Heptane
Medchemexpress LLC N'-Hexadecylthiophene-2-carbohydrazide | 2374313-54-7 | 99.43% | 10 MG
SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM. It inhibits the demyristoylation of serine hydroxymethyltransferase 2, a substrate of HDAC 11, but does not inhibit other HDACs. This product is for research use only.
- IC50 value of 0.83 μM for HDAC11
- Inhibits demyristoylation of serine hydroxymethyltransferase 2
- Does not inhibit other HDACs
- Increases fatty acylation level of SHMT2 in MCF7 cells
- Demonstrates synergistic cytotoxicity with Oxaliplatin in K562 cells
- White to off-white solid appearance
- Purity of 99.43%
Medchemexpress LLC 1h-isoindole-1,3(2h)-dione, 2-[2-(3,4-dihydro-2,2,4-trimethyl-1(2h)-quinolinyl)-2-oxoethyl]- | 332382-54-4 | 99.4% | 362.42 | 10 MG
ML-SA1 is a selective TRPML agonist that inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. It induces autophagy and can be used for research as a broad-spectrum antiviral.
- Selective TRPML agonist
- Inhibits dengue virus 2 (DENV2) and zika virus (ZIKV)
- Promotes lysosomal acidification and protease activity
- Induces autophagy
- Broad-spectrum antiviral research
Medchemexpress LLC MID-1 100mg | 312608-54-1 | 293.30 g·mol-1 | C12H11N3O4S | 100 MG
MID-1 (Benzamide, 4-ethoxy-N-(5-nitro-2-thiazolyl); CAS 312608-54-1) is a small-molecule disruptor of the MG53-IRS-1 interaction that increases IRS-1 protein levels and enhances insulin signaling in vitro. It is supplied as a solid and as a 10 mM solution in DMSO for research use.
- Disrupts MG53-IRS-1 protein-protein interaction in vitro.
- Increases IRS-1 protein level and insulin signaling.
- Available as solid and as 10 mM DMSO solution.
- High purity (≈99.4%).
Medchemexpress LLC N-(2-(2-acrylamidophenyl)-4-(pyridin-4-yl)thiazol-5-yl)-2-(difluoromethyl)benzamide | 2227368-54-7 | MFCD34593626 | 99.0% | 452.46 g/mol | C25H20N6O3 | 25 MG
Potent and selective IRAK1 inhibitor for research use. The compound inhibits IRAK1 with an apparent IC50 of 9 nM and shows no inhibition of IRAK4 at concentrations up to 10 μM. Supplied as a solid or as a DMSO solution, it provides defined solubility and storage properties.
- Potent, selective IRAK1 inhibition with an apparent IC50 of 9 nM.
- High purity (99.03%) for reliable experimental results.
- Available as solid and as 10 mM solutions in DMSO for flexible dosing.
- Molecular weight 452.46 g/mol; molecular formula C25H20N6O3.
- High solubility in DMSO (125 mg/mL) and in vivo formulation solubility ≥1.98 mg/mL under protocol conditions.
- Stable storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).