DNQX (FG 9041) is a quinoxaline derivative that functions as a selective, potent competitive non-NMDA glutamate receptor antagonist. It exhibits IC50 values of 0.5, 2, and 40 μM for AMPA, kainate, and NMDA receptors, respectively. This compound is known to selectively depolarize thalamic reticular nucleus (TRN) neurons.
- Selective, potent competitive non-NMDA glutamate receptor antagonist
- Exhibits IC50s of 0.5, 2, and 40 μM for AMPA, kainate, and NMDA receptors
- Selectively depolarizes thalamic reticular nucleus (TRN) neurons
- Purity of 99.67%
- Molecular weight of 252.14
- Appears as a white to off-white solid