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EUK-134 is a salen-manganese complex that functions as both a superoxide dismutase and catalase mimetic. It scavenges superoxide and reduces hydrogen peroxide-mediated damage, making it suitable for cell-based assays and in vivo studies of oxidative stress pathways.
Combines superoxide dismutase and catalase activities.
Scavenges superoxide and reduces hydrogen peroxide-mediated damage.
Reported purity of 98.3%.
Molecular weight 416.74 g/mol; molecular formula C18H18ClMnN2O4.
Available in small research quantities, such as 5 mg.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
EUK 134 (CAS 81065-76-1) is a synthetic salen-manganese complex designed to mimic the antioxidant enzymes superoxide dismutase (SOD) and catalase By scavenging reactive oxygen species (ROS) EUK 134 diminishes oxidative stress and attenuates cellular damage In vitro this compound inhibits formation of amyloid fibrils reduces microglial proliferation induced by -amyloid and protects neuronal cells from oxidative injury via inhibition of MAPK signaling In vivo studies indicate that EUK 134 decreases infarct size and neuronal cell death in rodent models of ischemic stroke and kainate-induced neurotoxicity EUK 134 is thus a relevant tool in oxidative stress and neurodegeneration research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
EUK 134 (CAS 81065-76-1) is a synthetic salen-manganese complex designed to mimic the antioxidant enzymes superoxide dismutase (SOD) and catalase By scavenging reactive oxygen species (ROS) EUK 134 diminishes oxidative stress and attenuates cellular damage In vitro this compound inhibits formation of amyloid fibrils reduces microglial proliferation induced by -amyloid and protects neuronal cells from oxidative injury via inhibition of MAPK signaling In vivo studies indicate that EUK 134 decreases infarct size and neuronal cell death in rodent models of ischemic stroke and kainate-induced neurotoxicity EUK 134 is thus a relevant tool in oxidative stress and neurodegeneration research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More