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Organoaluminum compounds possess direct bonds between carbon and aluminum atoms. Predominantly electrophilic, these compounds typically act as Lewis acids in reactions and play a large role in the field of organometallic chemistry.
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Acetoacetic acid (lithium) is the lithium salt of acetoacetic acid supplied as a research reagent for biochemical and cell-based studies. It functions as an oxidative stress inducer and is provided as a small-quantity solid suitable for preparing aqueous or DMSO solutions for in vitro experiments.
Oxidative stress inducer for cell and biochemical assays.
High nominal purity (98.0%).
Supplied as a 5 mg vial for small-scale research use.
Soluble in water and DMSO for flexible formulation.
Molecular weight 108.02 g/mol; formula C4H6LiO3.
CAS number 3483-11-2 for unambiguous identification.
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Acetoacetic acid is an oxidative stress inducer. It affects the antioxidant enzyme system and lipoprotein metabolism by decreasing mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), and increasing malondialdehyde (MDA) content. It also inhibits very low-density lipoprotein (VLDL) assembly, leading to triglyceride (TG) accumulation in hepatocytes, making it useful for studying metabolic diseases.
Oxidative stress inducer
Impacts antioxidant enzyme system
Affects lipoprotein metabolism
Decreases SOD, CAT, and GSH-Px activity and mRNA expression
Increases malondialdehyde (MDA) content
Inhibits VLDL assembly
Leads to triglyceride (TG) accumulation in hepatocytes
Useful for studying metabolic diseases
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Also available in 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Purity ≥98%
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Acetoacetic acid sodium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. It can be used to study metabolic diseases. The sodium salt form of the compound is prone to thermal instability.
Induces oxidative stress by decreasing mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px)
Increases MDA content
Inhibits very low density lipoprotein (VLDL) assembly
Downregulates apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR)
Leads to triglyceride (TG) accumulation in hepatocytes
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More