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Organo-Post-Transition Metal Compounds

Organo-post-transition metal compounds possess direct bonds between carbon atoms and post-transition metal atoms. Organo-post-transition metal compounds are available in a range of chemical compositions, quantities, and purities.

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1

Medchemexpress LLC PI3K/Akt/CREB activator 1 | 2708177-73-3 | C19H15F4NO3 | 25 MG
SDP

PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. It promotes neuronal proliferation, induces differentiation of Neuro-2a cells into a neuron-like morphology, and accelerates the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. This product can be used in research of vascular dementia (VaD).

  • Potent, orally active PI3K/Akt/CREB activator.
  • Promotes neuronal proliferation.
  • Induces differentiation of Neuro-2a cells into a neuron-like morphology.
  • Accelerates axon-dendrite polarization of primary hippocampal neurons.
  • Enhances neuronal differentiation and axon-dendrite polarization in cultured hippocampal neurons.
  • Improves cerebral blood flow recovery and mitigates learning and memory impairment in chronic cerebral hypoperfusion animal models.

ENCOMPASS_PREFERRED
2

Medchemexpress LLC PI3K/Akt/CREB activator 1 (compound AE-18) | 2708177-73-3 | C19H15F4NO3 | 100 MG
SDP

PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active activator that promotes neuronal proliferation, induces differentiation, and accelerates axon-dendrite polarization. It functions by upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway and is suitable for research into vascular dementia (VaD).

  • Promotes neuronal proliferation
  • Induces differentiation of Neuro-2a cells into a neuron-like morphology
  • Accelerates axon-dendrite polarization of primary hippocampal neurons
  • Upregulates brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway
  • Mitigates impairment of learning and memory in chronic cerebral hypoperfusion models
  • Alleviates pathological injury in the hippocampus
  • Improves cerebral blood flow recovery

ENCOMPASS_PREFERRED
3

Medchemexpress LLC PI3K/Akt/CREB activator 1 (compound AE-18) | 2708177-73-3 | C19H15F4NO3 | 50 MG
SDP

PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active activator that promotes neuronal proliferation, induces differentiation of Neuro-2a cells, and accelerates axon-dendrite polarization of primary hippocampal neurons. It achieves this by upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway and is used in vascular dementia (VaD) research.

  • Promotes neuronal proliferation and differentiation
  • Accelerates axon-dendrite polarization of primary hippocampal neurons
  • Upregulates brain-derived neurotrophic factor (BDNF)
  • Improves cerebral blood flow recovery in models of chronic cerebral hypoperfusion (CCH)
  • Mitigates impairment of learning and memory in CCH models
  • Alleviates CCH-induced pathological injury in the hippocampus

ENCOMPASS_PREFERRED