLC Nisoxetine | 53179-07-0 | MFCD00865443 | 98.6% | 271.35 | C17H21NO2 | 10 MG
Nisoxetine is a selective norepinephrine transporter (NET) inhibitor intended for research use. It is supplied as a high-purity solid suitable for pharmacology, binding, and analytical studies.
- Selective norepinephrine transporter inhibitor for research use only.
- High purity (≈98.6%) suitable for analytical assays.
- Molecular weight 271.35 and formula C17H21NO2.
- Available in sizes from 5-500 mg to support assay scale-up.
- Supplied with analytical documentation (COA, LCMS, NMR, SDS).
Apexbio Technology LLC VU 0361737 1161205-04-4 5mg
VU 0361737 (CAS 1161205-04-4) is a selective brain-penetrant positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4) It demonstrates high selectivity for mGluR4 over other mGluR subtypes with EC50 values of 240 nM for human and 110 nM for rat mGluR4 and shows minimal to no activity at mGluR1 mGluR2 mGluR3 mGluR6 and mGluR7 while exhibiting weak activity at mGluR5 and mGluR8 VU 0361737 crosses the blood-brain barrier and achieves significant brain exposure (brain plasma ratio of 4 1) with a short half-life (T1/2 20 min) following administration in rats This compound is utilized in studies exploring the modulation of basal ganglia neurotransmission and the pathophysiology of Parkinson s disease
Medchemexpress LLC SB-224289 (hydrochloride) | 180084-26-8 | 99.0% | 557.08 g/mol | C32H33ClN4O3 | 100 MG
SB-224289 hydrochloride is a research-grade selective 5-HT1B receptor antagonist reported to have anxiolytic effects. Supplied as the hydrochloride salt in solid form, it is intended for laboratory research use only and is used in pharmacology and neuroscience studies of 5-HT1B receptor function.
- High purity: 99.0%.
- Cas number: 180084-26-8.
- Molecular formula C32H33ClN4O3; molecular weight 557.08 g/mol.
- Supplied as a 100 MG solid pack.
- Recommended storage under nitrogen at -20°C; in solution -80°C (6 months), -20°C (1 month).
- For research use only; not for human or clinical use.
Medchemexpress LLC Vasicine (hydrochloride) | 7174-27-8 | 98.6% | 224.69 | 5 MG
Vasicine hydrochloride is a quinazoline alkaloid isolated from *Justicia adhatoda*. It activates the PI3K/Akt signaling pathway, demonstrating antioxidant, anti-inflammatory, and antibacterial properties. In vitro studies show it inhibits H+/K+-ATPase, scavenges DPPH free radicals, reduces gastric acid secretion, and has anti-ulcer effects. In vivo, it improves cardiac function, inhibits myocardial cell apoptosis, and alleviates myocardial damage and inflammation.
- Inhibits H+/K+-ATPase and scavenges DPPH free radicals
- Reduces gastric acid secretion; provides anti-ulcer effects
- Improves cardiac function and inhibits myocardial cell apoptosis
- Alleviates myocardial necrosis, edema, and inflammatory cell infiltration
- Reduces LDH and CK-MB levels
- Increases LVSP and myocardial contractility
- Lowers TNF-α and IL-6 levels
- Increases SOD and GPx activities in myocardial tissue
Medchemexpress LLC SKF-96365 hydrochlor 100mg
SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2 entry (SOCE) inhibitor SKF-96365 hydrochloride significantly inhibits hERG hKCNQ1/hKCNE1 hKir2 1 and hKv4 3 current and significantly prolongs the QTc interval in isolated guinea pig hearts SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells1]2]
Medchemexpress LLC 2-iminothiolane hydrochloride | 4781-83-3 | MFCD00039013 | 99.9% | 137.63 g/mol | C4H8ClNS | 5 MG
2-Iminothiolane hydrochloride (Traut's reagent) is a thiolating reagent that converts primary amines into sulfhydryl (-SH) groups via amidine formation, enabling modification of proteins, peptides, and glycans for downstream conjugation and crosslinking. It is provided as a high-purity solid with characterized solubility and storage recommendations for biochemical applications.
- Introduces free sulfhydryl groups into primary amines.
- Enables protein, peptide, and glycan conjugation and crosslinking.
- High purity suitable for biochemical assays.
- Soluble in water and DMSO under specified conditions.
- Stable when stored sealed at recommended temperatures.
Medchemexpress LLC CGP 54626 hydrochloride | 149184-21-4 | 99.8% | 444.76 g/mol | C18H29Cl3NO3P | 1 MG
CGP 54626 hydrochloride is a selective GABAB receptor antagonist for research use. It is supplied as a white to off-white solid with high purity and defined molecular properties, and is commonly used in receptor-binding and functional assays to study GABAB-mediated signaling.
- Selective GABAB receptor antagonist (IC50 ≈ 4 nM).
- High purity (≈99.8%).
- White to off-white solid appearance.
- Recommended storage: protected from light at -20°C; in solution -80°C for long term.
- Suitable for in vitro binding and functional assays.
- For research use only; not for human or veterinary use.
Medchemexpress LLC N-desmethyl venlafaxine hydrochloride | 93413-90-2 | MFCD18711349 | 99.9% | C16H26ClNO2 | 10MG
Wy-45494 hydrochloride (N-desmethyl venlafaxine hydrochloride) is an analytical reference standard of the major active metabolite of venlafaxine supplied as the hydrochloride salt. It is provided with documented characterization and high purity for use in analytical method development, assay validation, and pharmacological research.
- High purity suitable for analytical applications.
- Characterized molecular formula and molecular weight for identification.
- Suitable as a reference standard for chromatography and mass spectrometry.
- Demonstrated activity inhibiting norepinephrine and serotonin reuptake in vitro.
- Provided with a certificate of analysis for traceability.
- Intended for research use only.
Medchemexpress LLC L-NIO dihydrochloride | 159190-44-0 | MFCD09878280 | 97.0% | 246.13 g/mol | C7H17Cl2N3O2 | 1 ML
L-NIO dihydrochloride is a research-grade nitric oxide synthase (NOS) inhibitor provided as a ready-to-use stock solution and as solid quantities for biochemical and in vivo studies. It is used to inhibit iNOS, eNOS, and nNOS in cellular assays and animal models where controlled NOS modulation is required.
- Ready-to-use 10 mM solution in DMSO (1 mL) for consistent dosing.
- High purity suitable for research applications (97.0%).
- Well-characterized compound with CAS registration and molecular weight data.
- Available in both solution and solid formats to suit experimental needs.
- Accompanied by safety and quality documents (SDS and COA) for compliance.
- Suitable for in vitro NOS inhibition assays and in vivo ischemia models.
Medchemexpress LLC Drp1i27 dihydrochloride | C20H28Cl2N6O | 50 MG
DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). It binds to the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. This compound targets Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.
- Directly binds to and inhibits the GTPase activity of human Drp1.
- Increases cellular networks of mitochondria in human and mouse fibroblasts.
- Offers protection against simulated ischemia-reperfusion injury.
- Has a binding affinity of 286 μM in SPR assay and a KD value of 190 μM via MST assay.
- Targets Drp1-mediated mitochondrial fission.
eMolecules 39891-12-8 | 5-Bromo-3-pyridylacetic acid | Combi-Blocks | MFCD00829308 | 216.034 | C7H6BrNO2 | 98.000 | OC(=O)Cc1cncc(Br)c1 | 5g | 482935915
5-Bromo-3-pyridylacetic acid | Combi-Blocks | 39891-12-8 | MFCD00829308 | 216.034 | C7H6BrNO2 | 98.000 | OC(=O)Cc1cncc(Br)c1 | 5g | 482935915