Hydrochlorides
Medchemexpress LLC Bepridil hydrochloride hydrate | 74764-40-2 | 99.9% | 421.02 | 1 ML
Bepridil hydrochloride hydrate is a non-selective, long-acting Ca+ channel antagonist and Na+, K+ channel inhibitor. It possesses antianginal and type I antiarrhythmic effects and functions as a cardiac Na+/Ca2+ exchange (NCX1) inhibitor. It can be used for the research of cardiovascular disorders.
- Blocks Ca2+-dependent action potentials in vascular smooth muscle.
- Inhibits Ca currents and Na currents in cultured ventricular cells.
- Decreases IKs under blockade of IKr.
- Suitable for research into cardiovascular disorders.
Medchemexpress LLC (±)-Bepridil hydrochloride hydrate | 74764-40-2 | 99.9% | 421.02 | 25 MG
Bepridil hydrochloride hydrate is a non-selective, long-acting calcium channel antagonist and sodium, potassium channel inhibitor. It exhibits antianginal and type I antiarrhythmic effects, and also functions as a cardiac Na+/Ca2+ exchange (NCX1) inhibitor. This product is intended for research on cardiovascular disorders.
- Non-selective calcium channel antagonist
- Long-acting
- Sodium channel inhibitor
- Potassium channel inhibitor
- Antianginal effects
- Type I antiarrhythmic effects
- Cardiac Na+/Ca2+ exchange (NCX1) inhibitor
- Blockades of Ca2+-dependent action potentials in vascular smooth muscle
- Blocks Ca currents and Na currents
- Decreases IKs under blockade of IKr
- Exhibits a half-life of averages 33±15 hours after single-dose administration
Medchemexpress LLC 2-Buten-1-amine, 3-fluoro-4-(phenylsulfonyl)-, hydrochloride (1:1), (2Z)- | 2409964-40-3 | C10H13ClFNO2S | 25 MG
PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor, abolishing lysyl oxidase activity. It inhibits LOX with IC50s ranging from 0.2 μM to 3.2 μM across various LOX isoforms, and also reduces deposition and crosslinking of collagen I secreted by human fibroblasts.
- Purity of 99.71%
- Solid, white to off-white appearance
- Molecular weight of 265.73
- Storage conditions: 4°C sealed for solid; -80°C for 6 months or -20°C for 1 month in solvent
- Soluble in DMSO at 100 mg/mL
- Inhibits LOX isoforms including Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4
- Reduces collagen I deposition and crosslinking