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Organocopper compounds have bonds between carbon and copper atoms and commonly have Cu(I) oxidation states. As organic chemistry reagents, they are used during organic synthesis as mild, selective nucleophiles for substitution and conjugate addition reactions.
Cu is present in 1 (cuprous) valence state in CuCl. CuCl is a semiconductor having a wide band gap. It is a promising candidate for use in silicon-based optoelectronics since its lattice resembles with silicon. It participates in various reactions with Grignard reagents.
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Elastin methacrylated is a methacrylated elastin polymer designed as a photocrosslinkable hydrogel precursor for 3D bioprinting, cell culture, and tissue engineering. It promotes immune cell recruitment and supports angiogenesis and collagen deposition when formed into hydrogels and cured under blue light.
Photocrosslinkable hydrogel precursor suitable for 3D bioprinting and cell culture.
Promotes recruitment of innate immune cells and supports angiogenesis and tissue regeneration.
Forms fibrous hydrogels with tunable mechanical properties at higher concentrations.
Compatible with blue-light photoinitiators and curing at 365-405 nm.
Can be sterilized by 0.22 μm filtration; avoid repeated freeze-thaw cycles.
Stable as a powder at -20°C; store solutions cold and minimize room temperature exposure.
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DOTA-EB-TATE is a peptide drug conjugate (PDC) consisting of an SST peptide derivative, DOTA-octreotate, conjugated to an Evans blue analog (EB). This compound is designed to improve the pharmacokinetics of SSTR2 analogs and reduce PRRT toxicity.
Composed of an SST peptide derivative, DOTA-octreotate conjugated to an Evans blue analog
Improves the pharmacokinetics of SSTR2 analogs
Reduces PRRT toxicity
Can be used for the synthesis and research of Radionuclide-Drug Conjugates (RDCs)
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Mangafodipir trisodium (MnDPDP) is a hepatocellular-specific contrast agent and an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropathy) and other conditions caused by cellular oxidative stress. It shows no negative interference with the tumoricidal activity of chemotherapy.
Hepatocellular-specific contrast agent.
Efficacious inhibitor of CIPN and other conditions caused by cellular oxidative stress.
Shows no negative interference with the tumoricidal activity of chemotherapy.
Inhibits the effect of HGrC cell viability caused by H2O2 (in vitro).
Attenuates apoptosis caused by cisplatin in HGrC cells (in vitro).
Shows protective effects against ovarian damage caused by cisplatin and paclitaxel in mice (in vivo).
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