Tetrahydrofuran
Medchemexpress LLC AST5902 trimesylate | 2929417-90-1 | 98.75% | 842.88 | 100 MG
AST5902 trimesylate is the principal metabolite of Alflutinib in vitro and in vivo. It exhibits antineoplastic activity, and Alflutinib is known as an EGFR inhibitor.
- Principal metabolite of Alflutinib
- Exhibits antineoplastic activity
- Targets EGFR
Medchemexpress LLC SR8278 | 1254944-66-5 | 99.94% | C18H19NO3S2 | 100 MG
SR8278 is a REV-ERBα antagonist that inhibits its transcriptional repression activity with an EC50 of 0.47 μM.
- Used to regulate metabolism in organisms
- Studies biological rhythm
- Researches Duchenne muscular dystrophy
- Researches Alzheimer's disease
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran | 109-99-9 | MFCD00005356 | 6x1l
Tetrahydrofuran | Purity: 99% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 6x1l
Sigma Aldrich Fine Chemicals Biosciences 2 Methyltetrahydrofuran Bi
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with Safer Solvents and Auxiliaries and Use of Renewable feedstocks. Click here for more information.2-Methyltetrahydrofuran (2-MTHf) a 2-methyl substituted tetrahdrofuran is a biomass derived solvent. It is a potential greener solvent alternative for organic synthesis. It shows resistance to reduction by lithium making it a promising candidate as electrolytes in lithium batteries. Its polarity and Lewis base strength is intermediate between tetrahydrofuran (THf) and diethyl ether. The ring opening reaction of 2-MTHf has been studied using acid chloride and iodide to form secondary chlorides and primary iodides respectively. On long term storage tetrahydrofuran forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals re
Medchemexpress LLC Dalpiciclib 50mg | 1637781-04-4 | 50 MG
Dalpiciclib is an orally active, selective inhibitor of cyclin-dependent kinases CDK4 and CDK6 intended for preclinical research use. It is supplied as a powder and is characterized by CAS 1637781-04-4, molecular formula C25H30N6O2, and molecular weight 446.54 g/mol. For research use only; not for human or clinical use.
- Selective CDK4/6 inhibition with low-nanomolar potency
- High chemical purity suitable for analytical and biological studies
- Supplied as a powder for flexible formulation and dosing
- Stable under recommended storage conditions for long-term use
- Characterized by validated analytical data and CAS identification
![Medchemexpress LLC 2-[[4-(diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid | 140405-36-3 | 99.7% | 312.37 | C17H20N4O2 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247220.png-250.jpg)
Medchemexpress LLC 2-[[4-(diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid | 140405-36-3 | 99.7% | 312.37 | C17H20N4O2 | 25 MG
RSVA405 is a potent, orally active activator of AMP-activated protein kinase (AMPK) used in preclinical research. It facilitates CaMKKβ-dependent AMPK activation, inhibits mTOR, promotes autophagy and lysosomal degradation of Aβ, and exhibits anti-inflammatory effects via STAT3 inhibition. Activity is observed in vitro (EC50 ≈ 1 μM) and in vivo in metabolic and renal models.
- Potent AMPK activator with an EC50 of approximately 1 μM.
- Promotes autophagy and lysosomal degradation of Aβ.
- Inhibits mTOR and modulates adipocyte differentiation.
- Exhibits anti-inflammatory effects through STAT3 inhibition.
- Demonstrated in vitro and in vivo activity in metabolic and renal models.
- Supplied as a light yellow to yellow solid with high purity.
Medchemexpress LLC Ceftaroline | 189345-04-8 | 96.9% ; 98.5% | 604.7 g/mol | C22H20N8O5S4 | 50 MG
Ceftaroline is an N-phosphono-type cephalosporin antibiotic and the active form of the prodrug ceftaroline fosamil. It exhibits activity against both Gram-positive and Gram-negative bacteria and is supplied as a research reagent for antibacterial studies.
- Active metabolite of the prodrug ceftaroline fosamil.
- Broad-spectrum activity against Gram-positive and Gram-negative bacteria.
- Useful as a research reagent for antibacterial and microbiology studies.
- Supplied in multiple package sizes for experimental needs.
- High reported purity suitable for analytical applications.
Medchemexpress LLC (R)-Tetrahydrofuran-2-carboxylic acid | 87392-05-0 | 116.12 | 5 G
(R)-Tetrahydrofuran-2-carboxylic acid is a chiral building block for Faropenem, a clinically effective non-natural β-lactam antibiotic. This product is intended for research use only.
- High purity of 99.93%
- Molecular weight of 116.12
- Chemical formula C5H8O3
- Appears as a colorless to light yellow liquid with a density of 1.209 g/cm³
- Stable for 3 years when stored at room temperature
- Can be stored in solvent at -80°C for 2 years or -20°C for 1 year
Medchemexpress LLC Nerigliatin | 1245603-92-2 | 99.9% | 432.43 g/mol | C22H20N6O4 | 10 MG
Nerigliatin is a small-molecule glucokinase activator used for laboratory research into glucose-lowering mechanisms. It has demonstrated glucose-lowering efficacy in preclinical studies but has been associated with peripheral nerve degeneration in reported results. Intended for research use only and not for human or clinical applications.
- Glucokinase activator for glucose-lowering research.
- High purity (99.94%).
- Molecular weight 432.43 g/mol.
- Soluble in DMSO at 100 mg/mL with ultrasonic assistance.
- Available in multiple small-scale solid quantities suitable for lab studies.
- Not intended for clinical or human use; handle with appropriate safety precautions.
Medchemexpress LLC Pd-1/pd-l1-in-23 | 2597056-04-5 | 100.0% | 703.41 g/mol | C32H30BrCl2N3O6 | 5 MG
PD-1/PD-L1-IN-23 is a small-molecule inhibitor of the PD-1/PD-L1 immune checkpoint provided as a research reagent. Described as an orally active ester prodrug of L7, it is supplied as a solid suitable for biochemical assays and preclinical studies. CAS 2597056-04-5; molecular formula C32H30BrCl2N3O6; molecular weight 703.41 g/mol.
- Potent small-molecule inhibitor of PD-1/PD-L1 interaction
- Orally active prodrug with demonstrated preclinical activity
- Designed to convert to an active metabolite in vivo
- Solid, white to off-white form with high purity (99.98%)
- Soluble in DMSO; available as solution and powder formats
- Available in multiple research-scale package sizes including 5 mg
![Medchemexpress LLC N,N′-1,3-phenylenebis-[2,3-dihydroxy-benzamide] | 368449-04-1 | 98.6% | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232924.png-250.jpg)
Medchemexpress LLC N,N′-1,3-phenylenebis-[2,3-dihydroxy-benzamide] | 368449-04-1 | 98.6% | 10 MG
MST-312 (telomerase inhibitor IX) is a small-molecule telomerase inhibitor used in research to study telomerase-dependent pathways and anticancer activity. It is a bis-catechol derivative of epigallocatechin gallate and is used in cell-based assays to reduce proliferation and induce apoptosis in sensitive lines.
- Inhibits telomerase activity in cell-based assays.
- Derivative of epigallocatechin gallate (EGCG).
- High purity (≈98.6%).
- Molecular weight 380.35 g/mol.
- Available as solid and as 10 mM solution in DMSO.
- Recommended storage: powder at -20°C; in solvent at -80°C.
![eMolecules 87151-60-8 | 1-oxaspiro[4.5]decan-8-one | MFCD09759212 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502136139.JPG-250.jpg)
eMolecules 87151-60-8 | 1-oxaspiro[4.5]decan-8-one | MFCD09759212 | 1g
Pharmablock | 1-oxaspiro[4.5]decan-8-one | 1g | 551144307 | PBP11073 | 87151-60-8 | MFCD09759212 | 154.209 | C9H14O2
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Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran anhydrous
Tetrahydrofuran (THf) is a saturated cyclic ether with a potential use as a biofuel. Its combustion studies have been investigated. Reports suggest that it is a better promoter than 1 3 dioxolane for CO2-hydrate formation.
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofurfuryl alcohol
Tetrahydrofurfuryl alcohol is one of the aroma constituents of coffee.
Medchemexpress LLC Tienilic acid | 40180-04-9 | MFCD00867339 | 99.7% | 331.18 | C13H8Cl2O4S | 10 MG
Tienilic acid is a research-grade analytical standard used as a reference compound in biochemical and pharmacological studies. It is supplied as a solid powder with high analytical purity and should be handled and stored according to supplier safety data sheet recommendations.
- High purity: 99.7%.
- Molecular weight 331.18.
- Chemical formula C13H8Cl2O4S.
- CAS number 40180-04-9.
- Solid form; store at 4°C protected from light.
- In-solution storage: -80°C up to 6 months, -20°C up to 1 month.